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A06.4 ICD-10-CM Code: Amebic liver abscess

A06.4 is not a CMS-HCC payment code. MEAT criteria · RAF Calculator · HCC coding software

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FY 2026 Apr update / Certain infectious and parasitic diseases (A00-B99) / Intestinal infectious diseases (A00-A09)

A06.4

Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidance

Amebic liver abscess

A liver abscess (a collection of pus in the liver) caused by a parasitic infection from Entamoeba histolytica, a microscopic organism typically acquired through contaminated food or water. This is a serious complication of amebic infection that requires medical treatment.

CMS-HCC V28

N/A

Not mapped

CMS-HCC V24

Historical

Historical

Not used for CY2026 payment

ACA/HHS

HCC 035_1

Code-level coefficient reference

ESRD/PACE

N/A

Not mapped

RXHCC

N/A

Not mapped

Code Book Path

Official
A06Amebiasis
A06.4Amebic liver abscess

Inclusion Terms

Official
  • Hepatic amebiasis

Excludes 2

Official
  • acanthamebiasis (B60.1-)
  • Naegleriasis (B60.2)

Related Child Codes

Official
A06.0Acute amebic dysentery
A06.1Chronic intestinal amebiasis
A06.2Amebic nondysenteric colitis
A06.3Ameboma of intestine
A06.5Amebic lung abscess

Includes

Official
  • infection due to Entamoeba histolytica

Excludes 1

Official
  • other protozoal intestinal diseases (A07.-)

Code First

Official

ICD-10-CM does not list Code First sequencing instructions for A06.4 in this effective period.

Use Additional

Official

ICD-10-CM does not list Use Additional Code instructions for A06.4 in this effective period.

Code Also

Official

ICD-10-CM does not list Code Also instructions for A06.4 in this effective period.

Buddy Documentation Tip

HCC Buddy guidance
Verify documentation confirms amebic etiology (caused by Entamoeba histolytica) rather than other causes of liver abscess, as this distinction is critical for accurate coding
Ensure the abscess is specifically documented as hepatic/liver involvement; if amebic infection affects other sites (intestine, lung, etc.), those would require separate codes

Current with CMS: FY2026 ICD-10-CM Apr 1 update (effective Apr 1 – Sep 30, 2026) · CMS-HCC V28, 100% phased in for payment year 2026. FY2027 code set already staged for October 1, 2026. How HCC Buddy stays current →

Is A06.4 an HCC code?

A06.4 is not in the CMS-HCC V28 or V24 community payment model. A06.4 also appears in the HHS-HCC commercial risk model (HCC 035_1 (HHS-HCC 035_1 adult, RAF varies by metal level)), which is a commercial market model rather than a Medicare Advantage payment mapping.

Code
A06.4
Description
Amebic liver abscess
HCC (V28)
No CMS-HCC V28 mapping
RAF reference coefficient
Billable
Yes
Payment year
2026

Coder workflow notes

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This code does not map to an HCC category in any model (V28, V24, ESRD, RxHCC).

What This Code Means

A06.4 is the ICD-10-CM diagnosis code for amebic liver abscess. A liver abscess (a collection of pus in the liver) caused by a parasitic infection from Entamoeba histolytica, a microscopic organism typically acquired through contaminated food or water. This is a serious complication of amebic infection that requires medical treatment. A06.4 sits in the ICD-10-CM chapter for certain infectious and parasitic diseases (a00-b99), within the section covering intestinal infectious diseases (a00-a09).

A06.4 has no mapping under the CMS-HCC V28 or V24 community payment models. A06.4 also appears in the HHS-HCC commercial risk model (HCC 035_1 (HHS-HCC 035_1 adult, RAF varies by metal level)), which is a commercial market model rather than a Medicare Advantage payment mapping. Do not assign V28 risk adjustment value from this page; verify the applicable model and payment year before using this code for risk adjustment.

Verify documentation confirms amebic etiology (caused by Entamoeba histolytica) rather than other causes of liver abscess, as this distinction is critical for accurate coding.

HCC Buddy maintains structured V28 and V24 mapping, source-labeled coefficient references, and MEAT documentation criteria for A06.4 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Coding Tips

  • Verify documentation confirms amebic etiology (caused by Entamoeba histolytica) rather than other causes of liver abscess, as this distinction is critical for accurate coding
  • Ensure the abscess is specifically documented as hepatic/liver involvement; if amebic infection affects other sites (intestine, lung, etc.), those would require separate codes

Child Codes

Code Hierarchy

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