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N06.1 ICD-10-CM Code: Isolated proteinuria with focal and segmental glomerular lesions

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FY 2026 Apr update / Diseases of the genitourinary system (N00-N99) / Glomerular diseases (N00-N08)

N06.1

Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidance

Isolated proteinuria with focal and segmental glomerular lesions

A condition where protein is found in the urine with focal and segmental scarring or lesions in some of the kidney's filtering units, typically seen in focal segmental glomerulosclerosis.

CMS-HCC V28

N/A

Not mapped

CMS-HCC V24

N/A

Not mapped

ACA/HHS

N/A

Not mapped

ESRD/PACE

N/A

Not mapped

RXHCC

N/A

Not mapped

Code Book Path

Official
N06Isolated proteinuria with specified morphological lesion
N06.1Isolated proteinuria with focal and segmental glomerular lesions

Inclusion Terms

Official
  • Isolated proteinuria with focal and segmental hyalinosis
  • Isolated proteinuria with focal and segmental sclerosis
  • Isolated proteinuria with focal glomerulonephritis

Excludes 2

Official

ICD-10-CM does not list Excludes 2 notes for N06.1 in this effective period.

Related Child Codes

Official
N06.0Isolated proteinuria with minor glomerular abnormality
N06.2Isolated proteinuria with diffuse membranous glomerulonephritis
N06.3Isolated proteinuria with diffuse mesangial proliferative glomerulonephritis
N06.4Isolated proteinuria with diffuse endocapillary proliferative glomerulonephritis
N06.5Isolated proteinuria with diffuse mesangiocapillary glomerulonephritis

Includes

Official

ICD-10-CM does not list Includes notes for N06.1 in this effective period.

Excludes 1

Official
  • Proteinuria not associated with specific morphologic lesions (R80.0)

Code First

Official

ICD-10-CM does not list Code First sequencing instructions for N06.1 in this effective period.

Use Additional

Official

ICD-10-CM does not list Use Additional Code instructions for N06.1 in this effective period.

Code Also

Official

ICD-10-CM does not list Code Also instructions for N06.1 in this effective period.

Buddy Documentation Tip

HCC Buddy guidance
Focal and segmental pattern means only some glomeruli are affected and only portions of affected glomeruli show damage
Distinguish from diffuse patterns; pathology report should specify the percentage of glomeruli involved

Current with CMS: FY2026 ICD-10-CM Apr 1 update (effective Apr 1 – Sep 30, 2026) · CMS-HCC V28, 100% phased in for payment year 2026. FY2027 code set already staged for October 1, 2026. How HCC Buddy stays current →

Is N06.1 an HCC code?

No. N06.1 is a billable ICD-10-CM code but does not map to any HCC category in V28, V24, ESRD, or RxHCC.

Code
N06.1
Description
Isolated proteinuria with focal and segmental glomerular lesions
HCC (V28)
No CMS-HCC V28 mapping
RAF
Billable
Yes
Payment year
2026

Coder workflow notes

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This code does not map to an HCC category in any model (V28, V24, ESRD, RxHCC).

What This Code Means

N06.1 is the ICD-10-CM diagnosis code for isolated proteinuria with focal and segmental glomerular lesions. A condition where protein is found in the urine with focal and segmental scarring or lesions in some of the kidney's filtering units, typically seen in focal segmental glomerulosclerosis. N06.1 sits in the ICD-10-CM chapter for diseases of the genitourinary system (n00-n99), within the section covering glomerular diseases (n00-n08).

N06.1 is a billable ICD-10-CM code but does not map to a payment HCC under the CMS-HCC V28, V24, ESRD, or RxHCC risk adjustment models. It can be reported on Medicare Advantage encounter data submissions but it does not contribute to a beneficiary's RAF score and therefore does not affect risk-adjusted payments to the plan.

Focal and segmental pattern means only some glomeruli are affected and only portions of affected glomeruli show damage.

HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for N06.1 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Coding Tips

  • Focal and segmental pattern means only some glomeruli are affected and only portions of affected glomeruli show damage
  • Distinguish from diffuse patterns; pathology report should specify the percentage of glomeruli involved

Child Codes

Code Hierarchy

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