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M87.10 ICD-10-CM Code: Osteonecrosis due to drugs, unspecified bone

M87.10 is not a CMS-HCC payment code. MEAT criteria · RAF calculator · HCC coding software

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FY 2026 Apr update / Diseases of the musculoskeletal system and connective tissue (M00-M99) / Other osteopathies (M86-M90)

M87.10

Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidance

Osteonecrosis due to drugs, unspecified bone

Death of bone tissue caused by medication use, affecting an unspecified bone location.

Buddy the Bee presenting code insight

Buddy Insight

Drug-induced osteonecrosis of unspecified bone represents medication-related bone death requiring immediate evaluation of causative agents and potential discontinuation or modification of therapy.

CMS-HCC V28

N/A

Not mapped

CMS-HCC V24

HCC 39

RAF 0.401

ACA/HHS

HCC 55

Varies by metal level

ESRD/PACE

HCC 39

RAF 0.092

RXHCC

HCC 80

RAF 0.204

Code Book Path

Official
M87Osteonecrosis
M87.1Osteonecrosis due to drugs
M87.10Osteonecrosis due to drugs, unspecified bone

Inclusion Terms

Official

ICD-10-CM does not list inclusion terms for M87.10 in this effective period.

Excludes 2

Official

ICD-10-CM does not list Excludes 2 notes for M87.10 in this effective period.

Related Child Codes

Official
M87.11Osteonecrosis due to drugs, shoulder
M87.12Osteonecrosis due to drugs, humerus
M87.13Osteonecrosis due to drugs of radius, ulna and carpus
M87.14Osteonecrosis due to drugs, hand and fingers
M87.15Osteonecrosis due to drugs, pelvis and femur

Includes

Official

ICD-10-CM does not list Includes notes for M87.10 in this effective period.

Excludes 1

Official

ICD-10-CM does not list Excludes 1 notes for M87.10 in this effective period.

Code First

Official

ICD-10-CM does not list Code First sequencing instructions for M87.10 in this effective period.

Use Additional

Official
  • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)

Code Also

Official

ICD-10-CM does not list Code Also instructions for M87.10 in this effective period.

Buddy Documentation Tip

HCC Buddy guidance
Clear documentation of drug-induced etiology
Identification of causative medication(s) when possible
Imaging evidence of bone necrosis
Timeline relationship between drug exposure and bone death

MEAT Support

HCC Buddy guidance
Clear documentation of drug-induced etiology
Identification of causative medication(s) when possible
Imaging evidence of bone necrosis
Timeline relationship between drug exposure and bone death

Audit Caution

HCC Buddy guidance
Using when bone location is actually documented (should use specific site code)
Not confirming drug-induced etiology with clear documentation
Missing identification of causative medication
Failing to establish temporal relationship between drug and bone necrosis

Common Mistakes

HCC Buddy guidance
M87.00 — Idiopathic aseptic necrosis unspecified bone (no drug cause identified)
M87.30 — Other secondary osteonecrosis unspecified bone (different secondary cause)
M87.20 — Trauma-related osteonecrosis unspecified bone (injury-related)
Specific site drug-induced codes (M87.11x-M87.18x series when location known)

Current with CMS: FY2026 ICD-10-CM Apr 1 update (effective Apr 1 – Sep 30, 2026) · CMS-HCC V28, 100% phased in for payment year 2026. FY2027 code set already staged for October 1, 2026. How HCC Buddy stays current →

Is M87.10 an HCC code?

Yes. M87.10 maps to Bone/Joint/Muscle Infections/Necrosis under the V24 model but is not retained in V28.

Code
M87.10
Description
Osteonecrosis due to drugs, unspecified bone
HCC (V28)
No CMS-HCC V28 mapping
RAF
Billable
Yes
Payment year
2026

HCC Category Mapping

V24HCC 39, Bone/Joint/Muscle Infections/Necrosis
0.401
ESRDHCC 39, Bone/Joint/Muscle Infections/Necrosis
0.092
RxHCCHCC 80, Bone/Joint/Muscle Infections/Necrosis
0.204

Each model's RAF is its CMS base weight for that model's standard population, so weights are not directly comparable across models: CMS-HCC V28 and V24 use Community, Non-Dual, Aged; ESRD uses the dialysis continuing-enrollee model; RxHCC is the Part D continuing-enrollee, non-low-income, aged weight (a larger scale than CMS-HCC). ACA/HHS has no single weight — it varies by metal level. Actual per-patient RAF contribution depends on member segment, interactions, and the model year used by the payer. V28 is the CMS-HCC model phased in over payment years 2024–2026; V24 remains in use during the transition and for historical data.

