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C43.52 ICD-10-CM Code: Malignant melanoma of skin of breast

C43.52 maps to CMS-HCC V28 23 (RAF 0.186). Documentation must support MEAT. MEAT criteria · RAF calculator · HCC coding software

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FY 2026 Apr update / Neoplasms (C00-D49) / Melanoma and other malignant neoplasms of skin (C43-C44)

C43.52

Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidance

Malignant melanoma of skin of breast

A type of skin cancer (melanoma) that develops on the skin of the breast area. This aggressive cancer requires immediate medical attention and treatment.

Buddy the Bee presenting code insight

Buddy Insight

Malignant melanoma of the skin of the breast.

CMS-HCC V28

HCC 23

RAF 0.186

CMS-HCC V24

HCC 12

RAF 0.150

ACA/HHS

HCC 13

Varies by metal level

ESRD/PACE

HCC 12

RAF 0.045

RXHCC

HCC 22

RAF 0.124

Code Book Path

Official
C43Malignant melanoma of skin
C43.5Malignant melanoma of trunk
C43.52Malignant melanoma of skin of breast

Inclusion Terms

Official

ICD-10-CM does not list inclusion terms for C43.52 in this effective period.

Excludes 2

Official
  • malignant neoplasm of anus NOS (C21.0)
  • malignant neoplasm of scrotum (C63.2)

Related Child Codes

Official
C43.51Malignant melanoma of anal skin
C43.59Malignant melanoma of other part of trunk

Includes

Official

ICD-10-CM does not list Includes notes for C43.52 in this effective period.

Excludes 1

Official

ICD-10-CM does not list Excludes 1 notes for C43.52 in this effective period.

Code First

Official

ICD-10-CM does not list Code First sequencing instructions for C43.52 in this effective period.

Use Additional

Official

ICD-10-CM does not list Use Additional Code instructions for C43.52 in this effective period.

Code Also

Official

ICD-10-CM does not list Code Also instructions for C43.52 in this effective period.

Buddy Documentation Tip

HCC Buddy guidance
Confirmation the melanoma arises from the breast SKIN, not breast parenchyma
Laterality (right vs. left breast skin) if documented
Breslow depth and ulceration status
Sentinel lymph node biopsy results (axillary nodes for breast skin)

MEAT Support

HCC Buddy guidance
Confirmation the melanoma arises from the breast SKIN, not breast parenchyma
Laterality (right vs. left breast skin) if documented
Breslow depth and ulceration status
Sentinel lymph node biopsy results (axillary nodes for breast skin)

Audit Caution

HCC Buddy guidance
Confusing breast skin melanoma with breast cancer (C50.x) — these are completely different diseases with different treatments and prognoses
Staging breast skin melanoma using breast cancer staging instead of melanoma AJCC staging
Not specifying that the melanoma is cutaneous — pathology confirmation of melanocytic origin is essential
Failing to evaluate axillary sentinel nodes which are the primary drainage basin for breast skin

Common Mistakes

HCC Buddy guidance
C50.x — Malignant neoplasm of breast; for ductal, lobular, and other breast PARENCHYMAL cancers — completely different disease
C43.59 — Melanoma of other part of trunk; if the melanoma is on adjacent chest wall skin rather than the breast skin specifically
C43.51 — Melanoma of anal skin; different trunk site
C44.521 — Squamous cell carcinoma of skin of breast; different histology, same site

Current with CMS: FY2026 ICD-10-CM Apr 1 update (effective Apr 1 – Sep 30, 2026) · CMS-HCC V28, 100% phased in for payment year 2026. FY2027 code set already staged for October 1, 2026. How HCC Buddy stays current →

Is C43.52 an HCC code?

Yes. C43.52 (Malignant melanoma of skin of breast) maps to Prostate, Breast, and Other Cancers and Tumors under the CMS-HCC V28 risk adjustment model (and Breast, Prostate, and Other Cancers and Tumors under V24), with a community non-dual aged RAF of 0.186. It is billable for payment year 2026.

Coder answer: C43.52 is billable and maps to V28 HCC 23, Prostate, Breast, and Other Cancers and Tumors. Open it in the Code Book for the tabular path, RAF, and MEAT checklist.

Code
C43.52
Description
Malignant melanoma of skin of breast
HCC (V28)
HCC 23 — Prostate, Breast, and Other Cancers and Tumors
RAF
0.186
Billable
Yes
Payment year
2026

HCC Category Mapping

V28HCC 23, Prostate, Breast, and Other Cancers and Tumors
0.186
V24HCC 12, Breast, Prostate, and Other Cancers and Tumors
0.150
ESRDHCC 12, Breast, Prostate, and Other Cancers and Tumors
0.045
RxHCCHCC 22, Cancer, Other Specified Sites
0.124

Each model's RAF is its CMS base weight for that model's standard population, so weights are not directly comparable across models: CMS-HCC V28 and V24 use Community, Non-Dual, Aged; ESRD uses the dialysis continuing-enrollee model; RxHCC is the Part D continuing-enrollee, non-low-income, aged weight (a larger scale than CMS-HCC). ACA/HHS has no single weight — it varies by metal level. Actual per-patient RAF contribution depends on member segment, interactions, and the model year used by the payer. V28 is the CMS-HCC model phased in over payment years 2024–2026; V24 remains in use during the transition and for historical data.

