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O21 ICD-10-CM Code: Excessive vomiting in pregnancy

ICD-10-CM Code View

HCC Buddy Code Card

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FY 2026 Apr update / Pregnancy, childbirth and the puerperium (O00-O9A) / Other maternal disorders predominantly related to pregnancy (O20-O29)

O21

Header CodeICD-10-CMOfficial ICD-10-CMCodebook guidance

Excessive vomiting in pregnancy

Excessive vomiting in pregnancy

CMS-HCC V28

N/A

Not mapped

CMS-HCC V24

N/A

Not mapped

ACA/HHS

N/A

Not mapped

ESRD/PACE

N/A

Not mapped

RXHCC

N/A

Not mapped

Code Book Path

Official
O2Other maternal disorders predominantly related to pregnancy (O20-O29)
O21Excessive vomiting in pregnancy

Inclusion Terms

Official

ICD-10-CM does not list inclusion terms for O21 in this effective period.

Excludes 2

Official

ICD-10-CM does not list Excludes 2 notes for O21 in this effective period.

Related Child Codes

Official
O21.0Mild hyperemesis gravidarum
O21.1Hyperemesis gravidarum with metabolic disturbance
O21.2Late vomiting of pregnancy
O21.8Other vomiting complicating pregnancy
O21.9Vomiting of pregnancy, unspecified

Includes

Official

ICD-10-CM does not list Includes notes for O21 in this effective period.

Excludes 1

Official

ICD-10-CM does not list Excludes 1 notes for O21 in this effective period.

Code First

Official

ICD-10-CM does not list Code First sequencing instructions for O21 in this effective period.

Use Additional

Official

ICD-10-CM does not list Use Additional Code instructions for O21 in this effective period.

Code Also

Official

ICD-10-CM does not list Code Also instructions for O21 in this effective period.

Last updated: FY2026 ICD-10-CM Apr update, Apr 1, 2026 through Sep 30, 2026. CMS-HCC V28 is 100% phased in for payment year 2026.

Coder workflow notes

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What This Code Means

O21 is the ICD-10-CM diagnosis code for excessive vomiting in pregnancy. O21 sits in the ICD-10-CM chapter for pregnancy, childbirth and the puerperium (o00-o9a), within the section covering other maternal disorders predominantly related to pregnancy (o20-o29).

Header codes like O21 cannot be reported on claims directly, they organize child codes that share clinical context but the actual diagnosis must be coded to the highest level of specificity supported by the documentation. Coders should look at O21's child codes and select the one that matches the patient's documented presentation, since payers reject header codes submitted as the primary diagnosis. For risk adjustment workflows, header codes never contribute to a Medicare Advantage member's RAF score on their own; only billable child codes that happen to map to a payment HCC affect risk-adjusted plan payments.

HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for O21 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Child Codes

Code Hierarchy

O21Excessive vomiting in pregnancy
O21Excessive vomiting in pregnancy

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