C93.Z2 maps to CMS-HCC V28 20. A source-labeled RAF reference is available. Confirm the documented diagnosis and applicable coding requirements. MEAT criteria · RAF Calculator · HCC coding software

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Code lookupC93.Z2

Effective periodFY2026 Apr Update (Apr 1-Sep 30)

FY 2026 Apr update / Neoplasms (C00-D49) / Malignant neoplasms of lymphoid, hematopoietic and related tissue (C81-C96)

C93.Z2

Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidance

Other monocytic leukemia, in relapse

A monocytic blood cancer of a type other than the more common varieties, where the cancer has returned after a period of remission.

Buddy Insight

Other monocytic leukemia in relapse represents disease recurrence of a rare monocytic leukemia variant following prior remission.

Overview Risk Models Code Book Documentation Audit Notes Edition comparison

CMS-HCC V28

Mapped

HCC 20

Lung and Other Severe Cancers

Coefficient HCC 20: 1.136 (Community Non-Dual Aged (CNA))

CMS-HCC V24

Historical

Not used for standard CY2026 Medicare Advantage payment. Select a historical period to review V24.

Not used for CY2026 payment

ACA/HHS

Mapped

HCC 009

HHS-HCC 009 adult, RAF varies...

Code-level coefficient reference

ESRD/PACE

Mapped

HCC 9

Lung and Other Severe Cancers

Code-level coefficient reference

RXHCC

Mapped

HCC 19

Leukemias and Other Hematolog...

Code-level coefficient reference

Code Book Path

Official

C93Monocytic leukemia C93.ZOther monocytic leukemia C93.Z2Other monocytic leukemia, in relapse

Inclusion Terms

Official

No inclusion terms are included in this display for C93.Z2. Check the code and parent instructions in the Code Book.

Excludes 2

Official

Kaposi's sarcoma of lymph nodes (C46.3)Inherited from C81-C96
secondary and unspecified neoplasm of lymph nodes (C77.-)Inherited from C81-C96
secondary neoplasm of bone marrow (C79.52)Inherited from C81-C96
secondary neoplasm of spleen (C78.89)Inherited from C81-C96

Related Codes

Official

C93.Z0Other monocytic leukemia, not having achieved remission C93.Z1Other monocytic leukemia, in remission

Includes

Official

monocytoid leukemiaInherited from C93

Excludes 1

Official

personal history of leukemia (Z85.6)Inherited from C93

Code First

Official

No Code First sequencing instructions are included in this display for C93.Z2. Check the code and parent instructions in the Code Book.

Use Additional

Official

No Use Additional Code instructions are included in this display for C93.Z2. Check the code and parent instructions in the Code Book.

Code Also

Official

No Code Also instructions are included in this display for C93.Z2. Check the code and parent instructions in the Code Book.

Buddy Documentation Tip

HCC Buddy guidance

Documentation must confirm prior remission followed by recurrence, with specific evidence of disease return such as rising monocyte counts, reappearance of abnormal cells on blood smear, or bone marrow findings.

The atypical variant characteristics and salvage treatment approach should be documented.

MEAT Support

HCC Buddy guidance

The atypical variant characteristics and salvage treatment approach should be documented.

Audit Caution

HCC Buddy guidance

Only code relapse when prior remission has been clearly documented.

If the rare variant transforms into a more recognizable subtype at relapse, reassign to the appropriate specific code.

Verify that the 'other' designation remains accurate at the time of relapse.

Common Mistakes

HCC Buddy guidance

C93.Z0 (not achieved remission) is for primary treatment failure, not relapse.

C93.92 (unspecified monocytic leukemia, in relapse) lacks the specificity of knowing it is a rare variant.

C93.02 and C93.12 should be used when acute or chronic subtypes are specifically identified.

Current with CMS: FY2026 ICD-10-CM Apr 1 update (effective Apr 1 – Sep 30, 2026) · CMS-HCC V28, 100% phased in for payment year 2026. FY2027 code set already staged for October 1, 2026. How HCC Buddy stays current →

Is C93.Z2 an HCC code?

Yes. C93.Z2 (Other monocytic leukemia, in relapse) maps to HCC 20, Lung and Other Severe Cancers under the CMS-HCC V28 risk adjustment model, with a source-labeled community non-dual aged reference coefficient of 1.136. Source-labeled code-level coefficients are references, not member totals. Actual contribution depends on complete member context, hierarchy and cleanup rules, interactions, and model year. HCC Buddy's RAF Calculator supports CMS-HCC V28 PY2026 and shows no score unless every required source and calculation check passes. It is billable for payment year 2026.

