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H21.81 ICD-10-CM Code: Floppy iris syndrome

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FY 2026 Apr update / Diseases of the eye and adnexa (H00-H59) / Disorders of sclera, cornea, iris and ciliary body (H15-H22)

H21.81

Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidance

Floppy iris syndrome

A condition where the iris becomes abnormally floppy or loose during eye surgery, making it difficult to control during the procedure.

CMS-HCC V28

0

0

RAF 0

CMS-HCC V24

0

0

RAF 0

ACA/HHS

0

0

RAF 0

ESRD/PACE

0

0

RAF 0

RXHCC

0

0

RAF 0

Code Trumping

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Code Book Path

Official
H21Other disorders of iris and ciliary body
H21.8Other specified disorders of iris and ciliary body
H21.81Floppy iris syndrome

Inclusion Terms

Official
  • Intraoperative floppy iris syndrome (IFIS)

Excludes 2

Official

ICD-10-CM does not list Excludes 2 notes for H21.81 in this effective period.

Related Child Codes

Official
H21.82Plateau iris syndrome (post-iridectomy) (postprocedural)
H21.89Other specified disorders of iris and ciliary body

Includes

Official

ICD-10-CM does not list Includes notes for H21.81 in this effective period.

Excludes 1

Official

ICD-10-CM does not list Excludes 1 notes for H21.81 in this effective period.

Code First

Official

ICD-10-CM does not list Code First sequencing instructions for H21.81 in this effective period.

Use Additional

Official
  • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)

Code Also

Official

ICD-10-CM does not list Code Also instructions for H21.81 in this effective period.

Buddy Documentation Tip

HCC Buddy guidance
This is typically an intraoperative finding documented during cataract or other anterior segment surgery
Often associated with certain medications (alpha-blockers) or connective tissue disorders; review clinical documentation

Last updated: FY2026 ICD-10-CM Apr update, Apr 1, 2026 through Sep 30, 2026. CMS-HCC V28 is 100% phased in for payment year 2026.

Is H21.81 an HCC code?

No. H21.81 is a billable ICD-10-CM code but does not map to any HCC category in V28, V24, ESRD, or RxHCC.

Coder workflow notes

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This code does not map to an HCC category in any model (V28, V24, ESRD, RxHCC).

What This Code Means

H21.81 is the ICD-10-CM diagnosis code for floppy iris syndrome. A condition where the iris becomes abnormally floppy or loose during eye surgery, making it difficult to control during the procedure. H21.81 sits in the ICD-10-CM chapter for diseases of the eye and adnexa (h00-h59), within the section covering disorders of sclera, cornea, iris and ciliary body (h15-h22).

H21.81 is a billable ICD-10-CM code but does not map to a payment HCC under the CMS-HCC V28, V24, ESRD, or RxHCC risk adjustment models. It can be reported on Medicare Advantage encounter data submissions but it does not contribute to a beneficiary's RAF score and therefore does not affect risk-adjusted payments to the plan.

This is typically an intraoperative finding documented during cataract or other anterior segment surgery.

HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for H21.81 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Coding Tips

  • This is typically an intraoperative finding documented during cataract or other anterior segment surgery
  • Often associated with certain medications (alpha-blockers) or connective tissue disorders; review clinical documentation

Use Additional Code

  • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)

Child Codes

Code Hierarchy

Work H21.81 in HCC Buddy

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