A06.4 ICD-10-CM Code: Amebic liver abscess
A06.4 is not a CMS-HCC payment code. MEAT criteria · RAF Calculator · HCC coding software
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FY 2026 Apr update / Certain infectious and parasitic diseases (A00-B99) / Intestinal infectious diseases (A00-A09)
A06.4
Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidanceAmebic liver abscess
A liver abscess (a collection of pus in the liver) caused by a parasitic infection from Entamoeba histolytica, a microscopic organism typically acquired through contaminated food or water. This is a serious complication of amebic infection that requires medical treatment.
CMS-HCC V28
N/A—
Not mapped
CMS-HCC V24
HistoricalHistorical
Not used for CY2026 payment
ACA/HHS
MappedHCC 035_1
Code-level coefficient reference
ESRD/PACE
N/A—
Not mapped
RXHCC
N/A—
Not mapped
Code Book Path
Inclusion Terms
Official- Hepatic amebiasis
Excludes 2
Official- acanthamebiasis (B60.1-)
- Naegleriasis (B60.2)
Related Child Codes
Includes
Official- infection due to Entamoeba histolytica
Excludes 1
Official- other protozoal intestinal diseases (A07.-)
Code First
OfficialICD-10-CM does not list Code First sequencing instructions for A06.4 in this effective period.
Use Additional
OfficialICD-10-CM does not list Use Additional Code instructions for A06.4 in this effective period.
Code Also
OfficialICD-10-CM does not list Code Also instructions for A06.4 in this effective period.
Buddy Documentation Tip
Current with CMS: FY2026 ICD-10-CM Apr 1 update (effective Apr 1 – Sep 30, 2026) · CMS-HCC V28, 100% phased in for payment year 2026. FY2027 code set already staged for October 1, 2026. How HCC Buddy stays current →
Is A06.4 an HCC code?
A06.4 is not in the CMS-HCC V28 or V24 community payment model. A06.4 also appears in the HHS-HCC commercial risk model (HCC 035_1 (HHS-HCC 035_1 adult, RAF varies by metal level)), which is a commercial market model rather than a Medicare Advantage payment mapping.
- Code
- A06.4
- Description
- Amebic liver abscess
- HCC (V28)
- No CMS-HCC V28 mapping
- RAF reference coefficient
- —
- Billable
- Yes
- Payment year
- 2026
Coder workflow notes
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This code does not map to an HCC category in any model (V28, V24, ESRD, RxHCC).
What This Code Means
A06.4 is the ICD-10-CM diagnosis code for amebic liver abscess. A liver abscess (a collection of pus in the liver) caused by a parasitic infection from Entamoeba histolytica, a microscopic organism typically acquired through contaminated food or water. This is a serious complication of amebic infection that requires medical treatment. A06.4 sits in the ICD-10-CM chapter for certain infectious and parasitic diseases (a00-b99), within the section covering intestinal infectious diseases (a00-a09).
A06.4 has no mapping under the CMS-HCC V28 or V24 community payment models. A06.4 also appears in the HHS-HCC commercial risk model (HCC 035_1 (HHS-HCC 035_1 adult, RAF varies by metal level)), which is a commercial market model rather than a Medicare Advantage payment mapping. Do not assign V28 risk adjustment value from this page; verify the applicable model and payment year before using this code for risk adjustment.
Verify documentation confirms amebic etiology (caused by Entamoeba histolytica) rather than other causes of liver abscess, as this distinction is critical for accurate coding.
HCC Buddy maintains structured V28 and V24 mapping, source-labeled coefficient references, and MEAT documentation criteria for A06.4 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.
Coding Tips
- •Verify documentation confirms amebic etiology (caused by Entamoeba histolytica) rather than other causes of liver abscess, as this distinction is critical for accurate coding
- •Ensure the abscess is specifically documented as hepatic/liver involvement; if amebic infection affects other sites (intestine, lung, etc.), those would require separate codes

