I25.10 ICD-10-CM Code: Atherosclerotic heart disease of native coronary artery without angina pectoris
I25.10 is not a CMS-HCC payment code. MEAT criteria · RAF Calculator · HCC coding software
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FY 2026 Apr update / Diseases of the circulatory system (I00-I99) / Ischemic heart diseases (I20-I25)
I25.10
Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidanceAtherosclerotic heart disease of native coronary artery without angina pectoris
Hardening and narrowing of the heart's blood vessels due to plaque buildup, without chest pain symptoms.
CMS-HCC V28
N/A—
Not mapped
CMS-HCC V24
HistoricalHistorical
Not used for CY2026 payment
ACA/HHS
N/A—
Not mapped
ESRD/PACE
N/A—
Not mapped
RXHCC
N/A—
Not mapped
Code Book Path
Inclusion Terms
Official- Atherosclerotic heart disease NOS
- Atherosclerotic cardiovascular diseaseInherited from I25.1
- Coronary (artery) atheromaInherited from I25.1
- Coronary (artery) atherosclerosisInherited from I25.1
- Coronary (artery) diseaseInherited from I25.1
- Coronary (artery) sclerosisInherited from I25.1
Excludes 2
Official- certain conditions originating in the perinatal period (P04-P96)Inherited from I00-I99, I25, I25.1
- certain infectious and parasitic diseases (A00-B99)Inherited from I00-I99, I25, I25.1
- complications of pregnancy, childbirth and the puerperium (O00-O9A)Inherited from I00-I99, I25, I25.1
- congenital malformations, deformations, and chromosomal abnormalities (Q00-Q99)Inherited from I00-I99, I25, I25.1
- endocrine, nutritional and metabolic diseases (E00-E88)Inherited from I00-I99, I25, I25.1
- injury, poisoning and certain other consequences of external causes (S00-T88)Inherited from I00-I99, I25, I25.1
- neoplasms (C00-D49)Inherited from I00-I99, I25, I25.1
- symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)Inherited from I00-I99, I25, I25.1
- systemic connective tissue disorders (M30-M36)Inherited from I00-I99, I25, I25.1
- transient cerebral ischemic attacks and related syndromes (G45.-)Inherited from I00-I99, I25, I25.1
- non-ischemic myocardial injury (I5A)Inherited from I00-I99, I25, I25.1
- atheroembolism (I75.-)Inherited from I00-I99, I25, I25.1
- atherosclerosis of coronary artery bypass graft(s) and transplanted heart (I25.7-)Inherited from I00-I99, I25, I25.1
Related Codes
Includes
OfficialNo Includes notes are included in this display for I25.10. Check the code and parent instructions in the Code Book.
Excludes 1
OfficialNo Excludes 1 notes are included in this display for I25.10. Check the code and parent instructions in the Code Book.
Code First
OfficialNo Code First sequencing instructions are included in this display for I25.10. Check the code and parent instructions in the Code Book.
Use Additional
Official- code to identify:Inherited from I25, I25.1
- chronic total occlusion of coronary artery (I25.82)Inherited from I25, I25.1
- exposure to environmental tobacco smoke (Z77.22)Inherited from I25, I25.1
- history of tobacco dependence (Z87.891)Inherited from I25, I25.1
- occupational exposure to environmental tobacco smoke (Z57.31)Inherited from I25, I25.1
- tobacco dependence (F17.-)Inherited from I25, I25.1
- tobacco use (Z72.0)Inherited from I25, I25.1
- code, if applicable, to identify:Inherited from I25, I25.1
- coronary atherosclerosis due to calcified coronary lesion (I25.84)Inherited from I25, I25.1
- coronary atherosclerosis due to lipid rich plaque (I25.83)Inherited from I25, I25.1
Code Also
Official- the presence of hypertension (I10-I1A)Inherited from I20-I25
Buddy Documentation Tip
MEAT Support
Audit Caution
Common Mistakes
Current with CMS: FY2026 ICD-10-CM Apr 1 update (effective Apr 1 – Sep 30, 2026) · CMS-HCC V28, 100% phased in for payment year 2026. FY2027 code set already staged for October 1, 2026. How HCC Buddy stays current →
Is I25.10 an HCC code?
I25.10 is not in the CMS-HCC V28 or V24 community payment model. I25.10 has a separate mapping under the Part D RxHCC model (HCC 188 (Coronary Artery Disease)); the applicable result needs member context.
- Code
- I25.10
- Description
- Atherosclerotic heart disease of native coronary artery without angina pectoris
- HCC (V28)
- No CMS-HCC V28 mapping
- RAF reference coefficient
- —
- Billable
- Yes
- Payment year
- 2026
Coder workflow notes
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This code does not map to an HCC category in any model (V28, V24, ESRD, RxHCC).
What This Code Means
I25.10 is the ICD-10-CM diagnosis code for atherosclerotic heart disease of native coronary artery without angina pectoris. Hardening and narrowing of the heart's blood vessels due to plaque buildup, without chest pain symptoms. I25.10 sits in the ICD-10-CM chapter for diseases of the circulatory system (i00-i99), within the section covering ischemic heart diseases (i20-i25).
I25.10 has no mapping under the CMS-HCC V28 or V24 community payment models. I25.10 has a separate mapping under the Part D RxHCC model (HCC 188 (Coronary Artery Disease)); the applicable result needs member context. Do not assign V28 risk adjustment value from this page; verify the applicable model and payment year before using this code for risk adjustment.
Documentation must establish atherosclerotic heart disease of a native coronary artery without angina. Review prior testing and the provider's current assessment in the full eligible record. Carrying a diagnosis forward annually does not by itself establish support under the applicable coding, encounter, program and payer requirements.
HCC Buddy maintains structured V28 and V24 mapping, source-labeled coefficient references, and MEAT documentation criteria for I25.10 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.
Coding Tips
- •Documentation must establish atherosclerotic heart disease of a native coronary artery without angina. Review prior testing and the provider's current assessment in the full eligible record. Carrying a diagnosis forward annually does not by itself establish support under the applicable coding, encounter, program and payer requirements.
- •Do not default to I25.10 when angina is documented, I25.11x captures CAD with angina and is preferred whenever the chart supports chest pain attributed to coronary disease. Prior CABG or stent placement alone does not establish graft atherosclerosis or exclude I25.10 when native coronary disease without angina is documented. Select the documented native-vessel or graft disease code, then apply the Tabular instructions and applicable status codes, such as Z95.1 for bypass graft presence or Z95.5 for coronary angioplasty implant and graft presence.
- •This is the baseline native-vessel CAD code and one of the most frequently carried-forward diagnoses in MA panels, but it no longer carries a risk-adjustment coefficient.
Documentation Requirements
- ✓Provider documentation of coronary artery disease or atherosclerotic heart disease
- ✓Specification that native (non-grafted) coronary arteries are involved
- ✓Confirmation that the patient does not currently have angina pectoris
- ✓Supporting diagnostic evidence (cardiac catheterization, coronary computed tomography angiography, or stress test)
- ✓Current management plan (medications, lifestyle modifications)
Commonly Confused Codes
- •I25.110: Atherosclerotic heart disease of native coronary artery with unstable angina: presence of angina changes the code and adds HCC value
- •I25.119: Atherosclerotic heart disease of native coronary artery with unspecified angina: if any angina is documented
- •I25.810: Atherosclerosis of coronary artery bypass graft without angina: for grafted vessels
- •I25.5: Ischemic cardiomyopathy: when coronary artery disease has caused myocardial dysfunction
- •I25.9: Chronic ischemic heart disease, unspecified: less specific than I25.10

