D21.10 ICD-10-CM Code: Benign neoplasm of connective and other soft tissue of unspecified upper limb, including shoulder

D21.10 is the ICD-10-CM diagnosis code for benign neoplasm of connective and other soft tissue of unspecified upper limb, including shoulder. A benign (non-cancerous) tumor of connective tissue or soft tissue in the upper arm or shoulder area when the side is not specified. D21.10 sits in the ICD-10-CM chapter for neoplasms (c00-d49), within the section covering benign neoplasms, except benign neuroendocrine tumors (d10-d36).

D21.10 is a billable ICD-10-CM code but does not map to a payment HCC under the CMS-HCC V28, V24, ESRD, or RxHCC risk adjustment models. It can be reported on Medicare Advantage encounter data submissions but it does not contribute to a beneficiary's RAF score and therefore does not affect risk-adjusted payments to the plan.

Use only when laterality (right vs. left) cannot be determined from documentation.