Question 1

What is ICD-10 code N46.121?

Accepted Answer

N46.121 is the ICD-10-CM diagnosis code for oligospermia due to drug therapy. Abnormally low sperm count caused by medications or drugs that reduce the testicles' ability to produce sperm. N46.121 sits in the ICD-10-CM chapter for diseases of the genitourinary system (n00-n99), within the section covering diseases of male genital organs (n40-n53).

N46.121 is a billable ICD-10-CM code but does not map to a payment HCC under the CMS-HCC V28, V24, ESRD, or RxHCC risk adjustment models. It can be reported on Medicare Advantage encounter data submissions but it does not contribute to a beneficiary's RAF score and therefore does not affect risk-adjusted payments to the plan.

Identify and document the specific medication causing the oligospermia.

Question 2

Is N46.121 an HCC code?

Accepted Answer

No. N46.121 is a billable ICD-10-CM code but does not map to any payment HCC category under the CMS-HCC V28, V24, ESRD, or RxHCC risk adjustment models. It can still be reported on Medicare Advantage encounter data submissions, but it does not contribute to the beneficiary's Risk Adjustment Factor (RAF) score and therefore does not affect the risk-adjusted capitation payment to the plan. V28 reached 100% phase-in for payment year 2026.

Question 3

Is N46.121 billable?

Accepted Answer

Yes. N46.121 is a billable ICD-10-CM code that can be reported on professional and institutional claims as a primary or secondary diagnosis when the provider documentation supports the specific condition described. Billable codes in ICD-10-CM are coded to the highest level of specificity available for the documented diagnosis. N46.121 is current for fiscal year 2026 and remains in the active CMS ICD-10-CM code set published by the National Center for Health Statistics.

Question 4

What is the V28 vs V24 difference for N46.121?

Accepted Answer

N46.121 does not map to a payment HCC under either the CMS-HCC V28 risk adjustment model or the older V24 model. V28 reached 100% phase-in for payment year 2026, replacing V24 which was used during the PY2024–PY2025 transition. Because neither model rewards N46.121 with a risk adjustment factor, it contributes zero to a Medicare Advantage beneficiary's RAF score in either version. Coders should check whether provider documentation supports a more specific child code that does map to a payment HCC.

Question 5

What should coders know when reporting N46.121?

Accepted Answer

Identify and document the specific medication causing the oligospermia Note whether the condition is expected to be reversible after medication discontinuation

N46.121

Is N46.121 an HCC code?

What This Code Means

Coding Tips

Code Hierarchy

Open N46.121 in the Interactive Encoder