E72.50
BillableDisorder of glycine metabolism, unspecified
HCC Category Mapping
V24HCC 23 — Other Significant Endocrine and Metabolic Disorders
0.230ESRDHCC 23 — Other Significant Endocrine and Metabolic Disorders
0.000RxHCCHCC 43 — Other Significant Endocrine and Metabolic Disorders
0.000What This Code Means
A metabolic disorder affecting how the body processes glycine, an amino acid, with the specific type not identified.
Coding Tips
- •This is an unspecified code; use only when the specific glycine metabolism disorder cannot be determined
- •If possible, specify whether this is hyperglycemia, glycine encephalopathy, or another glycine disorder
Clinical Significance
Disorder of glycine metabolism, unspecified, serves as a placeholder when the provider has diagnosed a glycine metabolism disorder but the exact type is not documented. Glycine metabolism disorders can range from benign to severe (such as glycine encephalopathy), making specificity critical. This unspecified code should prompt a query to the provider for additional diagnostic detail.
Documentation Requirements
- ✓Provider statement of a glycine metabolism disorder diagnosis
- ✓Laboratory evidence of abnormal glycine levels (plasma, cerebrospinal fluid, or urine)
- ✓Any available details about the type of glycine disorder
- ✓Clinical manifestations such as seizures, hypotonia, or developmental delay
- ✓Documentation of why more specific diagnosis cannot be determined
Commonly Confused Codes
E72.51 — Non-ketotic hyperglycinemia: specific glycine disorder with distinct pathophysiologyE72.52 — Trimethylaminuria: metabolized differently, involves trimethylamine not glycine directlyE72.59 — Other disorders of glycine metabolism: use when a specific glycine disorder is documented but not NKH or trimethylaminuriaE72.9 — Disorder of amino-acid metabolism, unspecified: even less specific, covering all amino acids
Code Hierarchy
└E72Other disorders of amino-acid metabolism└E72.5Disorders of glycine metabolism└E72.50Disorder of glycine metabolism, unspecified
└E72.50Disorder of glycine metabolism, unspecified