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G21.19 ICD-10-CM Code: Other drug induced secondary parkinsonism

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FY 2026 Apr update / Diseases of the nervous system (G00-G99) / Extrapyramidal and movement disorders (G20-G26)

G21.19

Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidance

Other drug induced secondary parkinsonism

Parkinson-like symptoms caused by medications other than neuroleptics, such as certain antiemetics, antidepressants, or other drugs.

Buddy the Bee presenting code insight

Buddy Insight

Other drug induced secondary parkinsonism captures parkinsonian symptoms caused by medications other than neuroleptics, such as antiemetics (metoclopramide), calcium channel blockers, valproic acid, or lithium.

CMS-HCC V28

0

0

RAF 0

CMS-HCC V24

HCC 78

RAF 0.606

ACA/HHS

0

0

RAF 0

ESRD/PACE

HCC 78

RAF 0.0

RXHCC

HCC 161

RAF 0.0

Code Trumping

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Code Book Path

Official
G21Secondary parkinsonism
G21.1Other drug-induced secondary parkinsonism
G21.19Other drug induced secondary parkinsonism

Inclusion Terms

Official
  • Other medication-induced parkinsonism

Excludes 2

Official

ICD-10-CM does not list Excludes 2 notes for G21.19 in this effective period.

Related Child Codes

Official
G21.11Neuroleptic induced parkinsonism

Includes

Official

ICD-10-CM does not list Includes notes for G21.19 in this effective period.

Excludes 1

Official

ICD-10-CM does not list Excludes 1 notes for G21.19 in this effective period.

Code First

Official

ICD-10-CM does not list Code First sequencing instructions for G21.19 in this effective period.

Use Additional

Official
  • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)

Code Also

Official

ICD-10-CM does not list Code Also instructions for G21.19 in this effective period.

Buddy Documentation Tip

HCC Buddy guidance
Specific non-neuroleptic medication identified as the cause
Temporal relationship between drug exposure and symptom development
Parkinsonian features documented on examination
Provider statement attributing symptoms to the medication

MEAT Support

HCC Buddy guidance
Specific non-neuroleptic medication identified as the cause
Temporal relationship between drug exposure and symptom development
Parkinsonian features documented on examination
Provider statement attributing symptoms to the medication

Audit Caution

HCC Buddy guidance
Using G21.11 (neuroleptic-induced) when the causative drug is not an antipsychotic
Coding idiopathic Parkinson's disease when symptom onset correlates with medication start
Not coding the specific drug adverse effect T-code as a secondary diagnosis
Failing to recognize that metoclopramide is the most common non-neuroleptic cause of drug-induced parkinsonism

Common Mistakes

HCC Buddy guidance
G21.11 — Neuroleptic induced parkinsonism: specifically for antipsychotic medications
G20.A1-G20.C — Parkinson's disease: idiopathic, not drug-induced
G25.1 — Drug-induced tremor: tremor alone without full parkinsonian syndrome
G21.2 — Secondary parkinsonism due to other external agents: for non-drug causes like toxins

Last updated: FY2026 ICD-10-CM Apr update, Apr 1, 2026 through Sep 30, 2026. CMS-HCC V28 is 100% phased in for payment year 2026.

Is G21.19 an HCC code?

Yes. G21.19 maps to Parkinson's and Huntington's Diseases under the V24 model but is not retained in V28.

HCC Category Mapping

V24HCC 78, Parkinson's and Huntington's Diseases
0.606
ESRDHCC 78, Parkinson's and Huntington's Diseases
0.000
RxHCCHCC 161, Parkinson's Disease and Other Movement Disorders
0.000

RAF weights shown are the community, non-dual, aged base weights from the CMS risk adjustment model file. Actual per-patient RAF contribution depends on member segment, interactions, and the model year used by the payer. V28 is the CMS-HCC model phased in over payment years 2024–2026; V24 remains in use during the transition and for historical data.

Work G21.19 in the Code Book — tabular path, V28 RAF, and MEAT checklist →

MEAT Criteria for G21.19

For G21.19to count as a valid HCC diagnosis in a given encounter, the provider's documentation must show MEAT: Monitor, Evaluate, Assess, or Treat. A diagnosis from a prior year does not carry forward automatically, it has to be re-documented and supported each calendar year.

  • MMonitor: signs, symptoms, disease progression, or lab trending documented in the note
  • EEvaluate: test results, medication response, or physical findings reviewed by the provider
  • AAssess: explicit mention in the assessment or plan with acknowledgment of status
  • TTreat: medication, referral, procedure, therapy, or counseling tied to the diagnosis

Only one of M/E/A/T is required to support the code, but the documentation must be specific enough to show that the provider actually addressed G21.19 during that encounter, not just copy-forwarded from a problem list.

Coder workflow notes

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What This Code Means

G21.19 is the ICD-10-CM diagnosis code for other drug induced secondary parkinsonism. Parkinson-like symptoms caused by medications other than neuroleptics, such as certain antiemetics, antidepressants, or other drugs. G21.19 sits in the ICD-10-CM chapter for diseases of the nervous system (g00-g99), within the section covering extrapyramidal and movement disorders (g20-g26).

Under the older CMS-HCC V24 model, G21.19 maps to Parkinson's and Huntington's Diseases (HCC 78) with a community, non-dual, aged base RAF weight of 0.606. V28 is the CMS-HCC risk adjustment model that reached 100% phase-in for payment year 2026, replacing V24 which was used during the PY2024–PY2025 transition.

Clearly identify the specific medication causing the secondary parkinsonism in the documentation. Because G21.19 maps to a payment HCC, the provider's documentation must satisfy MEAT criteria (Monitor, Evaluate, Assess, or Treat) for the encounter to count toward the patient's Medicare Advantage risk adjustment score. When documentation is ambiguous, coders should issue a provider query rather than assume the highest-specificity variant.

HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for G21.19 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Coding Tips

  • Clearly identify the specific medication causing the secondary parkinsonism in the documentation
  • Code the adverse effect of the causative drug using the appropriate T-code from the poisoning section

Clinical Significance

Other drug induced secondary parkinsonism captures parkinsonian symptoms caused by medications other than neuroleptics, such as antiemetics (metoclopramide), calcium channel blockers, valproic acid, or lithium. Identifying the drug cause is critical because symptoms may be reversible with medication discontinuation, unlike idiopathic Parkinson's disease.

Documentation Requirements

  • Specific non-neuroleptic medication identified as the cause
  • Temporal relationship between drug exposure and symptom development
  • Parkinsonian features documented on examination
  • Provider statement attributing symptoms to the medication
  • Adverse effect T-code coded for the specific medication
  • Plan for medication adjustment or discontinuation

Use Additional Code

  • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)

Commonly Confused Codes

  • G21.11: Neuroleptic induced parkinsonism: specifically for antipsychotic medications
  • G20.A1-G20.C: Parkinson's disease: idiopathic, not drug-induced
  • G25.1: Drug-induced tremor: tremor alone without full parkinsonian syndrome
  • G21.2: Secondary parkinsonism due to other external agents: for non-drug causes like toxins

Child Codes

Code Hierarchy

Because G21.19 maps to a payment HCC, the documentation must also satisfy MEAT criteria (Monitor, Evaluate, Assess, or Treat) for the encounter to count toward the patient's risk adjustment score.

Work G21.19 in HCC Buddy

Open G21.19 in the Code Book for the full Index-to-Tabular path, MEAT checklist, and V28 HCC mapping, or in the Encoder to code from a keyword search. Pro includes 14 days to try everything.