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D56.8

Billable

Other thalassemias

HCC Category Mapping

V24HCC 48Coagulation Defects and Other Specified Hematological Disorders
0.209
ESRDHCC 48Coagulation Defects and Other Specified Hematological Disorders
0.000

What This Code Means

A group of inherited blood disorders affecting hemoglobin production that don't fit into the more specific thalassemia categories, causing varying degrees of anemia.

Coding Tips

  • Use this code only when the thalassemia type is documented but doesn't match D56.0-D56.5 categories
  • Review documentation for alpha thalassemia variants, delta thalassemia, or other rare forms

Clinical Significance

This code captures thalassemia variants that do not fit specific subcategories including delta thalassemia, epsilon thalassemia, and other rare hemoglobin chain production disorders. These conditions vary in clinical severity from asymptomatic to moderately symptomatic with chronic anemia. While individually rare, accurate coding is important for distinguishing from more common thalassemia types and ensuring appropriate genetic counseling.

Documentation Requirements

  • Document the specific thalassemia variant identified through hemoglobin electrophoresis, molecular genetic testing, or other laboratory studies.
  • Record why the condition does not fit into D56.0-D56.5 categories.
  • Include hemoglobin levels, mean corpuscular volume, evidence of hemolysis if present, transfusion requirements, and management plan.
  • Family history and genetic counseling documentation should be included.

Excludes 1 — Do NOT code together

  • hemoglobin C disease (D58.2)
  • hemoglobin E disease (D58.2)
  • other hemoglobinopathies (D58.2)
  • sickle-cell anemia (D57.-)
  • sickle-cell thalassemia (D57.4-)

Commonly Confused Codes

Code Hierarchy

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