E72.01
BillableCystinuria
HCC Category Mapping
V24HCC 23 — Other Significant Endocrine and Metabolic Disorders
0.230ESRDHCC 23 — Other Significant Endocrine and Metabolic Disorders
0.000RxHCCHCC 42 — Endocrine Disorders and Metabolic Conditions
0.000What This Code Means
An inherited disorder where the body cannot properly reabsorb the amino acid cystine in the kidneys, leading to kidney stones and potential kidney damage.
Coding Tips
- •Document whether the patient has complications such as nephrolithiasis or chronic kidney disease for complete clinical picture
- •Confirm diagnosis through urine amino acid analysis showing elevated cystine levels
Clinical Significance
Cystinuria is the most common inherited cause of kidney stones, resulting from defective renal tubular reabsorption of cystine and dibasic amino acids, causing cystine to crystallize in the urine and form recurrent kidney stones. Without management, recurrent stones can lead to urinary obstruction, infections, and progressive chronic kidney disease. Lifelong management includes high fluid intake, urine alkalinization, and potentially chelation therapy.
Documentation Requirements
- ✓Document urine amino acid analysis confirming cystinuria, stone composition analysis showing cystine, imaging findings of current or prior stones, renal function status, history of stone episodes and surgical interventions, and current management regimen including hydration and alkalinization protocols.