Work C43.52 in the Code Book — tabular path, V28 RAF, and MEAT checklist →

MEAT Criteria for C43.52

For C43.52 to count as a valid HCC diagnosis in a given encounter, the provider's documentation must show MEAT: Monitor, Evaluate, Assess, or Treat. A diagnosis from a prior year does not carry forward automatically, it has to be re-documented and supported each calendar year.

  • MMonitor: signs, symptoms, disease progression, or lab trending documented in the note
  • EEvaluate: test results, medication response, or physical findings reviewed by the provider
  • AAssess: explicit mention in the assessment or plan with acknowledgment of status
  • TTreat: medication, referral, procedure, therapy, or counseling tied to the diagnosis

Only one of M/E/A/T is required to support the code, but the documentation must be specific enough to show that the provider actually addressed C43.52 during that encounter, not just copy-forwarded from a problem list.

Coder workflow notes

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What This Code Means

C43.52 is the ICD-10-CM diagnosis code for malignant melanoma of skin of breast. A type of skin cancer (melanoma) that develops on the skin of the breast area. This aggressive cancer requires immediate medical attention and treatment. C43.52 sits in the ICD-10-CM chapter for neoplasms (c00-d49), within the section covering melanoma and other malignant neoplasms of skin (c43-c44).

Under the CMS-HCC V28 risk adjustment model, C43.52 maps to Prostate, Breast, and Other Cancers and Tumors (HCC 23) with a community, non-dual, aged base RAF weight of 0.186. Under the older CMS-HCC V24 model, C43.52 maps to Breast, Prostate, and Other Cancers and Tumors (HCC 12) with a community, non-dual, aged base RAF weight of 0.150. V28 is the CMS-HCC risk adjustment model that reached 100% phase-in for payment year 2026, replacing V24 which was used during the PY2024–PY2025 transition.

Confirm documentation specifies skin of breast rather than breast tissue itself. Because C43.52 maps to a payment HCC, the provider's documentation must satisfy MEAT criteria (Monitor, Evaluate, Assess, or Treat) for the encounter to count toward the patient's Medicare Advantage risk adjustment score. When documentation is ambiguous, coders should issue a provider query rather than assume the highest-specificity variant.

HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for C43.52 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Coding Tips

  • Confirm documentation specifies skin of breast rather than breast tissue itself
  • Consider laterality (right vs. left breast) if documented, though this code does not differentiate

Clinical Significance

Malignant melanoma of the skin of the breast. This refers to melanoma arising from the cutaneous surface of the breast, not breast carcinoma. Breast skin melanoma follows the same principles as other cutaneous melanomas and should not be confused with ductal or lobular breast cancer. It is more common in sun-exposed upper chest areas.

Documentation Requirements

  • Confirmation the melanoma arises from the breast SKIN, not breast parenchyma
  • Laterality (right vs. left breast skin) if documented
  • Breslow depth and ulceration status
  • Sentinel lymph node biopsy results (axillary nodes for breast skin)
  • AJCC melanoma staging (NOT breast cancer staging)
  • Treatment plan (wide excision, sentinel lymph node biopsy)

Commonly Confused Codes

  • C50.x: Malignant neoplasm of breast; for ductal, lobular, and other breast PARENCHYMAL cancers: completely different disease
  • C43.59: Melanoma of other part of trunk; if the melanoma is on adjacent chest wall skin rather than the breast skin specifically
  • C43.51: Melanoma of anal skin; different trunk site
  • C44.521: Squamous cell carcinoma of skin of breast; different histology, same site

Child Codes

Code Hierarchy

Because C43.52 maps to a payment HCC, the documentation must also satisfy MEAT criteria (Monitor, Evaluate, Assess, or Treat) for the encounter to count toward the patient's risk adjustment score.

C43.52 maps to CMS-HCC V28 category 23, Prostate, Breast, and Other Cancers and Tumors. See the ICD-10 to HCC mapping hub for how the V28 crosswalk works. Because C43.52 carries a payment HCC, you can see what it adds to a RAF score and check the documentation the chart needs before it is submitted.

Work C43.52 in HCC Buddy

Open C43.52 in the Code Book for the full Index-to-Tabular path, MEAT checklist, and V28 HCC mapping, or in the Encoder to code from a keyword search. Pro includes 7 days to try everything, no card required.