A49.3 ICD-10-CM Code: Mycoplasma infection, unspecified site
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FY 2026 Apr update / Certain infectious and parasitic diseases (A00-B99) / Other bacterial diseases (A30-A49)
A49.3
Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidanceMycoplasma infection, unspecified site
A bacterial infection caused by Mycoplasma organisms that has been identified but the specific location in the body where the infection is occurring is not documented. Mycoplasma bacteria typically cause respiratory infections or urinary tract infections.
CMS-HCC V28
00
RAF 0
CMS-HCC V24
00
RAF 0
ACA/HHS
00
RAF 0
ESRD/PACE
00
RAF 0
RXHCC
00
RAF 0
Code Trumping
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Code Book Path
Inclusion Terms
OfficialICD-10-CM does not list inclusion terms for A49.3 in this effective period.
Excludes 2
OfficialICD-10-CM does not list Excludes 2 notes for A49.3 in this effective period.
Related Child Codes
Includes
OfficialICD-10-CM does not list Includes notes for A49.3 in this effective period.
Excludes 1
Official- bacterial agents as the cause of diseases classified elsewhere (B95-B96)
- chlamydial infection NOS (A74.9)
- meningococcal infection NOS (A39.9)
- rickettsial infection NOS (A79.9)
- spirochetal infection NOS (A69.9)
Code First
OfficialICD-10-CM does not list Code First sequencing instructions for A49.3 in this effective period.
Use Additional
OfficialICD-10-CM does not list Use Additional Code instructions for A49.3 in this effective period.
Code Also
OfficialICD-10-CM does not list Code Also instructions for A49.3 in this effective period.
Buddy Documentation Tip
Last updated: FY2026 ICD-10-CM Apr update, Apr 1, 2026 through Sep 30, 2026. CMS-HCC V28 is 100% phased in for payment year 2026.
Is A49.3 an HCC code?
No. A49.3 is a billable ICD-10-CM code but does not map to any HCC category in V28, V24, ESRD, or RxHCC.
Coder workflow notes
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This code does not map to an HCC category in any model (V28, V24, ESRD, RxHCC).
What This Code Means
A49.3 is the ICD-10-CM diagnosis code for mycoplasma infection, unspecified site. A bacterial infection caused by Mycoplasma organisms that has been identified but the specific location in the body where the infection is occurring is not documented. Mycoplasma bacteria typically cause respiratory infections or urinary tract infections. A49.3 sits in the ICD-10-CM chapter for certain infectious and parasitic diseases (a00-b99), within the section covering other bacterial diseases (a30-a49).
A49.3 is a billable ICD-10-CM code but does not map to a payment HCC under the CMS-HCC V28, V24, ESRD, or RxHCC risk adjustment models. It can be reported on Medicare Advantage encounter data submissions but it does not contribute to a beneficiary's RAF score and therefore does not affect risk-adjusted payments to the plan.
Use this code only when the site of infection is truly unspecified; if documentation indicates a specific site (such as respiratory tract or urinary tract), use the more specific Mycoplasma code for that location.
HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for A49.3 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.
Coding Tips
- •Use this code only when the site of infection is truly unspecified; if documentation indicates a specific site (such as respiratory tract or urinary tract), use the more specific Mycoplasma code for that location
- •Query the provider if the infection site can be determined from clinical findings, test results, or treatment documentation, as specificity improves clinical clarity and may affect reimbursement