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D75.828 ICD-10-CM Code: Other heparin-induced thrombocytopenia syndrome

D75.828 is not a CMS-HCC payment code. MEAT criteria · RAF calculator · HCC Buddy coding tools

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FY 2026 Apr update / Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89) / Other disorders of blood and blood-forming organs (D70-D77)

D75.828

Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidance

Other heparin-induced thrombocytopenia syndrome

Other specified types of heparin-induced thrombocytopenia that don't fit into the standard immune or non-immune categories.

Buddy the Bee presenting code insight

Buddy Insight

Other heparin-induced thrombocytopenia syndrome represents atypical presentations of platelet-mediated immune responses to heparin that do not fit the classic immune-mediated (type II) or non-immune (type I) classification.

CMS-HCC V28

N/A

Not mapped

CMS-HCC V24

HCC 48

RAF 0.192

ACA/HHS

HCC 75

Varies by metal level

ESRD/PACE

HCC 48

RAF 0.063

RXHCC

N/A

Not mapped

Code Book Path

Official
D75.8Other specified diseases of blood and blood-forming organs
D75.82Heparin induced thrombocytopenia (HIT)
D75.828Other heparin-induced thrombocytopenia syndrome

Inclusion Terms

Official
  • Autoimmune heparin-induced thrombocytopenia syndrome
  • Delayed-onset heparin-induced thrombocytopenia
  • Persisting heparin-induced thrombocytopenia

Excludes 2

Official

ICD-10-CM does not list Excludes 2 notes for D75.828 in this effective period.

Related Child Codes

Official
D75.821Non-immune heparin-induced thrombocytopenia
D75.822Immune-mediated heparin-induced thrombocytopenia
D75.829Heparin-induced thrombocytopenia, unspecified

Includes

Official

ICD-10-CM does not list Includes notes for D75.828 in this effective period.

Excludes 1

Official

ICD-10-CM does not list Excludes 1 notes for D75.828 in this effective period.

Code First

Official

ICD-10-CM does not list Code First sequencing instructions for D75.828 in this effective period.

Use Additional

Official
  • code, if applicable, for adverse effect of heparin (T45.515-)

Code Also

Official

ICD-10-CM does not list Code Also instructions for D75.828 in this effective period.

Buddy Documentation Tip

HCC Buddy guidance
Documentation must specify the atypical mechanism or presentation distinguishing this from immune-mediated (D75.821) or non-immune (D75.822) heparin-induced thrombocytopenia.
Include platelet count trends with nadir values, timing relative to heparin exposure, anti-platelet factor 4 antibody test results, and the specific clinical rationale for classifying this as an 'other' type.
Document current and alternative anticoagulation therapy.

MEAT Support

HCC Buddy guidance
Documentation must specify the atypical mechanism or presentation distinguishing this from immune-mediated (D75.821) or non-immune (D75.822) heparin-induced thrombocytopenia.
Include platelet count trends with nadir values, timing relative to heparin exposure, anti-platelet factor 4 antibody test results, and the specific clinical rationale for classifying this as an 'other' type.
Document current and alternative anticoagulation therapy.

Audit Caution

HCC Buddy guidance
Do not default to this code simply because the documentation is vague
query the provider for immune vs. non-immune status first. Ensure that the thrombocytopenia is directly linked to heparin exposure and not attributable to other causes such as sepsis-induced thrombocytopenia or disseminated intravascular coagulation. An adverse effect code (T45.515A) for heparin should also be assigned.

Common Mistakes

HCC Buddy guidance
D75.821 (heparin-induced thrombocytopenia, immune-mediated type II, which involves anti-PF4 antibodies), D75.822 (non-immune heparin-induced thrombocytopenia, type I, which is benign and self-limiting), D75.829 (unspecified heparin-induced thrombocytopenia when type cannot be determined), D69.59 (other secondary thrombocytopenia not related to heparin).

Current with CMS: FY2026 ICD-10-CM Apr 1 update (effective Apr 1 – Sep 30, 2026) · CMS-HCC V28, 100% phased in for payment year 2026. FY2027 code set already staged for October 1, 2026. How HCC Buddy stays current →

Is D75.828 an HCC code?

Yes. D75.828 maps to Coagulation Defects and Other Specified Hematological Disorders under the V24 model but is not retained in V28.

