D49.8 ICD-10-CM Code: Neoplasm of unspecified behavior of other specified sites
HCC Buddy Code Card
Digital ICD-10 code-book layout with official code detail, always-visible risk models, Code Trumping, and Buddy coding guidance.
FY 2026 Apr update / Neoplasms (C00-D49) / Neoplasms of unspecified behavior (D49)
D49.8
Header CodeICD-10-CMOfficial ICD-10-CMCodebook guidanceNeoplasm of unspecified behavior of other specified sites
Neoplasm of unspecified behavior of other specified sites
CMS-HCC V28
00
RAF 0
CMS-HCC V24
00
RAF 0
ACA/HHS
00
RAF 0
ESRD/PACE
00
RAF 0
RXHCC
00
RAF 0
Code Trumping
Basket needed
Code Book Path
Inclusion Terms
OfficialICD-10-CM does not list inclusion terms for D49.8 in this effective period.
Excludes 2
Official- neoplasms of uncertain behavior (D37-D44, D48)
Related Child Codes
Includes
Official- 'growth' NOS
- neoplasm NOS
- new growth NOS
- tumor NOS
Excludes 1
Official- neoplasm of unspecified behavior of eyelid (skin) (D49.2)
- neoplasm of unspecified behavior of eyelid cartilage (D49.2)
- neoplasm of unspecified behavior of great vessels (D49.2)
- neoplasm of unspecified behavior of optic nerve (D49.7)
Code First
OfficialICD-10-CM does not list Code First sequencing instructions for D49.8 in this effective period.
Use Additional
OfficialICD-10-CM does not list Use Additional Code instructions for D49.8 in this effective period.
Code Also
OfficialICD-10-CM does not list Code Also instructions for D49.8 in this effective period.
Last updated: FY2026 ICD-10-CM Apr update, Apr 1, 2026 through Sep 30, 2026. CMS-HCC V28 is 100% phased in for payment year 2026.
Coder workflow notes
Get the V28 RAF + MEAT cheat sheet
One printable page: confirm a code's V28 HCC status, its RAF weight, and the MEAT your note needs to make it stick. Free, no card.
Free PDF. No card. Unsubscribe anytime.
What This Code Means
D49.8 is the ICD-10-CM diagnosis code for neoplasm of unspecified behavior of other specified sites. D49.8 sits in the ICD-10-CM chapter for neoplasms (c00-d49), within the section covering neoplasms of unspecified behavior (d49).
Header codes like D49.8 cannot be reported on claims directly, they organize child codes that share clinical context but the actual diagnosis must be coded to the highest level of specificity supported by the documentation. Coders should look at D49.8's child codes and select the one that matches the patient's documented presentation, since payers reject header codes submitted as the primary diagnosis. For risk adjustment workflows, header codes never contribute to a Medicare Advantage member's RAF score on their own; only billable child codes that happen to map to a payment HCC affect risk-adjusted plan payments.
HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for D49.8 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.