E24.2

Billable

Drug-induced Cushing's syndrome

HCC Category Mapping

V24HCC 23 — Other Significant Endocrine and Metabolic Disorders

0.230

ESRDHCC 23 — Other Significant Endocrine and Metabolic Disorders

0.000

RxHCCHCC 43 — Other Significant Endocrine and Metabolic Disorders

0.000

What This Code Means

Cushing's syndrome caused by taking certain medications (such as corticosteroids) that mimic or trigger the effects of excess cortisol in the body.

Coding Tips

•Always document the specific medication causing the condition in the medical record
•This is iatrogenic Cushing's syndrome; consider coding the medication as an external cause if applicable

Clinical Significance

Drug-induced Cushing syndrome is the most common cause of Cushing syndrome overall, resulting from chronic exogenous corticosteroid use. It produces the full spectrum of cushingoid features including central obesity, moon facies, striae, glucose intolerance, and immunosuppression, with risk of adrenal crisis upon abrupt discontinuation.

Documentation Requirements

✓Document the specific causative medication (prednisone, dexamethasone, inhaled corticosteroids, topical steroids), duration and dose of use, clinical manifestations, cortisol levels, and plan for steroid tapering or management of cushingoid effects.

Use Additional Code

code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)

Commonly Confused Codes

E24.0 (pituitary-dependent Cushing disease from endogenous adrenocorticotropic hormone excess), E24.3 (ectopic adrenocorticotropic hormone syndrome), E24.9 (Cushing syndrome unspecified), E27.3 (drug-induced adrenocortical insufficiency which is the opposite effect).

Code Hierarchy

└E24Cushing's syndrome └E24.2Drug-induced Cushing's syndrome

└E24.2Drug-induced Cushing's syndrome