Code
D75.828
Description
Other heparin-induced thrombocytopenia syndrome
HCC (V28)
No CMS-HCC V28 mapping
RAF
Billable
Yes
Payment year
2026

HCC Category Mapping

V24HCC 48, Coagulation Defects and Other Specified Hematological Disorders
0.192
ESRDHCC 48, Coagulation Defects and Other Specified Hematological Disorders
0.063

Each model's RAF is its CMS base weight for that model's standard population, so weights are not directly comparable across models: CMS-HCC V28 and V24 use Community, Non-Dual, Aged; ESRD uses the dialysis continuing-enrollee model; RxHCC is the Part D continuing-enrollee, non-low-income, aged weight (a larger scale than CMS-HCC). ACA/HHS has no single weight — it varies by metal level. Actual per-patient RAF contribution depends on member segment, interactions, and the model year used by the payer. V28 is the CMS-HCC model phased in over payment years 2024–2026; V24 remains in use during the transition and for historical data.

Work D75.828 in the Code Book — tabular path, V28 RAF, and MEAT checklist →

MEAT Criteria for D75.828

For D75.828 to count as a valid HCC diagnosis in a given encounter, the provider's documentation must show MEAT: Monitor, Evaluate, Assess, or Treat. A diagnosis from a prior year does not carry forward automatically, it has to be re-documented and supported each calendar year.

  • MMonitor: signs, symptoms, disease progression, or lab trending documented in the note
  • EEvaluate: test results, medication response, or physical findings reviewed by the provider
  • AAssess: explicit mention in the assessment or plan with acknowledgment of status
  • TTreat: medication, referral, procedure, therapy, or counseling tied to the diagnosis

Only one of M/E/A/T is required to support the code, but the documentation must be specific enough to show that the provider actually addressed D75.828 during that encounter, not just copy-forwarded from a problem list.

Coder workflow notes

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What This Code Means

D75.828 is the ICD-10-CM diagnosis code for other heparin-induced thrombocytopenia syndrome. Other specified types of heparin-induced thrombocytopenia that don't fit into the standard immune or non-immune categories. D75.828 sits in the ICD-10-CM chapter for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (d50-d89), within the section covering other disorders of blood and blood-forming organs (d70-d77).

Under the older CMS-HCC V24 model, D75.828 maps to Coagulation Defects and Other Specified Hematological Disorders (HCC 48) with a community, non-dual, aged base RAF weight of 0.192. V28 is the CMS-HCC risk adjustment model that reached 100% phase-in for payment year 2026, replacing V24 which was used during the PY2024–PY2025 transition.

Use this code only when the specific type of HIT is documented but doesn't match D75.821 or D75.822. Because D75.828 maps to a payment HCC, the provider's documentation must satisfy MEAT criteria (Monitor, Evaluate, Assess, or Treat) for the encounter to count toward the patient's Medicare Advantage risk adjustment score. When documentation is ambiguous, coders should issue a provider query rather than assume the highest-specificity variant.

HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for D75.828 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Coding Tips

  • Use this code only when the specific type of HIT is documented but doesn't match D75.821 or D75.822
  • Include documentation of the atypical presentation or mechanism in the medical record

Clinical Significance

Other heparin-induced thrombocytopenia syndrome represents atypical presentations of platelet-mediated immune responses to heparin that do not fit the classic immune-mediated (type II) or non-immune (type I) classification. These variants can still carry significant thrombotic risk and require careful hematologic management including immediate heparin cessation and alternative anticoagulation.

Documentation Requirements

  • Documentation must specify the atypical mechanism or presentation distinguishing this from immune-mediated (D75.821) or non-immune (D75.822) heparin-induced thrombocytopenia.
  • Include platelet count trends with nadir values, timing relative to heparin exposure, anti-platelet factor 4 antibody test results, and the specific clinical rationale for classifying this as an 'other' type.
  • Document current and alternative anticoagulation therapy.

Commonly Confused Codes

  • D75.821 (heparin-induced thrombocytopenia, immune-mediated type II, which involves anti-PF4 antibodies), D75.822 (non-immune heparin-induced thrombocytopenia, type I, which is benign and self-limiting), D75.829 (unspecified heparin-induced thrombocytopenia when type cannot be determined), D69.59 (other secondary thrombocytopenia not related to heparin).

Child Codes

Code Hierarchy

D75.828 code history

Code setChange
FY2023 (effective Oct 1, 2022)Added to the code set

Source: official CMS ICD-10-CM order and addenda files, FY2016 through FY2027.

Because D75.828 maps to a payment HCC, the documentation must also satisfy MEAT criteria (Monitor, Evaluate, Assess, or Treat) for the encounter to count toward the patient's risk adjustment score.

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