D75.822 ICD-10-CM Code: Immune-mediated heparin-induced thrombocytopenia
D75.822 is not a CMS-HCC payment code. MEAT criteria · RAF calculator · HCC Buddy coding tools
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FY 2026 Apr update / Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89) / Other disorders of blood and blood-forming organs (D70-D77)
D75.822
Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidanceImmune-mediated heparin-induced thrombocytopenia
An immune system reaction to heparin medication that causes a severe drop in platelet count and increased risk of blood clots.
Buddy Insight
Immune-mediated heparin-induced thrombocytopenia (HIT Type II) is a serious prothrombotic condition caused by antibodies against platelet factor 4-heparin complexes.
CMS-HCC V28
N/A—
Not mapped
CMS-HCC V24
MappedHCC 48
RAF 0.192
ACA/HHS
MappedHCC 75
Varies by metal level
ESRD/PACE
MappedHCC 48
RAF 0.063
RXHCC
N/A—
Not mapped
Code Book Path
Inclusion Terms
Official- Immune-mediated HIT
- Type 2 heparin-induced thrombocytopenia
Excludes 2
OfficialICD-10-CM does not list Excludes 2 notes for D75.822 in this effective period.
Related Child Codes
Includes
OfficialICD-10-CM does not list Includes notes for D75.822 in this effective period.
Excludes 1
OfficialICD-10-CM does not list Excludes 1 notes for D75.822 in this effective period.
Code First
OfficialICD-10-CM does not list Code First sequencing instructions for D75.822 in this effective period.
Use Additional
Official- code, if applicable, for adverse effect of heparin (T45.515-)
Code Also
OfficialICD-10-CM does not list Code Also instructions for D75.822 in this effective period.
Buddy Documentation Tip
MEAT Support
Audit Caution
Common Mistakes
Current with CMS: FY2026 ICD-10-CM Apr 1 update (effective Apr 1 – Sep 30, 2026) · CMS-HCC V28, 100% phased in for payment year 2026. FY2027 code set already staged for October 1, 2026. How HCC Buddy stays current →
Is D75.822 an HCC code?
Yes. D75.822 maps to Coagulation Defects and Other Specified Hematological Disorders under the V24 model but is not retained in V28.
- Code
- D75.822
- Description
- Immune-mediated heparin-induced thrombocytopenia
- HCC (V28)
- No CMS-HCC V28 mapping
- RAF
- —
- Billable
- Yes
- Payment year
- 2026
HCC Category Mapping
Each model's RAF is its CMS base weight for that model's standard population, so weights are not directly comparable across models: CMS-HCC V28 and V24 use Community, Non-Dual, Aged; ESRD uses the dialysis continuing-enrollee model; RxHCC is the Part D continuing-enrollee, non-low-income, aged weight (a larger scale than CMS-HCC). ACA/HHS has no single weight — it varies by metal level. Actual per-patient RAF contribution depends on member segment, interactions, and the model year used by the payer. V28 is the CMS-HCC model phased in over payment years 2024–2026; V24 remains in use during the transition and for historical data.
Work D75.822 in the Code Book — tabular path, V28 RAF, and MEAT checklist →
MEAT Criteria for D75.822
For D75.822 to count as a valid HCC diagnosis in a given encounter, the provider's documentation must show MEAT: Monitor, Evaluate, Assess, or Treat. A diagnosis from a prior year does not carry forward automatically, it has to be re-documented and supported each calendar year.
- MMonitor: signs, symptoms, disease progression, or lab trending documented in the note
- EEvaluate: test results, medication response, or physical findings reviewed by the provider
- AAssess: explicit mention in the assessment or plan with acknowledgment of status
- TTreat: medication, referral, procedure, therapy, or counseling tied to the diagnosis
Only one of M/E/A/T is required to support the code, but the documentation must be specific enough to show that the provider actually addressed D75.822 during that encounter, not just copy-forwarded from a problem list.
Coder workflow notes
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What This Code Means
D75.822 is the ICD-10-CM diagnosis code for immune-mediated heparin-induced thrombocytopenia. An immune system reaction to heparin medication that causes a severe drop in platelet count and increased risk of blood clots. D75.822 sits in the ICD-10-CM chapter for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (d50-d89), within the section covering other disorders of blood and blood-forming organs (d70-d77).
Under the older CMS-HCC V24 model, D75.822 maps to Coagulation Defects and Other Specified Hematological Disorders (HCC 48) with a community, non-dual, aged base RAF weight of 0.192. V28 is the CMS-HCC risk adjustment model that reached 100% phase-in for payment year 2026, replacing V24 which was used during the PY2024–PY2025 transition.
This is the more common form of HIT; ensure immune mechanism is documented before coding this instead of D75.821. Because D75.822 maps to a payment HCC, the provider's documentation must satisfy MEAT criteria (Monitor, Evaluate, Assess, or Treat) for the encounter to count toward the patient's Medicare Advantage risk adjustment score. When documentation is ambiguous, coders should issue a provider query rather than assume the highest-specificity variant.
HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for D75.822 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.
Coding Tips
- •This is the more common form of HIT; ensure immune mechanism is documented before coding this instead of D75.821
- •Document any thrombotic complications that may have occurred as a result of immune HIT
Clinical Significance
Immune-mediated heparin-induced thrombocytopenia (HIT Type II) is a serious prothrombotic condition caused by antibodies against platelet factor 4-heparin complexes. Despite causing thrombocytopenia, HIT paradoxically increases thrombotic risk, with up to 50% of untreated patients developing arterial or venous thrombosis. Immediate heparin cessation and initiation of alternative anticoagulation (argatroban, bivalirudin, fondaparinux) is mandatory.
Documentation Requirements
- ✓Document platelet count decline of >50% from baseline occurring 5-10 days after heparin exposure (or within 1 day if prior heparin exposure within 100 days), positive HIT antibody testing (PF4-ELISA and/or serotonin release assay), and 4Ts score.
- ✓Record all heparin products discontinued (including flushes), alternative anticoagulant initiated, and any thrombotic complications.