What is ICD-10 code D68.00?

D68.00 is the ICD-10-CM diagnosis code for Von Willebrand disease, unspecified. A hereditary bleeding disorder affecting blood clotting and platelet function, but the specific type is not specified or documented. D68.00 is a billable code, meaning it can be reported on a claim as a primary or secondary diagnosis when supported by documentation. D68.00 is part of the FY2026 ICD-10-CM code set published by the CMS National Center for Health Statistics and used on Medicare, Medicaid, and commercial claims in the United States.

Yes. D68.00 is a billable ICD-10-CM code that can be reported on professional and institutional claims as a primary or secondary diagnosis when the provider documentation supports the specific condition described. Billable codes in ICD-10-CM are coded to the highest level of specificity available for the documented diagnosis. D68.00 is current for fiscal year 2026 and remains in the active CMS ICD-10-CM code set published by the National Center for Health Statistics.

Which HCC does D68.00 map to under V28?

D68.00 maps to CMS-HCC V28 HCC 112 (Immune Thrombocytopenia and Specified Coagulation Defects and Hemorrhagic Conditions). The category numbers, labels, and conditions come from the CMS-HCC V28 model file for payment year 2026.

2026 ICD-10-CM D68.00: Von Willebrand disease

D68.00 maps to CMS-HCC V28 112. A source-labeled RAF reference is available. Confirm the documented diagnosis and applicable coding requirements. MEAT criteria · RAF Calculator · free HCC coding tools

ICD-10-CM Code View

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Code lookupD68.00

Effective periodFY2026 Apr Update (Apr 1-Sep 30)

FY 2026 Apr update / Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89) / Coagulation defects, purpura and other hemorrhagic conditions (D65-D69)

D68.00

Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidance

Von Willebrand disease, unspecified

A hereditary bleeding disorder affecting blood clotting and platelet function, but the specific type is not specified or documented.

Buddy Insight

Overview Risk Models Code Book Documentation Audit Notes Edition comparison

CMS-HCC V28

Mapped

HCC 112

Immune Thrombocytopenia and S...

Code-level coefficient reference

CMS-HCC V24

Historical

Not used for standard CY2026 Medicare Advantage payment. Select a historical period to review V24.

Not used for CY2026 payment

ACA/HHS

Mapped

HCC 075

HHS-HCC 075 adult, RAF varies...

Code-level coefficient reference

ESRD/PACE

Mapped

HCC 48

Coagulation Defects and Other...

Code-level coefficient reference

RXHCC

N/A

—

Not risk-adjusted for this model/period.

Not mapped

Code Book Path

Official

D68Other coagulation defects D68.0Von Willebrand disease D68.00Von Willebrand disease, unspecified

Inclusion Terms

Official

No inclusion terms are included in this display for D68.00. Check the code and parent instructions in the Code Book.

Excludes 2

Official

autoimmune disease (systemic) NOS (M35.9)Inherited from D50-D89, D68
certain conditions originating in the perinatal period (P00-P96)Inherited from D50-D89, D68
complications of pregnancy, childbirth and the puerperium (O00-O9A)Inherited from D50-D89, D68
congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)Inherited from D50-D89, D68
endocrine, nutritional and metabolic diseases (E00-E88)Inherited from D50-D89, D68
human immunodeficiency virus [HIV] disease (B20)Inherited from D50-D89, D68
injury, poisoning and certain other consequences of external causes (S00-T88)Inherited from D50-D89, D68
neoplasms (C00-D49)Inherited from D50-D89, D68
symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)Inherited from D50-D89, D68
coagulation defects complicating abortion or ectopic or molar pregnancy (O00-O07, O08.1)Inherited from D50-D89, D68
coagulation defects complicating pregnancy, childbirth and the puerperium (O45.0, O46.0, O67.0, O72.3)Inherited from D50-D89, D68

Related Codes

Official

D68.01Von Willebrand disease, type 1 D68.02Von Willebrand disease, type 2 D68.03Von Willebrand disease, type 3 D68.04Acquired von Willebrand disease D68.09Other von Willebrand disease

Includes

Official

No Includes notes are included in this display for D68.00. Check the code and parent instructions in the Code Book.

