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P04.81 ICD-10-CM Code: Newborn affected by maternal use of cannabis

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FY 2026 Apr update / Certain conditions originating in the perinatal period (P00-P96) / Newborn affected by maternal factors and by complications of pregnancy, labor, and delivery (P00-P04)

P04.81

Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidance

Newborn affected by maternal use of cannabis

A newborn whose mother used cannabis (marijuana) during pregnancy, which may affect the baby's development and behavior.

Buddy the Bee presenting code insight

Buddy Insight

Maternal cannabis use during pregnancy can affect fetal brain development and may cause subtle neurobehavioral effects in newborns including altered sleep patterns and behavioral regulation.

CMS-HCC V28

HCC 137

RAF 0.424

CMS-HCC V24

N/A

Not mapped

ACA/HHS

HCC 82

Varies by metal level

ESRD/PACE

N/A

Not mapped

RXHCC

N/A

Not mapped

Code Book Path

Official
P04Newborn affected by noxious substances transmitted via placenta or breast milk
P04.8Newborn affected by other maternal noxious substances
P04.81Newborn affected by maternal use of cannabis

Inclusion Terms

Official

ICD-10-CM does not list inclusion terms for P04.81 in this effective period.

Excludes 2

Official

ICD-10-CM does not list Excludes 2 notes for P04.81 in this effective period.

Related Child Codes

Official
P04.89Newborn affected by other maternal noxious substances

Includes

Official

ICD-10-CM does not list Includes notes for P04.81 in this effective period.

Excludes 1

Official

ICD-10-CM does not list Excludes 1 notes for P04.81 in this effective period.

Code First

Official

ICD-10-CM does not list Code First sequencing instructions for P04.81 in this effective period.

Use Additional

Official

ICD-10-CM does not list Use Additional Code instructions for P04.81 in this effective period.

Code Also

Official

ICD-10-CM does not list Code Also instructions for P04.81 in this effective period.

Buddy Documentation Tip

HCC Buddy guidance
Documentation of maternal cannabis use during pregnancy
Frequency and method of cannabis use
Timing of use relative to pregnancy stages
Clinical observations of newborn behavior

MEAT Support

HCC Buddy guidance
Documentation of maternal cannabis use during pregnancy
Frequency and method of cannabis use
Timing of use relative to pregnancy stages
Clinical observations of newborn behavior

Audit Caution

HCC Buddy guidance
Confusing cannabis with other psychoactive substances
Using general drug addiction codes when cannabis specific
Missing documentation of cannabis-specific effects
Incorrectly coding behavioral observations as separate conditions

Common Mistakes

HCC Buddy guidance
P04.42 — Newborn affected by maternal use of hallucinogens (hallucinogens vs cannabis)
P04.40 — Newborn affected by maternal use of unspecified drugs of addiction
P96.89 — Other specified conditions originating in the perinatal period
P04.89 — Newborn affected by other maternal noxious substances

Current with CMS: FY2026 ICD-10-CM Apr 1 update (effective Apr 1 – Sep 30, 2026) · CMS-HCC V28, 100% phased in for payment year 2026. FY2027 code set already staged for October 1, 2026. How HCC Buddy stays current →

Is P04.81 an HCC code?

Yes. P04.81 (Newborn affected by maternal use of cannabis) maps to Drug Use Disorder, Moderate/Severe, or Drug Use with Non-Psychotic Complications under the CMS-HCC V28 risk adjustment model, with a community non-dual aged RAF of 0.424. It is billable for payment year 2026.

Coder answer: P04.81 is billable and maps to V28 HCC 137, Drug Use Disorder, Moderate/Severe, or Drug Use with Non-Psychotic Complications. Open it in the Code Book for the tabular path, RAF, and MEAT checklist.

Code
P04.81
Description
Newborn affected by maternal use of cannabis
HCC (V28)
HCC 137 — Drug Use Disorder, Moderate/Severe, or Drug Use with Non-Psychotic Complications
RAF
0.424
Billable
Yes
Payment year
2026

HCC Category Mapping

V28HCC 137, Drug Use Disorder, Moderate/Severe, or Drug Use with Non-Psychotic Complications
0.424

Each model's RAF is its CMS base weight for that model's standard population, so weights are not directly comparable across models: CMS-HCC V28 and V24 use Community, Non-Dual, Aged; ESRD uses the dialysis continuing-enrollee model; RxHCC is the Part D continuing-enrollee, non-low-income, aged weight (a larger scale than CMS-HCC). ACA/HHS has no single weight — it varies by metal level. Actual per-patient RAF contribution depends on member segment, interactions, and the model year used by the payer. V28 is the CMS-HCC model phased in over payment years 2024–2026; V24 remains in use during the transition and for historical data.

