E22.0
BillableAcromegaly and pituitary gigantism
HCC Category Mapping
V28HCC 51 — Other Significant Endocrine and Metabolic Disorders
0.233V24HCC 23 — Other Significant Endocrine and Metabolic Disorders
0.230ESRDHCC 23 — Other Significant Endocrine and Metabolic Disorders
0.000RxHCCHCC 42 — Endocrine Disorders and Metabolic Conditions
0.000What This Code Means
A condition where the pituitary gland produces excessive growth hormone, causing abnormal growth and enlargement of body tissues and bones in adults (acromegaly) or excessive growth in children (gigantism).
Coding Tips
- •Distinguish between acromegaly (adult-onset) and pituitary gigantism (childhood-onset) as they may have different clinical implications
- •Look for associated complications like diabetes, hypertension, or joint problems that should be coded separately
Clinical Significance
Acromegaly and pituitary gigantism are caused by excess growth hormone production, typically from a pituitary adenoma. Acromegaly in adults causes progressive enlargement of hands, feet, and facial features with significant cardiovascular, metabolic, and joint complications. Pituitary gigantism in children causes excessive linear growth before epiphyseal closure.
Documentation Requirements
- ✓Document the underlying cause (pituitary adenoma size and location), growth hormone and insulin-like growth factor 1 levels, associated complications (diabetes mellitus, cardiomyopathy, sleep apnea, joint disease), treatment status (surgery, medication, radiation), and disease activity.
Excludes 1 — Do NOT code together
Commonly Confused Codes
Code Hierarchy
└E22Hyperfunction of pituitary gland└E22.0Acromegaly and pituitary gigantism
└E22.0Acromegaly and pituitary gigantism