Question 1

What is ICD-10 code N46.021?

Accepted Answer

N46.021 is the ICD-10-CM diagnosis code for azoospermia due to drug therapy. Complete absence of sperm in the ejaculate caused by medications or drugs that affect sperm production. N46.021 sits in the ICD-10-CM chapter for diseases of the genitourinary system (n00-n99), within the section covering diseases of male genital organs (n40-n53).

N46.021 is a billable ICD-10-CM code but does not map to a payment HCC under the CMS-HCC V28, V24, ESRD, or RxHCC risk adjustment models. It can be reported on Medicare Advantage encounter data submissions but it does not contribute to a beneficiary's RAF score and therefore does not affect risk-adjusted payments to the plan.

Document the specific drug causing the condition when possible for clinical correlation.

Question 2

Is N46.021 an HCC code?

Accepted Answer

No. N46.021 is a billable ICD-10-CM code but does not map to any payment HCC category under the CMS-HCC V28, V24, ESRD, or RxHCC risk adjustment models. It can still be reported on Medicare Advantage encounter data submissions, but it does not contribute to the beneficiary's Risk Adjustment Factor (RAF) score and therefore does not affect the risk-adjusted capitation payment to the plan. V28 reached 100% phase-in for payment year 2026.

Question 3

Is N46.021 billable?

Accepted Answer

Yes. N46.021 is a billable ICD-10-CM code that can be reported on professional and institutional claims as a primary or secondary diagnosis when the provider documentation supports the specific condition described. Billable codes in ICD-10-CM are coded to the highest level of specificity available for the documented diagnosis. N46.021 is current for fiscal year 2026 and remains in the active CMS ICD-10-CM code set published by the National Center for Health Statistics.

Question 4

What is the V28 vs V24 difference for N46.021?

Accepted Answer

N46.021 does not map to a payment HCC under either the CMS-HCC V28 risk adjustment model or the older V24 model. V28 reached 100% phase-in for payment year 2026, replacing V24 which was used during the PY2024–PY2025 transition. Because neither model rewards N46.021 with a risk adjustment factor, it contributes zero to a Medicare Advantage beneficiary's RAF score in either version. Coders should check whether provider documentation supports a more specific child code that does map to a payment HCC.

Question 5

What should coders know when reporting N46.021?

Accepted Answer

Document the specific drug causing the condition when possible for clinical correlation Consider if the condition is reversible upon discontinuation of the medication

N46.021

Is N46.021 an HCC code?

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Open N46.021 in the Interactive Encoder