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A52.05 ICD-10-CM Code: Other cerebrovascular syphilis

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FY 2026 Apr update / Certain infectious and parasitic diseases (A00-B99) / Infections with a predominantly sexual mode of transmission (A50-A64)

A52.05

Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidance

Other cerebrovascular syphilis

This code describes syphilis that affects blood vessels in the brain, causing complications like stroke or other neurological problems, excluding the specific condition of general paresis of the insane. This is a late-stage manifestation of untreated syphilis affecting the central nervous system.

CMS-HCC V28

0

0

RAF 0

CMS-HCC V24

0

0

RAF 0

ACA/HHS

0

0

RAF 0

ESRD/PACE

0

0

RAF 0

RXHCC

0

0

RAF 0

Code Trumping

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Code Book Path

Official
A52Late syphilis
A52.0Cardiovascular and cerebrovascular syphilis
A52.05Other cerebrovascular syphilis

Inclusion Terms

Official
  • Syphilitic cerebral aneurysm (ruptured) (non-ruptured)
  • Syphilitic cerebral thrombosis

Excludes 2

Official

ICD-10-CM does not list Excludes 2 notes for A52.05 in this effective period.

Related Child Codes

Official
A52.00Cardiovascular syphilis, unspecified
A52.01Syphilitic aneurysm of aorta
A52.02Syphilitic aortitis
A52.03Syphilitic endocarditis
A52.04Syphilitic cerebral arteritis

Includes

Official

ICD-10-CM does not list Includes notes for A52.05 in this effective period.

Excludes 1

Official

ICD-10-CM does not list Excludes 1 notes for A52.05 in this effective period.

Code First

Official

ICD-10-CM does not list Code First sequencing instructions for A52.05 in this effective period.

Use Additional

Official

ICD-10-CM does not list Use Additional Code instructions for A52.05 in this effective period.

Code Also

Official

ICD-10-CM does not list Code Also instructions for A52.05 in this effective period.

Buddy Documentation Tip

HCC Buddy guidance
Verify documentation specifies neurosyphilis with cerebrovascular involvement but is NOT general paresis of the insane (GPI), as A52.04 is the specific code for GPI
Ensure the patient has confirmed syphilis diagnosis and documented evidence of cerebrovascular complications such as stroke, aneurysm, or arteritis related to syphilis

Last updated: FY2026 ICD-10-CM Apr update, Apr 1, 2026 through Sep 30, 2026. CMS-HCC V28 is 100% phased in for payment year 2026.

Is A52.05 an HCC code?

No. A52.05 is a billable ICD-10-CM code but does not map to any HCC category in V28, V24, ESRD, or RxHCC.

This code does not map to an HCC category in any model (V28, V24, ESRD, RxHCC).

What This Code Means

A52.05 is the ICD-10-CM diagnosis code for other cerebrovascular syphilis. This code describes syphilis that affects blood vessels in the brain, causing complications like stroke or other neurological problems, excluding the specific condition of general paresis of the insane. This is a late-stage manifestation of untreated syphilis affecting the central nervous system. A52.05 sits in the ICD-10-CM chapter for certain infectious and parasitic diseases (a00-b99), within the section covering infections with a predominantly sexual mode of transmission (a50-a64).

A52.05 is a billable ICD-10-CM code but does not map to a payment HCC under the CMS-HCC V28, V24, ESRD, or RxHCC risk adjustment models. It can be reported on Medicare Advantage encounter data submissions but it does not contribute to a beneficiary's RAF score and therefore does not affect risk-adjusted payments to the plan.

Verify documentation specifies neurosyphilis with cerebrovascular involvement but is NOT general paresis of the insane (GPI), as A52.04 is the specific code for GPI.

HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for A52.05 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Coding Tips

  • Verify documentation specifies neurosyphilis with cerebrovascular involvement but is NOT general paresis of the insane (GPI), as A52.04 is the specific code for GPI
  • Ensure the patient has confirmed syphilis diagnosis and documented evidence of cerebrovascular complications such as stroke, aneurysm, or arteritis related to syphilis

Child Codes

Code Hierarchy

Work A52.05 in HCC Buddy

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