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D43.3

Billable

Neoplasm of uncertain behavior of cranial nerves

Last updated: FY2026 ICD-10-CM (Oct 1, 2025 – Sep 30, 2026) | CMS-HCC V28 (100% phase-in, PY2026)

Is D43.3 an HCC code?

Yes. D43.3 maps to Melanoma and Other Skin Cancers under the CMS-HCC V28 risk adjustment model (and Breast, Prostate, and Other Cancers and Tumors under V24).

HCC Category Mapping

V28HCC 23Melanoma and Other Skin Cancers
0.251
V24HCC 12Breast, Prostate, and Other Cancers and Tumors
0.150
ESRDHCC 12Breast, Prostate, and Other Cancers and Tumors
0.000
RxHCCHCC 22Cancer, Other Specified Sites
0.000

RAF weights shown are the community, non-dual, aged base weights from the CMS risk adjustment model file. Actual per-patient RAF contribution depends on member segment, interactions, and the model year used by the payer. V28 is the CMS-HCC model phased in over payment years 2024–2026; V24 remains in use during the transition and for historical data.

MEAT Criteria for D43.3

For D43.3 to count as a valid HCC diagnosis in a given encounter, the provider's documentation must show MEAT: Monitor, Evaluate, Assess, or Treat. A diagnosis from a prior year does not carry forward automatically — it has to be re-documented and supported each calendar year.

  • MMonitor: signs, symptoms, disease progression, or lab trending documented in the note
  • EEvaluate: test results, medication response, or physical findings reviewed by the provider
  • AAssess: explicit mention in the assessment or plan with acknowledgment of status
  • TTreat: medication, referral, procedure, therapy, or counseling tied to the diagnosis

Only one of M/E/A/T is required to support the code, but the documentation must be specific enough to show that the provider actually addressed D43.3 during that encounter — not just copy-forwarded from a problem list.

What This Code Means

D43.3 is the ICD-10-CM diagnosis code for neoplasm of uncertain behavior of cranial nerves. A tumor of the cranial nerves (nerves in the head and face) that cannot yet be classified as definitely benign or malignant. D43.3 sits in the ICD-10-CM chapter for neoplasms (c00-d49), within the section covering neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes (d37-d48).

Under the CMS-HCC V28 risk adjustment model, D43.3 maps to Melanoma and Other Skin Cancers (HCC 23) with a community, non-dual, aged base RAF weight of 0.251. Under the older CMS-HCC V24 model, D43.3 maps to Breast, Prostate, and Other Cancers and Tumors (HCC 12) with a community, non-dual, aged base RAF weight of 0.150. V28 is the CMS-HCC risk adjustment model that reached 100% phase-in for payment year 2026, replacing V24 which was used during the PY2024–PY2025 transition.

Specify which cranial nerve is affected if documentation provides this detail. Because D43.3 maps to a payment HCC, the provider's documentation must satisfy MEAT criteria (Monitor, Evaluate, Assess, or Treat) for the encounter to count toward the patient's Medicare Advantage risk adjustment score. When documentation is ambiguous, coders should issue a provider query rather than assume the highest-specificity variant.

HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for D43.3 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Coding Tips

  • Specify which cranial nerve is affected if documentation provides this detail
  • Distinguish from D33.3 (benign neoplasm) and C72.4 (malignant neoplasm) based on pathology findings

Clinical Significance

Neoplasms of uncertain behavior of cranial nerves include tumors such as vestibular schwannomas (acoustic neuromas) and trigeminal nerve tumors that have histological features preventing definitive classification. These tumors can cause significant morbidity through cranial nerve compression, hearing loss, facial weakness, or trigeminal neuralgia.

Documentation Requirements

  • Documentation should specify which cranial nerve is involved when known, supported by magnetic resonance imaging and surgical pathology.
  • The pathology should describe the features leading to uncertain behavior classification.
  • Document any cranial nerve deficits, hearing changes, or other neurological symptoms.

Commonly Confused Codes

  • D33.3 (benign neoplasm of cranial nerves) is used when pathology confirms benign behavior.
  • C72.50 (malignant neoplasm of cranial nerve, unspecified) is used for confirmed malignancies.
  • D42.0 (uncertain behavior of cerebral meninges) involves the meninges rather than the nerves themselves.

Code Hierarchy

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