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FY2027 ICD-10-CM reference

J45.41: Moderate persistent asthma with (acute) exacerbation

By the HCC Buddy Coding Team

The official ICD-10-CM descriptor is Moderate persistent asthma with (acute) exacerbation. The FY2027 annual edition starts October 1, 2026. Check the edition that applies to the encounter or inpatient discharge, including any April update.

Billable code. Verified against the official FY2027 order file.

CMS-HCC V28

No V28 HCC for 2026 dates of service (CMS 2027 Initial ICD-10-CM Mappings)

CMS-HCC V24

Not used for payment year 2027 Medicare Advantage payment

ESRD

No category in the PY2026 CMS mapping; CMS 2027 initial file unchanged

PACE

Source verification pending

RxHCC

  • HCC 229: Chronic Obstructive Pulmonary Disease, Bronchiectasis, and Other Asthma

Coefficient pending: payment year 2027 coefficients for this model are not yet verified, so no RAF is shown. Mapping: PY2026 CMS mapping; CMS 2027 initial file unchanged.

HHS-HCC

  • HHS-HCC 161.2

RAF not applicable: HHS-HCC weights vary by metal level. Mapping: HHS-HCC 2026 benefit year.

FY2027 Tabular instructions

Instructions below include applicable chapter, section and parent-code notes. Each note identifies where it appears in the official source.

Instructional note

When a respiratory condition is described as occurring in more than one site and is not specifically indexed, it should be classified to the lower anatomic site (e.g. tracheobronchitis to bronchitis in J40).

Source: J00-J99 (chapter, inherited).

Instructional note

code, where applicable, to identify:

Source: J00-J99 (chapter, inherited).

Instructional note

exposure to environmental tobacco smoke (Z77.22)

Source: J00-J99 (chapter, inherited).

Instructional note

exposure to tobacco smoke in the perinatal period (P96.81)

Source: J00-J99 (chapter, inherited).

Instructional note

history of tobacco dependence (Z87.891)

Source: J00-J99 (chapter, inherited).

Instructional note

occupational exposure to environmental tobacco smoke (Z57.31)

Source: J00-J99 (chapter, inherited).

Instructional note

tobacco dependence (F17.-)

Source: J00-J99 (chapter, inherited).

Instructional note

tobacco use (Z72.0)

Source: J00-J99 (chapter, inherited).

Excludes2

certain conditions originating in the perinatal period (P04-P96)

Source: J00-J99 (chapter, inherited).

Excludes2

certain infectious and parasitic diseases (A00-B99)

Source: J00-J99 (chapter, inherited).

Excludes2

complications of pregnancy, childbirth and the puerperium (O00-O9A)

Source: J00-J99 (chapter, inherited).

Excludes2

congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)

Source: J00-J99 (chapter, inherited).

Excludes2

endocrine, nutritional and metabolic diseases (E00-E88)

Source: J00-J99 (chapter, inherited).

Excludes2

injury, poisoning and certain other consequences of external causes (S00-T88)

Source: J00-J99 (chapter, inherited).

Excludes2

neoplasms (C00-D49)

Source: J00-J99 (chapter, inherited).

Excludes2

smoke inhalation (T59.81-)

Source: J00-J99 (chapter, inherited).

Excludes2

symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

Source: J00-J99 (chapter, inherited).

Excludes1

bronchitis due to chemicals, gases, fumes and vapors (J68.0)

Source: J40-J4B (section, inherited).

Excludes2

cystic fibrosis (E84.-)

Source: J40-J4B (section, inherited).

Includes

allergic (predominantly) asthma

Source: J45 (category, inherited).

Includes

allergic bronchitis NOS

Source: J45 (category, inherited).

Includes

allergic rhinitis with asthma

Source: J45 (category, inherited).

Includes

atopic asthma

Source: J45 (category, inherited).

Includes

extrinsic allergic asthma

Source: J45 (category, inherited).

Includes

hay fever with asthma

Source: J45 (category, inherited).

Includes

idiosyncratic asthma

Source: J45 (category, inherited).

Includes

intrinsic nonallergic asthma

Source: J45 (category, inherited).

Includes

nonallergic asthma

Source: J45 (category, inherited).

Instructional note

code to identify:

Source: J45 (category, inherited).

Instructional note

eosinophilic asthma (J82.83)

Source: J45 (category, inherited).

Instructional note

exposure to environmental tobacco smoke (Z77.22)

Source: J45 (category, inherited).

Instructional note

exposure to tobacco smoke in the perinatal period (P96.81)

Source: J45 (category, inherited).

Instructional note

history of tobacco dependence (Z87.891)

Source: J45 (category, inherited).

Instructional note

occupational exposure to environmental tobacco smoke (Z57.31)

Source: J45 (category, inherited).

Instructional note

tobacco dependence (F17.-)

Source: J45 (category, inherited).

Instructional note

tobacco use (Z72.0)

Source: J45 (category, inherited).

Excludes1

detergent asthma (J69.8)

Source: J45 (category, inherited).

Excludes1

miner's asthma (J60)

Source: J45 (category, inherited).

Excludes1

wheezing NOS (R06.2)

Source: J45 (category, inherited).

Excludes1

wood asthma (J67.8)

Source: J45 (category, inherited).

Excludes2

asthma with chronic obstructive pulmonary disease (J44.89)

Source: J45 (category, inherited).

Excludes2

chronic asthmatic (obstructive) bronchitis (J44.89)

Source: J45 (category, inherited).

Excludes2

chronic obstructive asthma (J44.89)

Source: J45 (category, inherited).

Excludes2

other specified chronic obstructive pulmonary disease (J44.89)

Source: J45 (category, inherited).

Source: CMS FY2027 Tabular List and Alphabetic Index.

Open Tabular instructions and code details

Compare the FY2027 additions, removals and billable-status changes

What does J45.41 mean in FY2027?

The official ICD-10-CM descriptor is Moderate persistent asthma with (acute) exacerbation. The FY2027 annual edition starts October 1, 2026. Check the edition that applies to the encounter or inpatient discharge, including any April update.

Is J45.41 billable in FY2027?

The FY2027 order file marks J45.41 as billable. Check the complete Tabular instructions and documentation before assigning it.

Does J45.41 map to an HCC?

J45.41 has no CMS-HCC V28 category in the CMS 2027 Initial ICD-10-CM Mappings (payment year 2027, 2026 dates of service). Under the PY2026 CMS mapping; CMS 2027 initial file unchanged: no ESRD category; RxHCC HCC 229. Coefficients for these models are pending verification for payment year 2027. HHS-HCC: HCC 161.2 under the HHS-HCC 2026 benefit year mapping (no RAF; HHS-HCC weights vary by metal level). CMS-HCC V24: not used for payment year 2027 Medicare Advantage payment (CMS CY 2027 Rate Announcement). The PACE mapping is still pending verification for FY2027.

Source: CMS FY2027 ICD-10-CM order file. Payment model: CMS CY 2027 Rate Announcement. Read the FY2027 Official Guidelines.

Review the FY2026 April edition