N25.1

Billable

Nephrogenic diabetes insipidus

HCC Category Mapping

V24HCC 23 — Other Significant Endocrine and Metabolic Disorders

0.230

ESRDHCC 23 — Other Significant Endocrine and Metabolic Disorders

0.000

RxHCCHCC 43 — Other Significant Endocrine and Metabolic Disorders

0.000

What This Code Means

A kidney disorder where the kidneys cannot concentrate urine properly, causing excessive thirst and urination despite normal pituitary function.

Coding Tips

•Distinguish from central diabetes insipidus (E23.2) which is pituitary-related
•Document whether this is congenital or acquired for complete clinical picture

Clinical Significance

Nephrogenic diabetes insipidus represents kidney inability to concentrate urine despite normal pituitary function, leading to excessive urination and thirst. This rare condition requires specific management distinct from central diabetes insipidus and has meaningful HCC impact due to its complexity and treatment requirements.

Documentation Requirements

✓Nephrogenic diabetes insipidus specifically documented
✓Evidence of excessive urination and thirst
✓Normal or elevated ADH levels distinguishing from central DI
✓Kidney's inability to respond to ADH documented
✓Underlying cause identified if known (genetic, drug-induced, etc.)
✓Treatment plan including specific medications (amiloride, thiazides)
✓Monitoring for dehydration and electrolyte imbalances

Excludes 1 — Do NOT code together

diabetes insipidus NOS (E23.2)

Commonly Confused Codes

E23.2 — Diabetes insipidus (central diabetes insipidus, pituitary-related)R35.0 — Frequency of micturition (symptom, not specific diagnosis)E87.1 — Hypo-osmolality and hyponatremia (electrolyte abnormality)N28.89 — Other specified disorders of kidney and ureter (less specific)

Code Hierarchy

└N25Disorders resulting from impaired renal tubular function └N25.1Nephrogenic diabetes insipidus

└N25.1Nephrogenic diabetes insipidus