A06.6 ICD-10-CM Code: Amebic brain abscess
HCC Buddy Code Card
Digital ICD-10 code-book layout with official code detail, always-visible risk models, Code Trumping, and Buddy coding guidance.
FY 2026 Apr update / Certain infectious and parasitic diseases (A00-B99) / Intestinal infectious diseases (A00-A09)
A06.6
Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidanceAmebic brain abscess
A brain infection caused by a parasitic amoeba that forms a pus-filled cavity in the brain tissue. This is a serious condition that occurs when the parasite spreads from the intestines or liver to the brain.
CMS-HCC V28
00
RAF 0
CMS-HCC V24
00
RAF 0
ACA/HHS
00
RAF 0
ESRD/PACE
00
RAF 0
RXHCC
00
RAF 0
Code Trumping
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Code Book Path
Inclusion Terms
Official- Amebic abscess of brain (and liver) (and lung)
Excludes 2
Official- acanthamebiasis (B60.1-)
- Naegleriasis (B60.2)
Related Child Codes
Includes
Official- infection due to Entamoeba histolytica
Excludes 1
Official- other protozoal intestinal diseases (A07.-)
Code First
OfficialICD-10-CM does not list Code First sequencing instructions for A06.6 in this effective period.
Use Additional
OfficialICD-10-CM does not list Use Additional Code instructions for A06.6 in this effective period.
Code Also
OfficialICD-10-CM does not list Code Also instructions for A06.6 in this effective period.
Buddy Documentation Tip
Last updated: FY2026 ICD-10-CM Apr update, Apr 1, 2026 through Sep 30, 2026. CMS-HCC V28 is 100% phased in for payment year 2026.
Is A06.6 an HCC code?
No. A06.6 is a billable ICD-10-CM code but does not map to any HCC category in V28, V24, ESRD, or RxHCC.
This code does not map to an HCC category in any model (V28, V24, ESRD, RxHCC).
What This Code Means
A06.6 is the ICD-10-CM diagnosis code for amebic brain abscess. A brain infection caused by a parasitic amoeba that forms a pus-filled cavity in the brain tissue. This is a serious condition that occurs when the parasite spreads from the intestines or liver to the brain. A06.6 sits in the ICD-10-CM chapter for certain infectious and parasitic diseases (a00-b99), within the section covering intestinal infectious diseases (a00-a09).
A06.6 is a billable ICD-10-CM code but does not map to a payment HCC under the CMS-HCC V28, V24, ESRD, or RxHCC risk adjustment models. It can be reported on Medicare Advantage encounter data submissions but it does not contribute to a beneficiary's RAF score and therefore does not affect risk-adjusted payments to the plan.
Verify documentation confirms amebic etiology (caused by Entamoeba histolytica) rather than other types of brain abscess, as this distinction is critical for accurate coding.
HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for A06.6 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.
Coding Tips
- •Verify documentation confirms amebic etiology (caused by Entamoeba histolytica) rather than other types of brain abscess, as this distinction is critical for accurate coding
- •Ensure the abscess location is specifically documented as brain/cerebral; if documentation indicates other sites (liver, lung), use alternative A06 codes (A06.4 for liver abscess, A06.5 for lung abscess)