Work P04.81 in the Code Book — tabular path, V28 RAF, and MEAT checklist →

MEAT Criteria for P04.81

For P04.81 to count as a valid HCC diagnosis in a given encounter, the provider's documentation must show MEAT: Monitor, Evaluate, Assess, or Treat. A diagnosis from a prior year does not carry forward automatically, it has to be re-documented and supported each calendar year.

  • MMonitor: signs, symptoms, disease progression, or lab trending documented in the note
  • EEvaluate: test results, medication response, or physical findings reviewed by the provider
  • AAssess: explicit mention in the assessment or plan with acknowledgment of status
  • TTreat: medication, referral, procedure, therapy, or counseling tied to the diagnosis

Only one of M/E/A/T is required to support the code, but the documentation must be specific enough to show that the provider actually addressed P04.81 during that encounter, not just copy-forwarded from a problem list.

Coder workflow notes

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What This Code Means

P04.81 is the ICD-10-CM diagnosis code for newborn affected by maternal use of cannabis. A newborn whose mother used cannabis (marijuana) during pregnancy, which may affect the baby's development and behavior. P04.81 sits in the ICD-10-CM chapter for certain conditions originating in the perinatal period (p00-p96), within the section covering newborn affected by maternal factors and by complications of pregnancy, labor, and delivery (p00-p04).

Under the CMS-HCC V28 risk adjustment model, P04.81 maps to Drug Use Disorder, Moderate/Severe, or Drug Use with Non-Psychotic Complications (HCC 137) with a community, non-dual, aged base RAF weight of 0.424. P04.81 was not retained as a payment HCC under the older V24 model, so V28 introduced or recategorized it during the 2024–2026 phase-in. V28 is the CMS-HCC risk adjustment model that reached 100% phase-in for payment year 2026, replacing V24 which was used during the PY2024–PY2025 transition.

Specify the trimester of exposure if documented, as timing affects fetal impact. Because P04.81 maps to a payment HCC, the provider's documentation must satisfy MEAT criteria (Monitor, Evaluate, Assess, or Treat) for the encounter to count toward the patient's Medicare Advantage risk adjustment score. When documentation is ambiguous, coders should issue a provider query rather than assume the highest-specificity variant.

HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for P04.81 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Coding Tips

  • Specify the trimester of exposure if documented, as timing affects fetal impact
  • Document any neonatal manifestations such as poor feeding, irritability, or developmental delays with additional codes

Clinical Significance

Maternal cannabis use during pregnancy can affect fetal brain development and may cause subtle neurobehavioral effects in newborns including altered sleep patterns and behavioral regulation. These infants require monitoring for potential cognitive and behavioral development issues.

Documentation Requirements

  • Documentation of maternal cannabis use during pregnancy
  • Frequency and method of cannabis use
  • Timing of use relative to pregnancy stages
  • Clinical observations of newborn behavior
  • Sleep patterns and behavioral regulation assessment
  • Neurological examination findings
  • Developmental monitoring plans established

Commonly Confused Codes

  • P04.42: Newborn affected by maternal use of hallucinogens (hallucinogens vs cannabis)
  • P04.40: Newborn affected by maternal use of unspecified drugs of addiction
  • P96.89: Other specified conditions originating in the perinatal period
  • P04.89: Newborn affected by other maternal noxious substances

Child Codes

Code Hierarchy

P04.81 code history

Code setChange
FY2019 (effective Oct 1, 2018)Added to the code set

Source: official CMS ICD-10-CM order and addenda files, FY2016 through FY2027.

Because P04.81 maps to a payment HCC, the documentation must also satisfy MEAT criteria (Monitor, Evaluate, Assess, or Treat) for the encounter to count toward the patient's risk adjustment score.

P04.81 maps to CMS-HCC V28 category 137, Drug Use Disorder, Moderate/Severe, or Drug Use with Non-Psychotic Complications. See the ICD-10 to HCC mapping hub for how the V28 crosswalk works. Because P04.81 carries a payment HCC, you can see what it adds to a RAF score and check the documentation the chart needs before it is submitted.

Work P04.81 in HCC Buddy

Open P04.81 in the Code Book for the full Index-to-Tabular path, MEAT checklist, and V28 HCC mapping, or in the Encoder to code from a keyword search. Pro includes 7 days to try everything, no card required.