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E09.00 ICD-10-CM Code: Drug or chemical induced diabetes mellitus with hyperosmolarity without nonketotic hyperglycemic-hyperosmolar coma (NKHHC)

E09.00 is not a CMS-HCC payment code. MEAT criteria · RAF Calculator · HCC coding software

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Code lookupE09.00

FY 2026 Apr update / Endocrine, nutritional and metabolic diseases (E00-E89) / Diabetes mellitus (E08-E13)

E09.00

Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidance

Drug or chemical induced diabetes mellitus with hyperosmolarity without nonketotic hyperglycemic-hyperosmolar coma (NKHHC)

This code describes diabetes that develops as a side effect of certain medications or chemical exposure, with very high blood sugar levels and concentrated blood (hyperosmolarity), but without the serious complication of a hyperglycemic crisis. The patient's blood is too concentrated due to high glucose, but they have not developed the life-threatening condition called nonketotic hyperglycemic-hyperosmolar coma.

Buddy the Bee presenting code insight

Buddy Insight

Drug or chemical induced diabetes mellitus with hyperosmolarity without coma represents a serious metabolic derangement where medications or toxic exposures have caused diabetes, and the patient has developed dangerously concentrated blood from extreme hyperglycemia.

CMS-HCC V28

N/A

Not mapped

CMS-HCC V24

Historical

Historical

Not used for CY2026 payment

ACA/HHS

HCC 019

Code-level coefficient reference

ESRD/PACE

HCC 17

Code-level coefficient reference

RXHCC

HCC 30

Code-level coefficient reference

Inclusion Terms

Official

No inclusion terms are included in this display for E09.00. Check the code and parent instructions in the Code Book.

Excludes 2

Official

No Excludes 2 notes are included in this display for E09.00. Check the code and parent instructions in the Code Book.

Includes

Official

No Includes notes are included in this display for E09.00. Check the code and parent instructions in the Code Book.

Excludes 1

Official
  • transitory endocrine and metabolic disorders specific to newborn (P70-P74)Inherited from E00-E89, E09
  • diabetes mellitus due to underlying condition (E08.-)Inherited from E00-E89, E09
  • gestational diabetes (O24.4-)Inherited from E00-E89, E09
  • neonatal diabetes mellitus (P70.2)Inherited from E00-E89, E09
  • postpancreatectomy diabetes mellitus (E13.-)Inherited from E00-E89, E09
  • postprocedural diabetes mellitus (E13.-)Inherited from E00-E89, E09
  • secondary diabetes mellitus NEC (E13.-)Inherited from E00-E89, E09
  • type 1 diabetes mellitus (E10.-)Inherited from E00-E89, E09
  • type 2 diabetes mellitus (E11.-)Inherited from E00-E89, E09

Code First

Official
  • poisoning due to drug or toxin, if applicable (T36-T65 with fifth or sixth character 1-4)Inherited from E09

Use Additional

Official
  • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)Inherited from E09
  • code to identify control using:Inherited from E09
  • injectable non-insulin antidiabetic drugs (Z79.85)Inherited from E09
  • insulin (Z79.4)Inherited from E09
  • oral antidiabetic drugs (Z79.84)Inherited from E09
  • oral hypoglycemic drugs (Z79.84)Inherited from E09

Code Also

Official

No Code Also instructions are included in this display for E09.00. Check the code and parent instructions in the Code Book.

Buddy Documentation Tip

HCC Buddy guidance
The causative drug or chemical must be identified and documented with an additional external cause code from the Table of Drugs and Chemicals.
Serum osmolality, blood glucose levels, and mental status should be recorded.
Documentation must explicitly confirm the absence of nonketotic hyperglycemic-hyperosmolar coma to justify the 'without coma' distinction.

MEAT Support

HCC Buddy guidance
The causative drug or chemical must be identified and documented with an additional external cause code from the Table of Drugs and Chemicals.
Serum osmolality, blood glucose levels, and mental status should be recorded.
Documentation must explicitly confirm the absence of nonketotic hyperglycemic-hyperosmolar coma to justify the 'without coma' distinction.

Audit Caution

HCC Buddy guidance
Failing to identify and code the causative agent is a critical error that may lead to claim denials. Confusing hyperosmolarity with ketoacidosis is another common mistake
they are distinct pathophysiologic states that require different management. Ensure the intent of exposure (adverse effect, poisoning, underdosing) is correctly captured.

Common Mistakes

HCC Buddy guidance
E09.01 (with coma) should be used if the patient loses consciousness.
E09.10 (ketoacidosis without coma) is distinct because the pathophysiology involves acidosis rather than hyperosmolarity.
E11.00 (Type 2 with hyperosmolarity without coma) should not be used when the diabetes is drug-induced.

Current with CMS: FY2026 ICD-10-CM Apr 1 update (effective Apr 1 – Sep 30, 2026) · CMS-HCC V28, 100% phased in for payment year 2026. FY2027 code set already staged for October 1, 2026. How HCC Buddy stays current →

Is E09.00 an HCC code?