Coder answer: C93.Z2 is billable and maps to V28 HCC 20, Lung and Other Severe Cancers. Open it in the Code Book for the tabular path, RAF, and MEAT checklist.

Code: C93.Z2
Description: Other monocytic leukemia, in relapse
HCC (V28): HCC 20 — Lung and Other Severe Cancers
RAF reference coefficient: 1.136
Billable: Yes
Payment year: 2026

HCC Category Mapping

V28HCC 20, Lung and Other Severe Cancers

1.136

ESRDHCC 9, Lung and Other Severe Cancers

Not separately weighted

RxHCCHCC 19, Leukemias and Other Hematologic Cancers

Not separately weighted

These are source-labeled model coefficients, not member totals. A category may still be removed by hierarchy or model cleanup rules. Weights are not directly comparable across models: CMS-HCC V28 and V24 use Community, Non-Dual, Aged; ESRD uses the dialysis continuing-enrollee model; RxHCC is the Part D continuing-enrollee, non-low-income, aged weight (a larger scale than CMS-HCC). ACA/HHS has no single weight — it varies by metal level. Actual per-patient RAF contribution depends on member context, hierarchy and cleanup rules, interactions, and the model year used by the payer. V28 is the CMS-HCC model phased in over payment years 2024–2026; V24 remains available for historical review.

Work C93.Z2 in the Code Book — tabular path, V28 RAF reference, and MEAT checklist →

MEAT review for C93.Z2

For C93.Z2, confirm that the documentation supports the diagnosis and meets the applicable coding, encounter, program and payer requirements. MEAT (Monitor, Evaluate, Assess, or Treat) is a review mnemonic, not a universal CMS coding rule.

MMonitor: signs, symptoms, disease progression, or lab trending documented in the note
EEvaluate: test results, medication response, or physical findings reviewed by the provider
AAssess: explicit mention in the assessment or plan with acknowledgment of status
TTreat: medication, referral, procedure, therapy, or counseling tied to the diagnosis

Coder workflow notes

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What This Code Means

C93.Z2 is the ICD-10-CM diagnosis code for other monocytic leukemia, in relapse. A monocytic blood cancer of a type other than the more common varieties, where the cancer has returned after a period of remission. C93.Z2 sits in the ICD-10-CM chapter for neoplasms (c00-d49), within the section covering malignant neoplasms of lymphoid, hematopoietic and related tissue (c81-c96).

Under the CMS-HCC V28 risk adjustment model, C93.Z2 maps to Lung and Other Severe Cancers (HCC 20) with a source-labeled community, non-dual, aged reference coefficient of 1.136. For CY2026 non-PACE Medicare Advantage, CMS uses 100% of the 2024 CMS-HCC model (V28). PACE uses a separate model blend. Source-labeled code-level coefficients are references, not member totals. Actual contribution depends on complete member context, hierarchy and cleanup rules, interactions, and model year. HCC Buddy's RAF Calculator supports CMS-HCC V28 PY2026 and shows no score unless every required source and calculation check passes.

The 'Z' indicates other specified monocytic leukemia; document the specific subtype if available. For C93.Z2, confirm that the documentation supports the diagnosis and meets the applicable coding, encounter, program and payer requirements. MEAT (Monitor, Evaluate, Assess, or Treat) is a review mnemonic, not a universal CMS coding rule. When documentation is ambiguous, coders should issue a provider query rather than assume the highest-specificity variant.

HCC Buddy maintains structured V28 and V24 mapping, source-labeled coefficient references, and MEAT documentation criteria for C93.Z2 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Coding Tips

•The 'Z' indicates other specified monocytic leukemia; document the specific subtype if available
•Verify that prior remission is documented before coding relapse

Clinical Significance

Other monocytic leukemia in relapse represents disease recurrence of a rare monocytic leukemia variant following prior remission. These relapsed atypical subtypes pose particular management challenges due to limited salvage therapy evidence and often require individualized treatment approaches.

Documentation Requirements

✓Documentation must confirm prior remission followed by recurrence, with specific evidence of disease return such as rising monocyte counts, reappearance of abnormal cells on blood smear, or bone marrow findings.
✓The atypical variant characteristics and salvage treatment approach should be documented.

Commonly Confused Codes

•C93.Z0 (not achieved remission) is for primary treatment failure, not relapse.
•C93.92 (unspecified monocytic leukemia, in relapse) lacks the specificity of knowing it is a rare variant.
•C93.02 and C93.12 should be used when acute or chronic subtypes are specifically identified.