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Z79.633 ICD-10-CM Code: Long term (current) use of mitotic inhibitor

Z79.633 is not a CMS-HCC payment code. MEAT criteria · RAF calculator · free HCC coding tools

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FY 2026 Apr update / Factors influencing health status and contact with health services (Z00-Z99) / Persons with potential health hazards related to family and personal history and certain conditions influencing health status (Z77-Z99)

Z79.633

Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidance

Long term (current) use of mitotic inhibitor

A patient is currently taking a mitotic inhibitor, a chemotherapy drug that prevents cancer cells from dividing by disrupting cell division.

CMS-HCC V28

N/A

Not mapped

CMS-HCC V24

N/A

Not mapped

ACA/HHS

N/A

Not mapped

ESRD/PACE

N/A

Not mapped

RXHCC

N/A

Not mapped

Code Book Path

Official
Z79.6Long term (current) use of immunomodulators and immunosuppressants
Z79.63Long term (current) use of chemotherapeutic agent
Z79.633Long term (current) use of mitotic inhibitor

Inclusion Terms

Official
  • Long term (current) use of paclitaxel
  • Long term (current) use of plant alkaloids
  • Long term (current) use of vinblastine
  • Long term (current) use of vincristine

Excludes 2

Official

ICD-10-CM does not list Excludes 2 notes for Z79.633 in this effective period.

Related Child Codes

Official
Z79.630Long term (current) use of alkylating agent
Z79.631Long term (current) use of antimetabolite agent
Z79.632Long term (current) use of antitumor antibiotic
Z79.634Long term (current) use of topoisomerase inhibitor

Includes

Official

ICD-10-CM does not list Includes notes for Z79.633 in this effective period.

Excludes 1

Official

ICD-10-CM does not list Excludes 1 notes for Z79.633 in this effective period.

Code First

Official

ICD-10-CM does not list Code First sequencing instructions for Z79.633 in this effective period.

Use Additional

Official

ICD-10-CM does not list Use Additional Code instructions for Z79.633 in this effective period.

Code Also

Official

ICD-10-CM does not list Code Also instructions for Z79.633 in this effective period.

Buddy Documentation Tip

HCC Buddy guidance
Use for vinca alkaloids (vincristine, vinblastine) and taxanes (paclitaxel, docetaxel)
Monitor for peripheral neuropathy as a common side effect

Current with CMS: FY2026 ICD-10-CM Apr 1 update (effective Apr 1 – Sep 30, 2026) · CMS-HCC V28, 100% phased in for payment year 2026. FY2027 code set already staged for October 1, 2026. How HCC Buddy stays current →

Is Z79.633 an HCC code?

No. Z79.633 is a billable ICD-10-CM code but does not map to any HCC category in V28, V24, ESRD, or RxHCC.

Code
Z79.633
Description
Long term (current) use of mitotic inhibitor
HCC (V28)
No CMS-HCC V28 mapping
RAF
Billable
Yes
Payment year
2026

Coder workflow notes

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This code does not map to an HCC category in any model (V28, V24, ESRD, RxHCC).

What This Code Means

Z79.633 is the ICD-10-CM diagnosis code for long term (current) use of mitotic inhibitor. A patient is currently taking a mitotic inhibitor, a chemotherapy drug that prevents cancer cells from dividing by disrupting cell division. Z79.633 sits in the ICD-10-CM chapter for factors influencing health status and contact with health services (z00-z99), within the section covering persons with potential health hazards related to family and personal history and certain conditions influencing health status (z77-z99).

Z79.633 is a billable ICD-10-CM code but does not map to a payment HCC under the CMS-HCC V28, V24, ESRD, or RxHCC risk adjustment models. It can be reported on Medicare Advantage encounter data submissions but it does not contribute to a beneficiary's RAF score and therefore does not affect risk-adjusted payments to the plan.

Use for vinca alkaloids (vincristine, vinblastine) and taxanes (paclitaxel, docetaxel).

HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for Z79.633 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Coding Tips

  • Use for vinca alkaloids (vincristine, vinblastine) and taxanes (paclitaxel, docetaxel)
  • Monitor for peripheral neuropathy as a common side effect

Child Codes

Code Hierarchy

Z79.633 code history

Code setChange
FY2023 (effective Oct 1, 2022)Added to the code set

Source: official CMS ICD-10-CM order and addenda files, FY2016 through FY2027.

More on Z79.633

Related condition guides

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