D43.0

Billable

Neoplasm of uncertain behavior of brain, supratentorial

HCC Category Mapping

V28HCC 23 — Melanoma and Other Skin Cancers

0.251

V24HCC 12 — Breast, Prostate, and Other Cancers and Tumors

0.150

ESRDHCC 12 — Breast, Prostate, and Other Cancers and Tumors

0.000

RxHCCHCC 22 — Cancer, Other Specified Sites

0.000

What This Code Means

A growth in the upper part of the brain (above the tentorium, a membrane dividing brain regions) that cannot yet be classified as definitely cancer or definitely benign.

Coding Tips

•Supratentorial refers to structures above the tentorium cerebelli; ensure this anatomical distinction is documented
•This code is for uncertain behavior lesions; confirmed malignant brain tumors use different C-codes

Clinical Significance

Neoplasms of uncertain behavior in the supratentorial brain involve structures above the tentorium cerebelli, including the cerebral hemispheres, basal ganglia, and thalamus. These tumors often represent low-grade gliomas or atypical tumors that have features preventing clear benign or malignant classification, requiring serial imaging and potential biopsy for definitive diagnosis.

Documentation Requirements

✓Documentation must specify the supratentorial location, supported by neuroimaging (magnetic resonance imaging) showing the tumor above the tentorium cerebelli.
✓Pathology should describe the histological features leading to uncertain behavior classification.
✓Document any neurological deficits, seizure history, or mass effect symptoms.

Excludes 1 — Do NOT code together

neoplasm of uncertain behavior of fourth ventricle (D43.1)

Commonly Confused Codes

D43.1 (infratentorial brain) involves the posterior fossa structures.D33.0 (benign neoplasm, supratentorial brain) is used when pathology confirms benign behavior.C71.0 through C71.4 (malignant neoplasms of cerebrum) are used when malignancy is confirmed.D43.2 (brain, unspecified) should not be used when supratentorial location is documented.

Code Hierarchy

└D43Neoplasm of uncertain behavior of brain and central nervous system └D43.0Neoplasm of uncertain behavior of brain, supratentorial

└D43.0Neoplasm of uncertain behavior of brain, supratentorial