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D68.62 ICD-10-CM Code: Lupus anticoagulant syndrome

ICD-10-CM Code View

HCC Buddy Code Card

Digital ICD-10 code-book layout with official code detail, always-visible risk models, Code Trumping, and Buddy coding guidance.

FY 2026 Apr update / Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89) / Coagulation defects, purpura and other hemorrhagic conditions (D65-D69)

D68.62

Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidance

Lupus anticoagulant syndrome

An autoimmune condition where antibodies against phospholipids interfere with blood clotting, paradoxically causing clots despite anticoagulant activity.

Buddy the Bee presenting code insight

Buddy Insight

Lupus anticoagulant syndrome refers to the presence of lupus anticoagulant antibodies that paradoxically prolong in vitro clotting tests (aPTT) while predisposing to in vivo thrombosis.

CMS-HCC V28

0

0

RAF 0

CMS-HCC V24

HCC 48

RAF 0.209

ACA/HHS

0

0

RAF 0

ESRD/PACE

HCC 48

RAF 0.0

RXHCC

0

0

RAF 0

Code Trumping

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Code Book Path

Official
D68Other coagulation defects
D68.6Other thrombophilia
D68.62Lupus anticoagulant syndrome

Inclusion Terms

Official
  • Lupus anticoagulant
  • Presence of systemic lupus erythematosus [SLE] inhibitor

Excludes 2

Official
  • anticardiolipin syndrome (D68.61)
  • antiphospholipid syndrome (D68.61)
  • lupus anticoagulant (LAC) with hemorrhagic disorder (D68.312)

Related Child Codes

Official
D68.61Antiphospholipid syndrome
D68.69Other thrombophilia

Includes

Official

ICD-10-CM does not list Includes notes for D68.62 in this effective period.

Excludes 1

Official
  • lupus anticoagulant (LAC) finding without diagnosis (R76.0)

Code First

Official

ICD-10-CM does not list Code First sequencing instructions for D68.62 in this effective period.

Use Additional

Official

ICD-10-CM does not list Use Additional Code instructions for D68.62 in this effective period.

Code Also

Official

ICD-10-CM does not list Code Also instructions for D68.62 in this effective period.

Buddy Documentation Tip

HCC Buddy guidance
Document positive lupus anticoagulant on two occasions at least 12 weeks apart using validated assays (dilute Russell viper venom time, sensitive aPTT).
Record thrombotic history, association with SLE or other autoimmune conditions, and current anticoagulation management.
Note any confusion with bleeding risk due to prolonged aPTT.

MEAT Support

HCC Buddy guidance
Document positive lupus anticoagulant on two occasions at least 12 weeks apart using validated assays (dilute Russell viper venom time, sensitive aPTT).
Record thrombotic history, association with SLE or other autoimmune conditions, and current anticoagulation management.
Note any confusion with bleeding risk due to prolonged aPTT.

Audit Caution

HCC Buddy guidance
The term 'anticoagulant' is a misnomer — this condition causes thrombosis, not bleeding.
Prolonged aPTT is a lab artifact, not indicative of clinical bleeding risk.
Do not cancel surgeries based solely on lupus anticoagulant-related aPTT prolongation.
Transient positivity during acute illness or infection does not constitute the syndrome — require persistence at 12+ weeks.

Common Mistakes

HCC Buddy guidance
D68.61 (Antiphospholipid syndrome) — broader diagnosis that may include lupus anticoagulant
D68.312 (Antiphospholipid antibody with hemorrhagic disorder) — rare bleeding presentation
M32.x (Systemic lupus erythematosus) — lupus anticoagulant does not require concurrent SLE diagnosis.

Last updated: FY2026 ICD-10-CM Apr update, Apr 1, 2026 through Sep 30, 2026. CMS-HCC V28 is 100% phased in for payment year 2026.

Is D68.62 an HCC code?

Yes. D68.62 maps to Coagulation Defects and Other Specified Hematological Disorders under the V24 model but is not retained in V28.

