B00.4 ICD-10-CM Code: Herpesviral encephalitis
HCC Buddy Code Card
Digital ICD-10 code-book layout with official code detail, always-visible risk models, Code Trumping, and Buddy coding guidance.
FY 2026 Apr update / Certain infectious and parasitic diseases (A00-B99) / Viral infections characterized by skin and mucous membrane lesions (B00-B09)
B00.4
Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidanceHerpesviral encephalitis
A serious brain infection caused by herpes simplex virus that can cause fever, confusion, seizures, and altered consciousness.
CMS-HCC V28
00
RAF 0
CMS-HCC V24
00
RAF 0
ACA/HHS
00
RAF 0
ESRD/PACE
00
RAF 0
RXHCC
00
RAF 0
Code Trumping
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Code Book Path
Inclusion Terms
Official- Herpesviral meningoencephalitis
- Simian B disease
Excludes 2
Official- anogenital herpesviral infection (A60.-)
- gammaherpesviral mononucleosis (B27.0-)
- herpangina (B08.5)
Related Child Codes
Includes
OfficialICD-10-CM does not list Includes notes for B00.4 in this effective period.
Excludes 1
Official- herpesviral encephalitis due to herpesvirus 6 and 7 (B10.01, B10.09)
- non-simplex herpesviral encephalitis (B10.0-)
Code First
OfficialICD-10-CM does not list Code First sequencing instructions for B00.4 in this effective period.
Use Additional
OfficialICD-10-CM does not list Use Additional Code instructions for B00.4 in this effective period.
Code Also
OfficialICD-10-CM does not list Code Also instructions for B00.4 in this effective period.
Buddy Documentation Tip
Last updated: FY2026 ICD-10-CM Apr update, Apr 1, 2026 through Sep 30, 2026. CMS-HCC V28 is 100% phased in for payment year 2026.
Is B00.4 an HCC code?
No. B00.4 is a billable ICD-10-CM code but does not map to any HCC category in V28, V24, ESRD, or RxHCC.
This code does not map to an HCC category in any model (V28, V24, ESRD, RxHCC).
What This Code Means
B00.4 is the ICD-10-CM diagnosis code for herpesviral encephalitis. A serious brain infection caused by herpes simplex virus that can cause fever, confusion, seizures, and altered consciousness. B00.4 sits in the ICD-10-CM chapter for certain infectious and parasitic diseases (a00-b99), within the section covering viral infections characterized by skin and mucous membrane lesions (b00-b09).
B00.4 is a billable ICD-10-CM code but does not map to a payment HCC under the CMS-HCC V28, V24, ESRD, or RxHCC risk adjustment models. It can be reported on Medicare Advantage encounter data submissions but it does not contribute to a beneficiary's RAF score and therefore does not affect risk-adjusted payments to the plan.
This is a medical emergency; verify encephalitis is clearly documented.
HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for B00.4 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.
Coding Tips
- •This is a medical emergency; verify encephalitis is clearly documented
- •Distinguish from meningitis (B00.3) - encephalitis involves brain tissue inflammation