D60.1

HCC Category Mapping

What This Code Means

A temporary condition where the bone marrow temporarily stops producing red blood cells, usually resolving on its own within weeks.

Coding Tips

• •Verify documentation confirms the temporary nature and expected resolution of the condition
• •If the condition persists beyond the expected timeframe, consider recoding to D60.0 or D60.9

Clinical Significance

Transient acquired pure red cell aplasia is a temporary cessation of red blood cell production by the bone marrow that typically resolves spontaneously within weeks. The most common cause is parvovirus B19 infection, which directly infects and destroys erythroid precursor cells, producing a transient aplastic crisis especially dangerous in patients with pre-existing hemolytic anemias who depend on compensatory increased red cell production. Other causes include certain medications and acute viral infections that temporarily suppress erythropoiesis.

Documentation Requirements

• ✓Document the temporary nature of the red cell aplasia with expected or actual resolution timeline.
• ✓Record parvovirus B19 serologies (immunoglobulin M for acute infection) or polymerase chain reaction when infection-associated.
• ✓Include hemoglobin values, reticulocyte count showing near-zero production, and normal white blood cell and platelet counts.
• ✓Document any causative agent or triggering event.
• ✓Record transfusion support provided during the aplastic episode and evidence of recovery.

Commonly Confused Codes