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C53 ICD-10-CM Code: Malignant neoplasm of cervix uteri

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FY 2026 Apr update / Neoplasms (C00-D49) / Malignant neoplasms of female genital organs (C51-C58)

C53

Header CodeICD-10-CMOfficial ICD-10-CMCodebook guidance

Malignant neoplasm of cervix uteri

Malignant neoplasm of cervix uteri

CMS-HCC V28

0

0

RAF 0

CMS-HCC V24

0

0

RAF 0

ACA/HHS

0

0

RAF 0

ESRD/PACE

0

0

RAF 0

RXHCC

0

0

RAF 0

Code Trumping

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Code Book Path

Official
C5Malignant neoplasms of female genital organs (C51-C58)
C53Malignant neoplasm of cervix uteri

Inclusion Terms

Official

ICD-10-CM does not list inclusion terms for C53 in this effective period.

Excludes 2

Official

ICD-10-CM does not list Excludes 2 notes for C53 in this effective period.

Related Child Codes

Official
C53.0Malignant neoplasm of endocervix
C53.1Malignant neoplasm of exocervix
C53.8Malignant neoplasm of overlapping sites of cervix uteri
C53.9Malignant neoplasm of cervix uteri, unspecified

Includes

Official

ICD-10-CM does not list Includes notes for C53 in this effective period.

Excludes 1

Official
  • carcinoma in situ of cervix uteri (D06.-)

Code First

Official

ICD-10-CM does not list Code First sequencing instructions for C53 in this effective period.

Use Additional

Official

ICD-10-CM does not list Use Additional Code instructions for C53 in this effective period.

Code Also

Official

ICD-10-CM does not list Code Also instructions for C53 in this effective period.

Last updated: FY2026 ICD-10-CM Apr update, Apr 1, 2026 through Sep 30, 2026. CMS-HCC V28 is 100% phased in for payment year 2026.

What This Code Means

C53 is the ICD-10-CM diagnosis code for malignant neoplasm of cervix uteri. C53 sits in the ICD-10-CM chapter for neoplasms (c00-d49), within the section covering malignant neoplasms of female genital organs (c51-c58).

Header codes like C53 cannot be reported on claims directly, they organize child codes that share clinical context but the actual diagnosis must be coded to the highest level of specificity supported by the documentation. Coders should look at C53's child codes and select the one that matches the patient's documented presentation, since payers reject header codes submitted as the primary diagnosis. For risk adjustment workflows, header codes never contribute to a Medicare Advantage member's RAF score on their own; only billable child codes that happen to map to a payment HCC affect risk-adjusted plan payments.

HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for C53 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Excludes 1, Do NOT code together

  • carcinoma in situ of cervix uteri (D06.-)

Child Codes

Code Hierarchy

C53Malignant neoplasm of cervix uteri
C53Malignant neoplasm of cervix uteri

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