Work M87.10 in the Code Book — tabular path, V28 RAF, and MEAT checklist →

MEAT Criteria for M87.10

For M87.10 to count as a valid HCC diagnosis in a given encounter, the provider's documentation must show MEAT: Monitor, Evaluate, Assess, or Treat. A diagnosis from a prior year does not carry forward automatically, it has to be re-documented and supported each calendar year.

  • MMonitor: signs, symptoms, disease progression, or lab trending documented in the note
  • EEvaluate: test results, medication response, or physical findings reviewed by the provider
  • AAssess: explicit mention in the assessment or plan with acknowledgment of status
  • TTreat: medication, referral, procedure, therapy, or counseling tied to the diagnosis

Only one of M/E/A/T is required to support the code, but the documentation must be specific enough to show that the provider actually addressed M87.10 during that encounter, not just copy-forwarded from a problem list.

Coder workflow notes

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What This Code Means

M87.10 is the ICD-10-CM diagnosis code for osteonecrosis due to drugs, unspecified bone. Death of bone tissue caused by medication use, affecting an unspecified bone location. M87.10 sits in the ICD-10-CM chapter for diseases of the musculoskeletal system and connective tissue (m00-m99), within the section covering other osteopathies (m86-m90).

Under the older CMS-HCC V24 model, M87.10 maps to Bone/Joint/Muscle Infections/Necrosis (HCC 39) with a community, non-dual, aged base RAF weight of 0.401. V28 is the CMS-HCC risk adjustment model that reached 100% phase-in for payment year 2026, replacing V24 which was used during the PY2024–PY2025 transition.

Document which medication caused the osteonecrosis (e.g., corticosteroids, bisphosphonates). Because M87.10 maps to a payment HCC, the provider's documentation must satisfy MEAT criteria (Monitor, Evaluate, Assess, or Treat) for the encounter to count toward the patient's Medicare Advantage risk adjustment score. When documentation is ambiguous, coders should issue a provider query rather than assume the highest-specificity variant.

HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for M87.10 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Coding Tips

  • Document which medication caused the osteonecrosis (e.g., corticosteroids, bisphosphonates)
  • Assign a more specific code if the bone location is documented

Clinical Significance

Drug-induced osteonecrosis of unspecified bone represents medication-related bone death requiring immediate evaluation of causative agents and potential discontinuation or modification of therapy. This diagnosis has significant implications for ongoing medication management and requires careful monitoring to prevent progression and additional bone involvement.

Documentation Requirements

  • Clear documentation of drug-induced etiology
  • Identification of causative medication(s) when possible
  • Imaging evidence of bone necrosis
  • Timeline relationship between drug exposure and bone death
  • Clinical findings consistent with osteonecrosis
  • Assessment of need for medication modification
  • Evaluation for other potential affected sites
  • Documentation that specific bone location was not determined

Commonly Confused Codes

  • M87.00: Idiopathic aseptic necrosis unspecified bone (no drug cause identified)
  • M87.30: Other secondary osteonecrosis unspecified bone (different secondary cause)
  • M87.20: Trauma-related osteonecrosis unspecified bone (injury-related)
  • Specific site drug-induced codes (M87.11x-M87.18x series when location known)
  • T36-T50 series: Adverse effects of drugs (for the drug effect itself)

Child Codes

Code Hierarchy

Because M87.10 maps to a payment HCC, the documentation must also satisfy MEAT criteria (Monitor, Evaluate, Assess, or Treat) for the encounter to count toward the patient's risk adjustment score.

Work M87.10 in HCC Buddy

Open M87.10 in the Code Book for the full Index-to-Tabular path, MEAT checklist, and V28 HCC mapping, or in the Encoder to code from a keyword search. Pro includes 7 days to try everything, no card required.