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A49.1 ICD-10-CM Code: Streptococcal infection, unspecified site

A49.1 is not a CMS-HCC payment code. MEAT criteria · RAF Calculator · free HCC coding tools

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FY 2026 Apr update / Certain infectious and parasitic diseases (A00-B99) / Other bacterial diseases (A30-A49)

A49.1

Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidance

Streptococcal infection, unspecified site

A bacterial infection caused by streptococcus bacteria that has been identified but the specific location in the body where the infection occurs is not documented or specified. This is used when a streptococcal infection is confirmed but the site is unknown or not clearly documented.

CMS-HCC V28

N/A

Not mapped

CMS-HCC V24

Historical

Historical

Not used for CY2026 payment

ACA/HHS

N/A

Not mapped

ESRD/PACE

N/A

Not mapped

RXHCC

N/A

Not mapped

Code Book Path

Official
A49Bacterial infection of unspecified site
A49.1Streptococcal infection, unspecified site

Inclusion Terms

Official

ICD-10-CM does not list inclusion terms for A49.1 in this effective period.

Excludes 2

Official

ICD-10-CM does not list Excludes 2 notes for A49.1 in this effective period.

Related Child Codes

Official
A49.0Staphylococcal infection, unspecified site
A49.2Hemophilus influenzae infection, unspecified site
A49.3Mycoplasma infection, unspecified site
A49.8Other bacterial infections of unspecified site
A49.9Bacterial infection, unspecified

Includes

Official

ICD-10-CM does not list Includes notes for A49.1 in this effective period.

Excludes 1

Official
  • bacterial agents as the cause of diseases classified elsewhere (B95-B96)
  • chlamydial infection NOS (A74.9)
  • meningococcal infection NOS (A39.9)
  • rickettsial infection NOS (A79.9)
  • spirochetal infection NOS (A69.9)

Code First

Official

ICD-10-CM does not list Code First sequencing instructions for A49.1 in this effective period.

Use Additional

Official

ICD-10-CM does not list Use Additional Code instructions for A49.1 in this effective period.

Code Also

Official

ICD-10-CM does not list Code Also instructions for A49.1 in this effective period.

Buddy Documentation Tip

HCC Buddy guidance
Use this code only when the streptococcal infection site is truly unspecified; always query the provider if documentation indicates a specific anatomical location, as more specific codes (like A40 for sepsis or A41 for other sepsis) may be more appropriate
This code should not be used if the infection site can be determined from clinical documentation; review the medical record thoroughly for any indication of infection location (respiratory, urinary, skin, etc.) before assigning this unspecified code

Current with CMS: FY2026 ICD-10-CM Apr 1 update (effective Apr 1 – Sep 30, 2026) · CMS-HCC V28, 100% phased in for payment year 2026. FY2027 code set already staged for October 1, 2026. How HCC Buddy stays current →

Is A49.1 an HCC code?

No. A49.1 is a billable ICD-10-CM code with no mapping under the CMS-HCC V28 or V24 community payment models, and none under the ESRD, Part D RxHCC, or HHS-HCC models.

Code
A49.1
Description
Streptococcal infection, unspecified site
HCC (V28)
No CMS-HCC V28 mapping
RAF reference coefficient
Billable
Yes
Payment year
2026

Coder workflow notes

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This code does not map to an HCC category in any model (V28, V24, ESRD, RxHCC).

What This Code Means

A49.1 is the ICD-10-CM diagnosis code for streptococcal infection, unspecified site. A bacterial infection caused by streptococcus bacteria that has been identified but the specific location in the body where the infection occurs is not documented or specified. This is used when a streptococcal infection is confirmed but the site is unknown or not clearly documented. A49.1 sits in the ICD-10-CM chapter for certain infectious and parasitic diseases (a00-b99), within the section covering other bacterial diseases (a30-a49).

A49.1 is a billable ICD-10-CM code, but the current payload does not show a mapping under the CMS-HCC V28 or V24 community payment models, and none under the ESRD, Part D RxHCC, or HHS-HCC models. Do not assign risk adjustment value from this page when no source-backed mapping is shown; verify the applicable model and payment year.

Use this code only when the streptococcal infection site is truly unspecified; always query the provider if documentation indicates a specific anatomical location, as more specific codes (like A40 for sepsis or A41 for other sepsis) may be more appropriate.

HCC Buddy maintains structured V28 and V24 mapping, source-labeled coefficient references, and MEAT documentation criteria for A49.1 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Coding Tips

  • Use this code only when the streptococcal infection site is truly unspecified; always query the provider if documentation indicates a specific anatomical location, as more specific codes (like A40 for sepsis or A41 for other sepsis) may be more appropriate
  • This code should not be used if the infection site can be determined from clinical documentation; review the medical record thoroughly for any indication of infection location (respiratory, urinary, skin, etc.) before assigning this unspecified code

Child Codes

Code Hierarchy

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