E09.00 has no mapping under the current CMS-HCC V28 community payment model. E09.00 has a separate mapping under the CMS-HCC ESRD model (HCC 17 (Diabetes with Acute Complications)) and the Part D RxHCC model (HCC 30 (Diabetes with Complications)); the applicable result needs member context. E09.00 also appears in the HHS-HCC commercial risk model (HCC 019 (HHS-HCC 019 adult, RAF varies by metal level)), which is a commercial market model rather than a Medicare Advantage payment mapping.

Code
E09.00
Description
Drug or chemical induced diabetes mellitus with hyperosmolarity without nonketotic hyperglycemic-hyperosmolar coma (NKHHC)
HCC (V28)
No CMS-HCC V28 mapping
RAF reference coefficient
Billable
Yes
Payment year
2026

HCC Category Mapping

ESRDHCC 17, Diabetes with Acute Complications
Not separately weighted
RxHCCHCC 30, Diabetes with Complications
Not separately weighted

These are source-labeled model coefficients, not member totals. A category may still be removed by hierarchy or model cleanup rules. Weights are not directly comparable across models: CMS-HCC V28 and V24 use Community, Non-Dual, Aged; ESRD uses the dialysis continuing-enrollee model; RxHCC is the Part D continuing-enrollee, non-low-income, aged weight (a larger scale than CMS-HCC). ACA/HHS has no single weight — it varies by metal level. Actual per-patient RAF contribution depends on member context, hierarchy and cleanup rules, interactions, and the model year used by the payer. V28 is the CMS-HCC model phased in over payment years 2024–2026; V24 remains available for historical review.

Work E09.00 in the Code Book — tabular path, V28 RAF reference, and MEAT checklist →

MEAT review for E09.00

For E09.00, confirm that the documentation supports the diagnosis and meets the applicable coding, encounter, program and payer requirements. MEAT (Monitor, Evaluate, Assess, or Treat) is a review mnemonic, not a universal CMS coding rule.

  • MMonitor: signs, symptoms, disease progression, or lab trending documented in the note
  • EEvaluate: test results, medication response, or physical findings reviewed by the provider
  • AAssess: explicit mention in the assessment or plan with acknowledgment of status
  • TTreat: medication, referral, procedure, therapy, or counseling tied to the diagnosis

Coder workflow notes

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What This Code Means

E09.00 is the ICD-10-CM diagnosis code for drug or chemical induced diabetes mellitus with hyperosmolarity without nonketotic hyperglycemic-hyperosmolar coma (nkhhc). This code describes diabetes that develops as a side effect of certain medications or chemical exposure, with very high blood sugar levels and concentrated blood (hyperosmolarity), but without the serious complication of a hyperglycemic crisis. The patient's blood is too concentrated due to high glucose, but they have not developed the life-threatening condition called nonketotic hyperglycemic-hyperosmolar coma. E09.00 sits in the ICD-10-CM chapter for endocrine, nutritional and metabolic diseases (e00-e89), within the section covering diabetes mellitus (e08-e13).

E09.00 has no mapping under the current CMS-HCC V28 community payment model. E09.00 has a separate mapping under the CMS-HCC ESRD model (HCC 17 (Diabetes with Acute Complications)) and the Part D RxHCC model (HCC 30 (Diabetes with Complications)); the applicable result needs member context. E09.00 also appears in the HHS-HCC commercial risk model (HCC 019 (HHS-HCC 019 adult, RAF varies by metal level)), which is a commercial market model rather than a Medicare Advantage payment mapping. Do not assign V28 risk adjustment value from this page; verify the applicable model and payment year before using this code for risk adjustment.

Always identify and document the specific drug or chemical causing the diabetes, as this is required for accurate coding of drug-induced diabetes.

HCC Buddy maintains structured V28 and V24 mapping, source-labeled coefficient references, and MEAT documentation criteria for E09.00 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Coding Tips

  • Always identify and document the specific drug or chemical causing the diabetes, as this is required for accurate coding of drug-induced diabetes
  • Verify that the patient does NOT have NKHHC (nonketotic hyperglycemic-hyperosmolar coma); if they do, use code E09.01 instead

Clinical Significance

Drug or chemical induced diabetes mellitus with hyperosmolarity without coma represents a serious metabolic derangement where medications or toxic exposures have caused diabetes, and the patient has developed dangerously concentrated blood from extreme hyperglycemia. Hyperosmolarity indicates severe dehydration and glucose levels typically exceeding 600 mg/dL. Though the patient has not progressed to coma, this condition requires urgent inpatient management with aggressive fluid resuscitation and insulin therapy.

Documentation Requirements

  • The causative drug or chemical must be identified and documented with an additional external cause code from the Table of Drugs and Chemicals.
  • Serum osmolality, blood glucose levels, and mental status should be recorded.
  • Documentation must explicitly confirm the absence of nonketotic hyperglycemic-hyperosmolar coma to justify the 'without coma' distinction.

Commonly Confused Codes

  • E09.01 (with coma) should be used if the patient loses consciousness.
  • E09.10 (ketoacidosis without coma) is distinct because the pathophysiology involves acidosis rather than hyperosmolarity.
  • E11.00 (Type 2 with hyperosmolarity without coma) should not be used when the diabetes is drug-induced.

Child Codes

Code Hierarchy

Also searched as

  • E09 00
  • E0900

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