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C92.6 ICD-10-CM Code: Acute myeloid leukemia with 11q23-abnormality

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FY 2026 Apr update / Neoplasms (C00-D49) / Malignant neoplasms of lymphoid, hematopoietic and related tissue (C81-C96)

C92.6

Header CodeICD-10-CMOfficial ICD-10-CMCodebook guidance

Acute myeloid leukemia with 11q23-abnormality

Acute myeloid leukemia with 11q23-abnormality

CMS-HCC V28

0

0

RAF 0

CMS-HCC V24

0

0

RAF 0

ACA/HHS

0

0

RAF 0

ESRD/PACE

0

0

RAF 0

RXHCC

0

0

RAF 0

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Code Book Path

Official
C92Myeloid leukemia
C92.6Acute myeloid leukemia with 11q23-abnormality

Inclusion Terms

Official
  • Acute myeloid leukemia with variation of MLL-gene

Excludes 2

Official

ICD-10-CM does not list Excludes 2 notes for C92.6 in this effective period.

Related Child Codes

Official
C92.60Acute myeloid leukemia with 11q23-abnormality not having achieved remission
C92.61Acute myeloid leukemia with 11q23-abnormality in remission
C92.62Acute myeloid leukemia with 11q23-abnormality in relapse

Includes

Official
  • granulocytic leukemia
  • myelogenous leukemia

Excludes 1

Official
  • personal history of leukemia (Z85.6)

Code First

Official

ICD-10-CM does not list Code First sequencing instructions for C92.6 in this effective period.

Use Additional

Official

ICD-10-CM does not list Use Additional Code instructions for C92.6 in this effective period.

Code Also

Official
  • , if applicable, pancytopenia (acquired) (D61.818)

Last updated: FY2026 ICD-10-CM Apr update, Apr 1, 2026 through Sep 30, 2026. CMS-HCC V28 is 100% phased in for payment year 2026.

What This Code Means

C92.6 is the ICD-10-CM diagnosis code for acute myeloid leukemia with 11q23-abnormality. C92.6 sits in the ICD-10-CM chapter for neoplasms (c00-d49), within the section covering malignant neoplasms of lymphoid, hematopoietic and related tissue (c81-c96).

Header codes like C92.6 cannot be reported on claims directly, they organize child codes that share clinical context but the actual diagnosis must be coded to the highest level of specificity supported by the documentation. Coders should look at C92.6's child codes and select the one that matches the patient's documented presentation, since payers reject header codes submitted as the primary diagnosis. For risk adjustment workflows, header codes never contribute to a Medicare Advantage member's RAF score on their own; only billable child codes that happen to map to a payment HCC affect risk-adjusted plan payments.

HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for C92.6 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Child Codes

Code Hierarchy

C92Myeloid leukemiaC92.6Acute myeloid leukemia with 11q23-abnormality
C92.6Acute myeloid leukemia with 11q23-abnormality

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