Excludes 1

Official

abnormal coagulation profile NOS (R79.1)Inherited from D68, D68.0
capillary fragility (hereditary) (D69.8)Inherited from D68, D68.0
factor VIII deficiency NOS (D66)Inherited from D68, D68.0
factor VIII deficiency with functional defect (D66)Inherited from D68, D68.0

Code First

Official

No Code First sequencing instructions are included in this display for D68.00. Check the code and parent instructions in the Code Book.

Use Additional

Official

No Use Additional Code instructions are included in this display for D68.00. Check the code and parent instructions in the Code Book.

Code Also

Official

No Code Also instructions are included in this display for D68.00. Check the code and parent instructions in the Code Book.

Buddy Documentation Tip

HCC Buddy guidance

Document VWF antigen levels, VWF activity (ristocetin cofactor), factor VIII activity, and multimer analysis results.

Record bleeding history using a standardized bleeding assessment tool, family history of bleeding disorders, and response to desmopressin (DDAVP) challenge.

Specify the type if known to allow more specific coding.

MEAT Support

HCC Buddy guidance

Document VWF antigen levels, VWF activity (ristocetin cofactor), factor VIII activity, and multimer analysis results.

Record bleeding history using a standardized bleeding assessment tool, family history of bleeding disorders, and response to desmopressin (DDAVP) challenge.

Specify the type if known to allow more specific coding.

Audit Caution

HCC Buddy guidance

This unspecified code should only be used when the specific type of von Willebrand disease has not been determined.

Query the provider for type specification when VWF testing has been completed.

Do not assign this code based solely on a prolonged bleeding time without confirmatory VWF testing.

Common Mistakes

HCC Buddy guidance

D69.1 (Qualitative platelet defects) — primary platelet dysfunction rather than VWF deficiency

D66 (Hemophilia A) — both can present with low factor VIII, but the primary defect differs

D68.01-D68.09 (Specified von Willebrand disease types) — more specific codes that should be used when the type is documented.

Current with CMS: FY2026 ICD-10-CM Apr 1 update (effective Apr 1 – Sep 30, 2026) · CMS-HCC V28, 100% phased in for payment year 2026. FY2027 code set already staged for October 1, 2026. How HCC Buddy stays current →

Is D68.00 an HCC code?

Yes. D68.00 (Von Willebrand disease, unspecified) maps to HCC 112, Immune Thrombocytopenia and Specified Coagulation Defects and Hemorrhagic Conditions under the CMS-HCC V28 risk adjustment model, with a source-labeled community non-dual aged reference coefficient of 0.450. Source-labeled code-level coefficients are references, not member totals. Actual contribution depends on complete member context, hierarchy and cleanup rules, interactions, and model year. HCC Buddy's RAF Calculator supports CMS-HCC V28 PY2026 and shows no score unless every required source and calculation check passes. It is billable for payment year 2026.

Coder answer: D68.00 is billable and maps to V28 HCC 112, Immune Thrombocytopenia and Specified Coagulation Defects and Hemorrhagic Conditions. Open it in the Code Book for the tabular path, RAF, and MEAT checklist.

Code: D68.00
Description: Von Willebrand disease, unspecified
HCC (V28): HCC 112 — Immune Thrombocytopenia and Specified Coagulation Defects and Hemorrhagic Conditions
RAF reference coefficient: 0.450
Billable: Yes
Payment year: 2026

HCC Category Mapping

V28HCC 112, Immune Thrombocytopenia and Specified Coagulation Defects and Hemorrhagic Conditions

0.450

ESRDHCC 48, Coagulation Defects and Other Specified Hematological Disorders

Not separately weighted

These are source-labeled model coefficients, not member totals. A category may still be removed by hierarchy or model cleanup rules. Weights are not directly comparable across models: CMS-HCC V28 and V24 use Community, Non-Dual, Aged; ESRD uses the dialysis continuing-enrollee model; RxHCC is the Part D continuing-enrollee, non-low-income, aged weight (a larger scale than CMS-HCC). ACA/HHS has no single weight — it varies by metal level. Actual per-patient RAF contribution depends on member context, hierarchy and cleanup rules, interactions, and the model year used by the payer. V28 is the CMS-HCC model phased in over payment years 2024–2026; V24 remains available for historical review.

