Skip to content

A49.01

Billable

Methicillin susceptible Staphylococcus aureus infection, unspecified site

Last updated: FY2026 ICD-10-CM (Oct 1, 2025 – Sep 30, 2026) | CMS-HCC V28 (100% phase-in, PY2026)

Is A49.01 an HCC code?

No. A49.01 is a billable ICD-10-CM code but does not map to any HCC category in V28, V24, ESRD, or RxHCC.

This code does not map to an HCC category in any model (V28, V24, ESRD, RxHCC).

What This Code Means

A49.01 is the ICD-10-CM diagnosis code for methicillin susceptible staphylococcus aureus infection, unspecified site. This code describes a bacterial infection caused by Staphylococcus aureus (a common bacteria) that responds to methicillin antibiotics, but the specific location of the infection in the body is not documented. It's used when a staph infection is confirmed but the exact site hasn't been specified in the medical record. A49.01 sits in the ICD-10-CM chapter for certain infectious and parasitic diseases (a00-b99), within the section covering other bacterial diseases (a30-a49).

A49.01 is a billable ICD-10-CM code but does not map to a payment HCC under the CMS-HCC V28, V24, ESRD, or RxHCC risk adjustment models. It can be reported on Medicare Advantage encounter data submissions but it does not contribute to a beneficiary's RAF score and therefore does not affect risk-adjusted payments to the plan.

Query the provider if a more specific infection site can be identified (such as skin, bone, bloodstream, or respiratory), as this would allow for a more precise code that may affect treatment and reimbursement.

HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for A49.01 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Coding Tips

  • Query the provider if a more specific infection site can be identified (such as skin, bone, bloodstream, or respiratory), as this would allow for a more precise code that may affect treatment and reimbursement
  • Ensure documentation clearly distinguishes between methicillin-susceptible (A49.01) and methicillin-resistant (MRSA, A49.02) strains, as antibiotic resistance significantly impacts clinical management and coding accuracy

Code Hierarchy

Open A49.01 in the Interactive Encoder

See full code details, AI coding tips, HCC mappings, and related codes in our interactive encoder. Start your 14-day Pro trial — no credit card required.