HCC Category Mapping

V24HCC 48, Coagulation Defects and Other Specified Hematological Disorders
0.209
ESRDHCC 48, Coagulation Defects and Other Specified Hematological Disorders
0.000

RAF weights shown are the community, non-dual, aged base weights from the CMS risk adjustment model file. Actual per-patient RAF contribution depends on member segment, interactions, and the model year used by the payer. V28 is the CMS-HCC model phased in over payment years 2024–2026; V24 remains in use during the transition and for historical data.

MEAT Criteria for D68.62

For D68.62to count as a valid HCC diagnosis in a given encounter, the provider's documentation must show MEAT: Monitor, Evaluate, Assess, or Treat. A diagnosis from a prior year does not carry forward automatically, it has to be re-documented and supported each calendar year.

  • MMonitor: signs, symptoms, disease progression, or lab trending documented in the note
  • EEvaluate: test results, medication response, or physical findings reviewed by the provider
  • AAssess: explicit mention in the assessment or plan with acknowledgment of status
  • TTreat: medication, referral, procedure, therapy, or counseling tied to the diagnosis

Only one of M/E/A/T is required to support the code, but the documentation must be specific enough to show that the provider actually addressed D68.62 during that encounter, not just copy-forwarded from a problem list.

What This Code Means

D68.62 is the ICD-10-CM diagnosis code for lupus anticoagulant syndrome. An autoimmune condition where antibodies against phospholipids interfere with blood clotting, paradoxically causing clots despite anticoagulant activity. D68.62 sits in the ICD-10-CM chapter for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (d50-d89), within the section covering coagulation defects, purpura and other hemorrhagic conditions (d65-d69).

Under the older CMS-HCC V24 model, D68.62 maps to Coagulation Defects and Other Specified Hematological Disorders (HCC 48) with a community, non-dual, aged base RAF weight of 0.209. V28 is the CMS-HCC risk adjustment model that reached 100% phase-in for payment year 2026, replacing V24 which was used during the PY2024–PY2025 transition.

This is a specific type of antiphospholipid syndrome; document positive lupus anticoagulant test results. Because D68.62 maps to a payment HCC, the provider's documentation must satisfy MEAT criteria (Monitor, Evaluate, Assess, or Treat) for the encounter to count toward the patient's Medicare Advantage risk adjustment score. When documentation is ambiguous, coders should issue a provider query rather than assume the highest-specificity variant.

HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for D68.62 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Coding Tips

  • This is a specific type of antiphospholipid syndrome; document positive lupus anticoagulant test results
  • Often associated with recurrent miscarriages and thrombosis; code related complications separately

Clinical Significance

Lupus anticoagulant syndrome refers to the presence of lupus anticoagulant antibodies that paradoxically prolong in vitro clotting tests (aPTT) while predisposing to in vivo thrombosis. Despite its name, it is not exclusive to lupus patients and can occur independently. The prolonged aPTT may cause confusion in perioperative or acute care settings where it could be mistaken for a bleeding risk.

Documentation Requirements

  • Document positive lupus anticoagulant on two occasions at least 12 weeks apart using validated assays (dilute Russell viper venom time, sensitive aPTT).
  • Record thrombotic history, association with SLE or other autoimmune conditions, and current anticoagulation management.
  • Note any confusion with bleeding risk due to prolonged aPTT.

Excludes 1, Do NOT code together

  • lupus anticoagulant (LAC) finding without diagnosis (R76.0)

Excludes 2, Not included here, may code separately

  • anticardiolipin syndrome (D68.61)
  • antiphospholipid syndrome (D68.61)
  • lupus anticoagulant (LAC) with hemorrhagic disorder (D68.312)

Commonly Confused Codes

  • D68.61 (Antiphospholipid syndrome): broader diagnosis that may include lupus anticoagulant
  • D68.312 (Antiphospholipid antibody with hemorrhagic disorder): rare bleeding presentation
  • M32.x (Systemic lupus erythematosus): lupus anticoagulant does not require concurrent SLE diagnosis.

Child Codes

Code Hierarchy

Because D68.62 maps to a payment HCC, the documentation must also satisfy MEAT criteria (Monitor, Evaluate, Assess, or Treat) for the encounter to count toward the patient's risk adjustment score.

Work D68.62 in HCC Buddy

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