Work D68.00 in the Code Book — tabular path, V28 RAF reference, and MEAT checklist →

MEAT review for D68.00

For D68.00, confirm that the documentation supports the diagnosis and meets the applicable coding, encounter, program and payer requirements. MEAT (Monitor, Evaluate, Assess, or Treat) is a review mnemonic, not a universal CMS coding rule.

MMonitor: signs, symptoms, disease progression, or lab trending documented in the note
EEvaluate: test results, medication response, or physical findings reviewed by the provider
AAssess: explicit mention in the assessment or plan with acknowledgment of status
TTreat: medication, referral, procedure, therapy, or counseling tied to the diagnosis

Coder workflow notes

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What This Code Means

D68.00 is the ICD-10-CM diagnosis code for von willebrand disease, unspecified. A hereditary bleeding disorder affecting blood clotting and platelet function, but the specific type is not specified or documented. D68.00 sits in the ICD-10-CM chapter for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (d50-d89), within the section covering coagulation defects, purpura and other hemorrhagic conditions (d65-d69).

Under the CMS-HCC V28 risk adjustment model, D68.00 maps to Immune Thrombocytopenia and Specified Coagulation Defects and Hemorrhagic Conditions (HCC 112) with a source-labeled community, non-dual, aged reference coefficient of 0.450. No V24 mapping is shown for D68.00; use the applicable model and payment year when reviewing the V28 mapping. For CY2026 non-PACE Medicare Advantage, CMS uses 100% of the 2024 CMS-HCC model (V28). PACE uses a separate model blend. Source-labeled code-level coefficients are references, not member totals. Actual contribution depends on complete member context, hierarchy and cleanup rules, interactions, and model year. HCC Buddy's RAF Calculator supports CMS-HCC V28 PY2026 and shows no score unless every required source and calculation check passes.

Request clarification from the provider on the specific type of von Willebrand disease if possible. For D68.00, confirm that the documentation supports the diagnosis and meets the applicable coding, encounter, program and payer requirements. MEAT (Monitor, Evaluate, Assess, or Treat) is a review mnemonic, not a universal CMS coding rule. When documentation is ambiguous, coders should issue a provider query rather than assume the highest-specificity variant.

HCC Buddy maintains structured V28 and V24 mapping, source-labeled coefficient references, and MEAT documentation criteria for D68.00 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Coding Tips

•Request clarification from the provider on the specific type of von Willebrand disease if possible
•If type is documented, use a more specific code (D68.01-D68.09)

Clinical Significance

Von Willebrand disease, unspecified, is the most commonly inherited bleeding disorder, caused by deficiency or dysfunction of von Willebrand factor (VWF), which is essential for platelet adhesion and carries factor VIII. Prevalence is estimated at 1% of the population, though clinically significant disease is much less common. Use of this unspecified code should be avoided when the type is known.

Documentation Requirements

✓Document VWF antigen levels, VWF activity (ristocetin cofactor), factor VIII activity, and multimer analysis results.
✓Record bleeding history using a standardized bleeding assessment tool, family history of bleeding disorders, and response to desmopressin (DDAVP) challenge.
✓Specify the type if known to allow more specific coding.

Commonly Confused Codes

•D69.1 (Qualitative platelet defects): primary platelet dysfunction rather than VWF deficiency
•D66 (Hemophilia A): both can present with low factor VIII, but the primary defect differs
•D68.01-D68.09 (Specified von Willebrand disease types): more specific codes that should be used when the type is documented.