I42.3
BillableEndomyocardial (eosinophilic) disease
HCC Category Mapping
V28HCC 227 — Cardiomyopathy
0.339V24HCC 85 — Congestive Heart Failure
0.368ESRDHCC 85 — Congestive Heart Failure
0.000RxHCCHCC 186 — Heart Failure
0.000What This Code Means
A type of heart muscle disease characterized by abnormal accumulation of eosinophils (a type of white blood cell) in the heart tissue, which weakens the heart's ability to pump blood effectively.
Coding Tips
- •Document the underlying cause if known (e.g., hypereosinophilic syndrome, parasitic infection) as it may affect treatment and prognosis
- •Distinguish from other cardiomyopathies by confirming eosinophilic infiltration through clinical findings or biopsy results
Clinical Significance
Endomyocardial eosinophilic disease is a rare cardiomyopathy characterized by eosinophilic infiltration of the heart muscle and endocardium. It can cause restrictive physiology, heart failure, and thromboembolic events. This condition is often associated with hypereosinophilic syndrome and requires specialized hematologic and cardiac management.
Documentation Requirements
- ✓Provider diagnosis of endomyocardial eosinophilic disease
- ✓Peripheral eosinophilia or tissue eosinophilia documented
- ✓Endomyocardial biopsy results or clinical/imaging evidence supporting the diagnosis
- ✓Underlying etiology if known (hypereosinophilic syndrome, parasitic infection)
- ✓Assessment of cardiac function and thromboembolic risk
Commonly Confused Codes
I42.5 — Other restrictive cardiomyopathy; use when restriction is present but not eosinophilicD72.1 — Eosinophilia; the hematologic condition, not the cardiac diseaseI42.0 — Dilated cardiomyopathy; dilation vs eosinophilic infiltrationI42.8 — Other cardiomyopathies; use for other non-standard cardiomyopathies
Code Hierarchy
└I42Cardiomyopathy└I42.3Endomyocardial (eosinophilic) disease
└I42.3Endomyocardial (eosinophilic) disease