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D75.A ICD-10-CM Code: Glucose-6-phosphate dehydrogenase (G6PD) deficiency without anemia

D75.A is not a CMS-HCC payment code. MEAT criteria · RAF calculator · free HCC coding tools

ICD-10-CM Code View

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FY 2026 Apr update / Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89) / Other disorders of blood and blood-forming organs (D70-D77)

D75.A

Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidance

Glucose-6-phosphate dehydrogenase (G6PD) deficiency without anemia

A genetic enzyme deficiency that makes red blood cells fragile but does not currently cause anemia.

CMS-HCC V28

N/A

Not mapped

CMS-HCC V24

N/A

Not mapped

ACA/HHS

N/A

Not mapped

ESRD/PACE

N/A

Not mapped

RXHCC

N/A

Not mapped

Code Book Path

Official
D75Other and unspecified diseases of blood and blood-forming organs
D75.AGlucose-6-phosphate dehydrogenase (G6PD) deficiency without anemia

Inclusion Terms

Official

ICD-10-CM does not list inclusion terms for D75.A in this effective period.

Excludes 2

Official
  • acute lymphadenitis (L04.-)
  • chronic lymphadenitis (I88.1)
  • enlarged lymph nodes (R59.-)
  • hypergammaglobulinemia NOS (D89.2)
  • lymphadenitis NOS (I88.9)

Related Child Codes

Official
D75.0Familial erythrocytosis
D75.1Secondary polycythemia
D75.8Other specified diseases of blood and blood-forming organs
D75.9Disease of blood and blood-forming organs, unspecified

Includes

Official

ICD-10-CM does not list Includes notes for D75.A in this effective period.

Excludes 1

Official
  • glucose-6-phosphate dehydrogenase (G6PD) deficiency with anemia (D55.0)

Code First

Official

ICD-10-CM does not list Code First sequencing instructions for D75.A in this effective period.

Use Additional

Official

ICD-10-CM does not list Use Additional Code instructions for D75.A in this effective period.

Code Also

Official

ICD-10-CM does not list Code Also instructions for D75.A in this effective period.

Buddy Documentation Tip

HCC Buddy guidance
This code is specifically for G6PD deficiency WITHOUT anemia; use different codes if anemia is present
Document that the patient is at risk for hemolytic episodes if exposed to certain medications or foods

Current with CMS: FY2026 ICD-10-CM Apr 1 update (effective Apr 1 – Sep 30, 2026) · CMS-HCC V28, 100% phased in for payment year 2026. FY2027 code set already staged for October 1, 2026. How HCC Buddy stays current →

Is D75.A an HCC code?

No. D75.A is a billable ICD-10-CM code but does not map to any HCC category in V28, V24, ESRD, or RxHCC.

Code
D75.A
Description
Glucose-6-phosphate dehydrogenase (G6PD) deficiency without anemia
HCC (V28)
No CMS-HCC V28 mapping
RAF
Billable
Yes
Payment year
2026

Coder workflow notes

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This code does not map to an HCC category in any model (V28, V24, ESRD, RxHCC).

What This Code Means

D75.A is the ICD-10-CM diagnosis code for glucose-6-phosphate dehydrogenase (g6pd) deficiency without anemia. A genetic enzyme deficiency that makes red blood cells fragile but does not currently cause anemia. D75.A sits in the ICD-10-CM chapter for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (d50-d89), within the section covering other disorders of blood and blood-forming organs (d70-d77).

D75.A is a billable ICD-10-CM code but does not map to a payment HCC under the CMS-HCC V28, V24, ESRD, or RxHCC risk adjustment models. It can be reported on Medicare Advantage encounter data submissions but it does not contribute to a beneficiary's RAF score and therefore does not affect risk-adjusted payments to the plan.

This code is specifically for G6PD deficiency WITHOUT anemia; use different codes if anemia is present.

HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for D75.A sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Coding Tips

  • This code is specifically for G6PD deficiency WITHOUT anemia; use different codes if anemia is present
  • Document that the patient is at risk for hemolytic episodes if exposed to certain medications or foods

Excludes 1, Do NOT code together

  • glucose-6-phosphate dehydrogenase (G6PD) deficiency with anemia (D55.0)

Child Codes

Code Hierarchy

D75.A code history

Code setChange
FY2020 (effective Oct 1, 2019)Added to the code set

Source: official CMS ICD-10-CM order and addenda files, FY2016 through FY2027.

Work D75.A in HCC Buddy

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