Skip to content

B10.01 ICD-10-CM Code: Human herpesvirus 6 encephalitis

B10.01 is not a CMS-HCC payment code. MEAT criteria · RAF Calculator · HCC Buddy coding tools

ICD-10-CM Code View

HCC Buddy Code Card

Digital ICD-10 code-book layout with official code detail, always-visible risk models, Code Trumping, and Buddy coding guidance.

Code lookupB10.01

FY 2026 Apr update / Certain infectious and parasitic diseases (A00-B99) / Other human herpesviruses (B10)

B10.01

Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidance

Human herpesvirus 6 encephalitis

An infection caused by human herpesvirus 6 that causes inflammation of the brain.

CMS-HCC V28

N/A

Not mapped

CMS-HCC V24

Historical

Historical

Not used for CY2026 payment

ACA/HHS

HCC 003

Code-level coefficient reference

ESRD/PACE

N/A

Not mapped

RXHCC

N/A

Not mapped

Inclusion Terms

Official

No inclusion terms are included in this display for B10.01. Check the code and parent instructions in the Code Book.

Excludes 2

Official
  • carrier or suspected carrier of infectious disease (Z22.-)Inherited from A00-B99, B10, B10.0
  • infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium (O98.-)Inherited from A00-B99, B10, B10.0
  • infectious and parasitic diseases specific to the perinatal period (P35-P39)Inherited from A00-B99, B10, B10.0
  • influenza and other acute respiratory infections (J00-J22)Inherited from A00-B99, B10, B10.0
  • cytomegalovirus (B25.9)Inherited from A00-B99, B10, B10.0
  • Epstein-Barr virus (B27.0-)Inherited from A00-B99, B10, B10.0
  • herpes NOS (B00.9)Inherited from A00-B99, B10, B10.0
  • herpes simplex (B00.-)Inherited from A00-B99, B10, B10.0
  • herpes zoster (B02.-)Inherited from A00-B99, B10, B10.0
  • human herpesvirus NOS (B00.-)Inherited from A00-B99, B10, B10.0
  • human herpesvirus 1 and 2 (B00.-)Inherited from A00-B99, B10, B10.0
  • human herpesvirus 3 (B01.-, B02.-)Inherited from A00-B99, B10, B10.0
  • human herpesvirus 4 (B27.0-)Inherited from A00-B99, B10, B10.0
  • human herpesvirus 5 (B25.-)Inherited from A00-B99, B10, B10.0
  • varicella (B01.-)Inherited from A00-B99, B10, B10.0
  • zoster (B02.-)Inherited from A00-B99, B10, B10.0
  • herpes encephalitis NOS (B00.4)Inherited from A00-B99, B10, B10.0
  • herpes simplex encephalitis (B00.4)Inherited from A00-B99, B10, B10.0
  • human herpesvirus encephalitis (B00.4)Inherited from A00-B99, B10, B10.0
  • simian B herpes virus encephalitis (B00.4)Inherited from A00-B99, B10, B10.0

Includes

Official
  • diseases generally recognized as communicable or transmissibleInherited from A00-B99

Excludes 1

Official
  • certain localized infections - see body system-related chaptersInherited from A00-B99

Code First

Official

No Code First sequencing instructions are included in this display for B10.01. Check the code and parent instructions in the Code Book.

Use Additional

Official
  • code to identify resistance to antimicrobial drugs (Z16.-)Inherited from A00-B99

Code Also

Official

No Code Also instructions are included in this display for B10.01. Check the code and parent instructions in the Code Book.

Buddy Documentation Tip

HCC Buddy guidance
Ensure documentation clearly states HHV-6 as the causative agent and confirms encephalitis diagnosis
This is a serious condition; verify appropriate severity documentation and any complications

Current with CMS: FY2026 ICD-10-CM Apr 1 update (effective Apr 1 – Sep 30, 2026) · CMS-HCC V28, 100% phased in for payment year 2026. FY2027 code set already staged for October 1, 2026. How HCC Buddy stays current →

Is B10.01 an HCC code?

B10.01 is not in the CMS-HCC V28 or V24 community payment model. B10.01 also appears in the HHS-HCC commercial risk model (HCC 003 (HHS-HCC 003 adult, RAF varies by metal level)), which is a commercial market model rather than a Medicare Advantage payment mapping.

Code
B10.01
Description
Human herpesvirus 6 encephalitis
HCC (V28)
No CMS-HCC V28 mapping
RAF reference coefficient
Billable
Yes
Payment year
2026

Coder workflow notes

Get the V28 mapping + MEAT cheat sheet

One printable reference: check representative V28 mappings and the documentation reminders your note needs. Free, no card.

Free PDF. No card. Unsubscribe anytime.

This code does not map to an HCC category in any model (V28, V24, ESRD, RxHCC).

What This Code Means

B10.01 is the ICD-10-CM diagnosis code for human herpesvirus 6 encephalitis. An infection caused by human herpesvirus 6 that causes inflammation of the brain. B10.01 sits in the ICD-10-CM chapter for certain infectious and parasitic diseases (a00-b99), within the section covering other human herpesviruses (b10).

B10.01 has no mapping under the CMS-HCC V28 or V24 community payment models. B10.01 also appears in the HHS-HCC commercial risk model (HCC 003 (HHS-HCC 003 adult, RAF varies by metal level)), which is a commercial market model rather than a Medicare Advantage payment mapping. Do not assign V28 risk adjustment value from this page; verify the applicable model and payment year before using this code for risk adjustment.

Ensure documentation clearly states HHV-6 as the causative agent and confirms encephalitis diagnosis.

HCC Buddy maintains structured V28 and V24 mapping, source-labeled coefficient references, and MEAT documentation criteria for B10.01 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Coding Tips

  • Ensure documentation clearly states HHV-6 as the causative agent and confirms encephalitis diagnosis
  • This is a serious condition; verify appropriate severity documentation and any complications

Child Codes

Code Hierarchy

Work B10.01 in HCC Buddy

Open B10.01 in the Code Book for the full Index-to-Tabular path, MEAT checklist, and V28 HCC mapping, or in the Encoder to code from a keyword search. Pro includes 7 days to try everything, no card required.