FY2027 ICD-10-CM reference
P36.4: Sepsis of newborn due to Escherichia coli
By the HCC Buddy Coding Team
The official ICD-10-CM descriptor is Sepsis of newborn due to Escherichia coli. The FY2027 annual edition starts October 1, 2026. Check the edition that applies to the encounter or inpatient discharge, including any April update.
Billable code. Verified against the official FY2027 order file.
FY2027 Tabular instructions
Instructions below include applicable chapter, section and parent-code notes. Each note identifies where it appears in the official source.
Instructional note
Codes from this chapter are for use on newborn records only, never on maternal records
Source: P00-P96 (chapter, inherited).
Includes
conditions that have their origin in the fetal or perinatal period (before birth through the first 28 days after birth) even if morbidity occurs later
Source: P00-P96 (chapter, inherited).
Excludes2
congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
Source: P00-P96 (chapter, inherited).
Excludes2
endocrine, nutritional and metabolic diseases (E00-E88)
Source: P00-P96 (chapter, inherited).
Excludes2
injury, poisoning and certain other consequences of external causes (S00-T88)
Source: P00-P96 (chapter, inherited).
Excludes2
neoplasms (C00-D49)
Source: P00-P96 (chapter, inherited).
Excludes2
tetanus neonatorum (A33)
Source: P00-P96 (chapter, inherited).
Instructional note
Infections acquired in utero, during birth via the umbilicus, or during the first 28 days after birth
Source: P35-P39 (section, inherited).
Excludes2
asymptomatic human immunodeficiency virus [HIV] infection status (Z21)
Source: P35-P39 (section, inherited).
Excludes2
congenital gonococcal infection (A54.-)
Source: P35-P39 (section, inherited).
Excludes2
congenital pneumonia (P23.-)
Source: P35-P39 (section, inherited).
Excludes2
congenital syphilis (A50.-)
Source: P35-P39 (section, inherited).
Excludes2
human immunodeficiency virus [HIV] disease (B20)
Source: P35-P39 (section, inherited).
Excludes2
infant botulism (A48.51)
Source: P35-P39 (section, inherited).
Excludes2
infectious diseases not specific to the perinatal period (A00-B99, J09, J10.-)
Source: P35-P39 (section, inherited).
Excludes2
intestinal infectious disease (A00-A09)
Source: P35-P39 (section, inherited).
Excludes2
laboratory evidence of human immunodeficiency virus [HIV] (R75)
Source: P35-P39 (section, inherited).
Excludes2
tetanus neonatorum (A33)
Source: P35-P39 (section, inherited).
Includes
congenital sepsis
Source: P36 (category, inherited).
Instructional note
code(s), if applicable, to identify severe sepsis (R65.2-) and associated acute organ dysfunction(s)
Source: P36 (category, inherited).
Compare the FY2027 additions, removals and billable-status changes
What does P36.4 mean in FY2027?
The official ICD-10-CM descriptor is Sepsis of newborn due to Escherichia coli. The FY2027 annual edition starts October 1, 2026. Check the edition that applies to the encounter or inpatient discharge, including any April update.
Is P36.4 billable in FY2027?
The FY2027 order file marks P36.4 as billable. Check the complete Tabular instructions and documentation before assigning it.
Does P36.4 map to an HCC?
In the CMS 2027 Initial ICD-10-CM Mappings (payment year 2027, 2026 dates of service), P36.4 maps to CMS-HCC V28 HCC 2 (Septicemia, Sepsis, Systemic Inflammatory Response Syndrome/Shock). For 2027 dates of service, CMS has not yet published the payment year 2028 mappings. ESRD, RxHCC, PACE and HHS-HCC mappings are still pending verification for FY2027.
Source: CMS FY2027 ICD-10-CM order file. Read the FY2027 Official Guidelines.
Review the FY2026 April edition