Skip to content

I21.01

Billable

ST elevation (STEMI) myocardial infarction involving left main coronary artery

HCC Category Mapping

V28HCC 228Acute Myocardial Infarction
0.000
V24HCC 86Acute Myocardial Infarction
0.274
ESRDHCC 86Acute Myocardial Infarction
0.000
RxHCCHCC 188Coronary Artery Disease and Angina
0.000

What This Code Means

A heart attack caused by a blood clot blocking the left main coronary artery, with characteristic ST segment elevation visible on an EKG.

Coding Tips

  • This code requires documentation of STEMI and specific identification of left main coronary artery involvement
  • Verify the timing of the MI (initial episode vs. subsequent episode) as this affects the 7th character assignment

Clinical Significance

STEMI involving the left main coronary artery represents one of the most life-threatening acute cardiac events, as the left main supplies approximately 75% of the left ventricular myocardium. This code carries significant risk adjustment weight due to the extreme acuity and resource utilization associated with left main occlusion. Accurate capture is critical for reflecting the true severity of illness in the patient population.

Documentation Requirements

  • Explicit documentation of ST elevation myocardial infarction (STEMI)
  • Identification of the left main coronary artery as the culprit vessel
  • Electrocardiogram findings showing ST elevation pattern consistent with left main involvement
  • Cardiac catheterization or angiography results confirming left main occlusion
  • Troponin or other cardiac biomarker elevation
  • Timing of the event — initial episode of care within first 4 weeks
  • Treatment interventions (percutaneous coronary intervention, coronary artery bypass graft, or thrombolytics)

Commonly Confused Codes

Code Hierarchy

Open I21.01 in the Interactive Encoder

See full code details, AI coding tips, HCC mappings, and related codes in our interactive encoder. Start your 14-day Pro trial — no credit card required.