E72.59
BillableOther disorders of glycine metabolism
HCC Category Mapping
V24HCC 23 — Other Significant Endocrine and Metabolic Disorders
0.230ESRDHCC 23 — Other Significant Endocrine and Metabolic Disorders
0.000RxHCCHCC 43 — Other Significant Endocrine and Metabolic Disorders
0.000What This Code Means
Other rare metabolic disorders affecting how the body processes glycine, an amino acid important for protein synthesis and nervous system function.
Coding Tips
- •Document the specific glycine metabolism disorder identified in the medical record
- •Ensure this code is used only when the disorder does not fit into more specific glycine metabolism codes
Clinical Significance
Other disorders of glycine metabolism captures specified glycine metabolism disorders that do not have their own unique ICD-10 code, such as sarcosinemia, hyperoxaluria type I (primary), or D-glyceric aciduria. These rare conditions can cause kidney stones, neurological symptoms, or other organ damage. Proper identification supports resource allocation for the specialized management these patients require.
Documentation Requirements
- ✓Specific glycine metabolism disorder named in the documentation
- ✓Biochemical or genetic testing confirming the specific diagnosis
- ✓Clinical manifestations and organ involvement documented
- ✓Current treatment plan and monitoring schedule
- ✓Rationale for why the disorder does not fit a more specific code (E72.51 or E72.52)
Commonly Confused Codes
E72.50 — Disorder of glycine metabolism, unspecified: use only when no specific glycine disorder is identifiedE72.51 — Non-ketotic hyperglycinemia: a specific glycine cleavage system defect with its own codeE72.52 — Trimethylaminuria: has its own specific codeE72.89 — Other specified disorders of amino-acid metabolism: broader category for non-glycine amino acid disorders
Code Hierarchy
└E72Other disorders of amino-acid metabolism└E72.5Disorders of glycine metabolism└E72.59Other disorders of glycine metabolism
└E72.59Other disorders of glycine metabolism