C84.18
BillableSézary disease, lymph nodes of multiple sites
HCC Category Mapping
V28HCC 17 — Metastatic Cancer and Acute Leukemia
0.368V24HCC 10 — Lymphoma and Other Cancers
0.675ESRDHCC 10 — Lymphoma and Other Cancers
0.000RxHCCHCC 19 — Lymphoma and Other Cancers
0.000What This Code Means
Sézary disease is a rare type of blood cancer that affects T-cells (a type of white blood cell) and causes skin problems, itching, and enlarged lymph nodes in multiple areas of the body. This code specifically indicates the disease has spread to lymph nodes in more than one location.
Coding Tips
- •Verify documentation specifies involvement of multiple lymph node sites; if only one site is involved, use C84.10 instead
- •Sézary disease is a cutaneous T-cell lymphoma; ensure the diagnosis is clearly documented as Sézary disease and not other similar conditions like mycosis fungoides
Clinical Significance
Sezary disease involving lymph nodes at multiple sites indicates widespread nodal disease in this aggressive leukemic T-cell lymphoma. Multi-site lymphadenopathy is common in Sezary disease given its systemic nature with circulating malignant T-cells. This code captures the extent of nodal involvement which impacts staging and treatment decisions.
Documentation Requirements
- ✓Peripheral blood demonstrating circulating Sezary cells
- ✓Imaging documenting lymph node involvement at two or more distinct regions
- ✓Skin biopsy confirming cutaneous T-cell lymphoma
- ✓TNMB staging reflecting widespread nodal disease
- ✓Systemic treatment plan
Commonly Confused Codes
Code Hierarchy
└C84Mature T/NK-cell lymphomas└C84.1Sézary disease└C84.18Sézary disease, lymph nodes of multiple sites
└C84.18Sézary disease, lymph nodes of multiple sites