R97.1
BillableElevated cancer antigen 125 [CA 125]
Last updated: FY2026 ICD-10-CM (Oct 1, 2025 – Sep 30, 2026) | CMS-HCC V28 (100% phase-in, PY2026)
Is R97.1 an HCC code?
No. R97.1 is a billable ICD-10-CM code but does not map to any HCC category in V28, V24, ESRD, or RxHCC.
This code does not map to an HCC category in any model (V28, V24, ESRD, RxHCC).
What This Code Means
R97.1 is the ICD-10-CM diagnosis code for elevated cancer antigen 125 [ca 125]. A blood test shows elevated levels of cancer antigen 125 (CA 125), a protein that can be associated with ovarian cancer or other conditions. R97.1 sits in the ICD-10-CM chapter for symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (r00-r99), within the section covering abnormal tumor markers (r97).
R97.1 is a billable ICD-10-CM code but does not map to a payment HCC under the CMS-HCC V28, V24, ESRD, or RxHCC risk adjustment models. It can be reported on Medicare Advantage encounter data submissions but it does not contribute to a beneficiary's RAF score and therefore does not affect risk-adjusted payments to the plan.
CA 125 elevation is not specific to cancer and can occur with benign conditions; document the clinical context.
HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for R97.1 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.
Coding Tips
- •CA 125 elevation is not specific to cancer and can occur with benign conditions; document the clinical context
- •Pair with specific cancer diagnosis codes if malignancy is confirmed