P55.9
BillableHemolytic disease of newborn, unspecified
HCC Category Mapping
V28HCC 109 — Hemolytic and Aplastic Anemias
0.291What This Code Means
A condition in newborns where red blood cells are destroyed faster than normal, causing anemia and jaundice, but the specific cause is not identified.
Coding Tips
- •Use this code only when the type of hemolytic disease cannot be determined; if a specific cause is known (Rh incompatibility, ABO incompatibility, etc.), use a more specific code
- •This is a perinatal code that should only be used for newborns; verify the patient's age is within the neonatal period
Clinical Significance
Unspecified hemolytic disease represents red blood cell destruction in newborns when the specific cause cannot be determined, still requiring aggressive monitoring and treatment to prevent complications such as severe anemia and kernicterus. Even without specific etiology, this condition demands intensive neonatal care and specialized interventions.
Documentation Requirements
- ✓Evidence of hemolysis in newborn with elevated bilirubin
- ✓Documentation that specific cause cannot be determined
- ✓Laboratory findings showing anemia and signs of hemolysis
- ✓Maternal and newborn blood work including antibody screening
- ✓Exclusion of identifiable causes of hemolysis
- ✓Assessment of hemolysis severity and complications
- ✓Treatment interventions based on clinical severity
- ✓Monitoring plan for bilirubin levels and neurological status
Commonly Confused Codes
P55.1 — ABO isoimmunization (specific vs unspecified cause)P55.8 — Other hemolytic diseases (specified other vs unspecified)P59.9 — Neonatal jaundice, unspecified (jaundice vs hemolytic disease)P61.4 — Other congenital anemias (non-hemolytic vs hemolytic anemia)P58.9 — Neonatal jaundice due to unspecified causes (general jaundice vs hemolysis)
Code Hierarchy
└P55Hemolytic disease of newborn└P55.9Hemolytic disease of newborn, unspecified
└P55.9Hemolytic disease of newborn, unspecified