D68.00

Billable

Von Willebrand disease, unspecified

HCC Category Mapping

V28HCC 112 — Von Willebrand Disease and Other Coagulation Defects

0.247

V24HCC 48 — Coagulation Defects and Other Specified Hematological Disorders

0.209

ESRDHCC 48 — Coagulation Defects and Other Specified Hematological Disorders

0.000

What This Code Means

A hereditary bleeding disorder affecting blood clotting and platelet function, but the specific type is not specified or documented.

Coding Tips

•Request clarification from the provider on the specific type of von Willebrand disease if possible
•If type is documented, use a more specific code (D68.01-D68.09)

Clinical Significance

Von Willebrand disease, unspecified, is the most commonly inherited bleeding disorder, caused by deficiency or dysfunction of von Willebrand factor (VWF), which is essential for platelet adhesion and carries factor VIII. Prevalence is estimated at 1% of the population, though clinically significant disease is much less common. Use of this unspecified code should be avoided when the type is known.

Documentation Requirements

✓Document VWF antigen levels, VWF activity (ristocetin cofactor), factor VIII activity, and multimer analysis results.
✓Record bleeding history using a standardized bleeding assessment tool, family history of bleeding disorders, and response to desmopressin (DDAVP) challenge.
✓Specify the type if known to allow more specific coding.

Commonly Confused Codes

D69.1 (Qualitative platelet defects) — primary platelet dysfunction rather than VWF deficiency D66 (Hemophilia A) — both can present with low factor VIII, but the primary defect differs D68.01-D68.09 (Specified von Willebrand disease types) — more specific codes that should be used when the type is documented.

Code Hierarchy

└D68Other coagulation defects └D68.0Von Willebrand disease └D68.00Von Willebrand disease, unspecified

└D68.00Von Willebrand disease, unspecified