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Q04.2

Billable

Holoprosencephaly

HCC Category Mapping

V28HCC 182Spinal Cord Disorders/Injuries
0.282
V24HCC 72Spinal Cord Disorders/Injuries
0.464
ESRDHCC 72Spinal Cord Disorders/Injuries
0.000
RxHCCHCC 155Myelitis and Encephalomyelitis
0.000

What This Code Means

A birth defect where the brain fails to properly divide into two hemispheres, resulting in a single brain structure instead of two separate halves.

Coding Tips

  • Specify the severity level if documented (alobar, semilobar, or lobar)
  • This is often associated with facial abnormalities and other congenital anomalies

Clinical Significance

Holoprosencephaly is a severe brain malformation where the cerebrum fails to divide into hemispheres, causing significant neurological and developmental disabilities. This condition requires intensive multidisciplinary care and has variable prognosis depending on severity.

Documentation Requirements

  • Documentation of failed brain hemisphere division on neuroimaging
  • Specific type of holoprosencephaly if identified (alobar, semilobar, lobar)
  • Associated craniofacial abnormalities documentation
  • Neurological examination findings and developmental assessment
  • Seizure history and neurological complications
  • Endocrine dysfunction assessment (hypothalamic-pituitary)
  • Associated genetic testing results if performed
  • Comprehensive care plan and prognosis documentation

Commonly Confused Codes

Code Hierarchy

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