E26.1 ICD-10-CM Code: Secondary hyperaldosteronism
E26.1 is not a CMS-HCC payment code. MEAT criteria · RAF Calculator · HCC coding software
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FY 2026 Apr update / Endocrine, nutritional and metabolic diseases (E00-E89) / Disorders of other endocrine glands (E20-E35)
E26.1
Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidanceSecondary hyperaldosteronism
Excessive aldosterone production caused by kidney disease, heart failure, liver disease, or other secondary conditions rather than a primary adrenal problem.
Buddy Insight
Secondary hyperaldosteronism is a compensatory elevation in aldosterone production driven by activation of the renin-angiotensin-aldosterone system from conditions causing reduced renal perfusion.
CMS-HCC V28
N/A—
Not mapped
CMS-HCC V24
HistoricalHistorical
Not used for CY2026 payment
ACA/HHS
MappedHCC 030
Code-level coefficient reference
ESRD/PACE
MappedHCC 23
Code-level coefficient reference
RXHCC
MappedHCC 43
Code-level coefficient reference
Code Book Path
Inclusion Terms
OfficialNo inclusion terms are included in this display for E26.1. Check the code and parent instructions in the Code Book.
Excludes 2
OfficialNo Excludes 2 notes are included in this display for E26.1. Check the code and parent instructions in the Code Book.
Related Codes
Includes
OfficialNo Includes notes are included in this display for E26.1. Check the code and parent instructions in the Code Book.
Excludes 1
Official- transitory endocrine and metabolic disorders specific to newborn (P70-P74)Inherited from E00-E89, E20-E35
- galactorrhea (N64.3)Inherited from E00-E89, E20-E35
- gynecomastia (N62)Inherited from E00-E89, E20-E35
Code First
OfficialNo Code First sequencing instructions are included in this display for E26.1. Check the code and parent instructions in the Code Book.
Use Additional
OfficialNo Use Additional Code instructions are included in this display for E26.1. Check the code and parent instructions in the Code Book.
Code Also
OfficialNo Code Also instructions are included in this display for E26.1. Check the code and parent instructions in the Code Book.
Buddy Documentation Tip
MEAT Support
Audit Caution
Common Mistakes
Current with CMS: FY2026 ICD-10-CM Apr 1 update (effective Apr 1 – Sep 30, 2026) · CMS-HCC V28, 100% phased in for payment year 2026. FY2027 code set already staged for October 1, 2026. How HCC Buddy stays current →
Is E26.1 an HCC code?
E26.1 is not in the CMS-HCC V28 or V24 community payment model. E26.1 has a separate mapping under the CMS-HCC ESRD model (HCC 23 (Other Significant Endocrine and Metabolic Disorders)) and the Part D RxHCC model (HCC 43 (Pituitary, Adrenal Gland, and Other Endocrine and Metabolic Disorders)); the applicable result needs member context. E26.1 also appears in the HHS-HCC commercial risk model (HCC 030 (HHS-HCC 030 adult, RAF varies by metal level)), which is a commercial market model rather than a Medicare Advantage payment mapping.
- Code
- E26.1
- Description
- Secondary hyperaldosteronism
- HCC (V28)
- No CMS-HCC V28 mapping
- RAF reference coefficient
- —
- Billable
- Yes
- Payment year
- 2026
HCC Category Mapping
These are source-labeled model coefficients, not member totals. A category may still be removed by hierarchy or model cleanup rules. Weights are not directly comparable across models: CMS-HCC V28 and V24 use Community, Non-Dual, Aged; ESRD uses the dialysis continuing-enrollee model; RxHCC is the Part D continuing-enrollee, non-low-income, aged weight (a larger scale than CMS-HCC). ACA/HHS has no single weight — it varies by metal level. Actual per-patient RAF contribution depends on member context, hierarchy and cleanup rules, interactions, and the model year used by the payer. V28 is the CMS-HCC model phased in over payment years 2024–2026; V24 remains available for historical review.
Work E26.1 in the Code Book — tabular path, V28 RAF reference, and MEAT checklist →
MEAT review for E26.1
For E26.1, confirm that the documentation supports the diagnosis and meets the applicable coding, encounter, program and payer requirements. MEAT (Monitor, Evaluate, Assess, or Treat) is a review mnemonic, not a universal CMS coding rule.
- MMonitor: signs, symptoms, disease progression, or lab trending documented in the note
- EEvaluate: test results, medication response, or physical findings reviewed by the provider
- AAssess: explicit mention in the assessment or plan with acknowledgment of status
- TTreat: medication, referral, procedure, therapy, or counseling tied to the diagnosis
Coder workflow notes
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What This Code Means
E26.1 is the ICD-10-CM diagnosis code for secondary hyperaldosteronism. Excessive aldosterone production caused by kidney disease, heart failure, liver disease, or other secondary conditions rather than a primary adrenal problem. E26.1 sits in the ICD-10-CM chapter for endocrine, nutritional and metabolic diseases (e00-e89), within the section covering disorders of other endocrine glands (e20-e35).
E26.1 has no mapping under the CMS-HCC V28 or V24 community payment models. E26.1 has a separate mapping under the CMS-HCC ESRD model (HCC 23 (Other Significant Endocrine and Metabolic Disorders)) and the Part D RxHCC model (HCC 43 (Pituitary, Adrenal Gland, and Other Endocrine and Metabolic Disorders)); the applicable result needs member context. E26.1 also appears in the HHS-HCC commercial risk model (HCC 030 (HHS-HCC 030 adult, RAF varies by metal level)), which is a commercial market model rather than a Medicare Advantage payment mapping. Do not assign V28 risk adjustment value from this page; verify the applicable model and payment year before using this code for risk adjustment.
Always code the underlying cause (kidney disease, heart failure, etc.) as an additional diagnosis.
HCC Buddy maintains structured V28 and V24 mapping, source-labeled coefficient references, and MEAT documentation criteria for E26.1 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.
Coding Tips
- •Always code the underlying cause (kidney disease, heart failure, etc.) as an additional diagnosis
- •Distinguish from primary hyperaldosteronism (E26.0x) which has different treatment approaches
Clinical Significance
Secondary hyperaldosteronism is a compensatory elevation in aldosterone production driven by activation of the renin-angiotensin-aldosterone system from conditions causing reduced renal perfusion. Common causes include heart failure, cirrhosis, nephrotic syndrome, and renal artery stenosis, where the aldosterone elevation is an appropriate physiologic response rather than primary gland pathology.
Documentation Requirements
- ✓Document the underlying cause (heart failure, cirrhosis, renal artery stenosis, nephrotic syndrome), renin and aldosterone levels (both elevated in secondary form), potassium levels, and treatment directed at the underlying condition.