Z17.421
BillableHormone receptor negative with human epidermal growth factor receptor 2 negative status
This code does not map to an HCC category in any model (V28, V24, ESRD, RxHCC).
What This Code Means
A status code indicating that cancer cells are negative for both hormone receptors and HER2, representing triple-negative breast cancer.
Coding Tips
- •Document this code when both hormone receptor and HER2 testing are negative
- •Triple-negative cancers are typically treated with chemotherapy as hormone and HER2 therapies are not effective
Code Hierarchy
└Z17Estrogen, and other hormones and factors receptor status└Z17.4Combined receptor status└Z17.42Hormone receptor negative└Z17.421Hormone receptor negative with human epidermal growth factor receptor 2 negative status
└Z17.421Hormone receptor negative with human epidermal growth factor receptor 2 negative status